BIOTHERM Life Plankton Regenerating Serum Versus Clarins Double Serum Complete Age-Defying Concentrate
This barrier-repair serum is formulated around Bifida Ferment Lysate and Squalane to strengthen the skin barrier and hydrate skin.
This anti-aging serum is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBifida Ferment Lysate
Skin ConditioningGlycerin
HumectantPentylene Glycol
Skin ConditioningSqualane
EmollientSaccharide Isomerate
HumectantSodium Hyaluronate
HumectantSodium Hydroxide
BufferingAdenosine
Skin ConditioningAscorbyl Glucoside
AntioxidantAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingHydrolyzed Hyaluronic Acid
HumectantHydroxyacetophenone
AntioxidantCaprylyl Glycol
EmollientVitreoscilla Ferment
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Lactic Acid
BufferingAcetic Acid
BufferingXanthan Gum
EmulsifyingFaex Extract
Skin ConditioningDecyl Glucoside
CleansingOctyldodecanol
EmollientSodium Benzoate
MaskingParfum
MaskingWater, Bifida Ferment Lysate, Glycerin, Pentylene Glycol, Squalane, Saccharide Isomerate, Sodium Hyaluronate, Sodium Hydroxide, Adenosine, Ascorbyl Glucoside, Ammonium Polyacryloyldimethyl Taurate, Hydrolyzed Hyaluronic Acid, Hydroxyacetophenone, Caprylyl Glycol, Vitreoscilla Ferment, Trisodium Ethylenediamine Disuccinate, Lactic Acid, Acetic Acid, Xanthan Gum, Faex Extract, Decyl Glucoside, Octyldodecanol, Sodium Benzoate, Parfum
Water
Skin ConditioningSqualane
EmollientHexyl Laurate
EmollientGlycerin
HumectantPentylene Glycol
Skin ConditioningPropanediol
SolventSilybum Marianum Seed Oil
Skin ConditioningButylene Glycol
HumectantEthylene/Propylene/Styrene Copolymer
Parfum
MaskingFructose
HumectantTromethamine
BufferingCarbomer
Emulsion StabilisingHydroxyacetophenone
AntioxidantAvena Sativa Kernel Extract
AbrasiveEscin
TonicTocopheryl Acetate
AntioxidantEthylhexylglycerin
Skin ConditioningAloe Barbadensis Leaf Juice Powder
Skin ConditioningSodium Acetylated Hyaluronate
HumectantTheobroma Cacao Extract
Skin ConditioningCaprylic/Capric Triglyceride
MaskingAesculus Hippocastanum Extract
AntioxidantLeontopodium Alpinum Flower/Leaf Extract
Skin ConditioningDisodium EDTA
Maltodextrin
AbsorbentXanthan Gum
EmulsifyingButylene/Ethylene/Styrene Copolymer
Curcuma Longa Root Extract
AntioxidantPersea Gratissima Oil Unsaponifiables
Skin ConditioningMelissa Officinalis Leaf Extract
Skin ConditioningCaramel
Cosmetic ColorantHippophae Rhamnoides Kernel Extract
MaskingSodium Lactate
BufferingMusa Sapientum Fruit Extract
Skin ConditioningOenothera Biennis Flower/Leaf/Stem Extract
Skin ConditioningHarungana Madagascariensis Extract
Skin ConditioningKalanchoe Pinnata Leaf Extract
MaskingMangifera Indica Leaf Extract
Skin ConditioningSodium Benzoate
MaskingCitric Acid
BufferingCentaurea Cyanus Flower Extract
AstringentTocopherol
AntioxidantHedychium Coronarium Root Extract
MaskingCoco-Glucoside
CleansingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantDipsacus Sylvestris Extract
Skin ConditioningGlycine Soja Oil
EmollientArundo Donax Stem Extract
Skin ConditioningJania Rubens Extract
Skin ConditioningPotassium Sorbate
PreservativeSodium Citrate
BufferingMalpighia Emarginata Seed Extract
Skin ConditioningArbutus Unedo Fruit Extract
AntioxidantPalmitoyl Tripeptide-1
Skin ConditioningCI 14700
Cosmetic ColorantPalmitoyl Tetrapeptide-7
Skin ConditioningWater, Squalane, Hexyl Laurate, Glycerin, Pentylene Glycol, Propanediol, Silybum Marianum Seed Oil, Butylene Glycol, Ethylene/Propylene/Styrene Copolymer, Parfum, Fructose, Tromethamine, Carbomer, Hydroxyacetophenone, Avena Sativa Kernel Extract, Escin, Tocopheryl Acetate, Ethylhexylglycerin, Aloe Barbadensis Leaf Juice Powder, Sodium Acetylated Hyaluronate, Theobroma Cacao Extract, Caprylic/Capric Triglyceride, Aesculus Hippocastanum Extract, Leontopodium Alpinum Flower/Leaf Extract, Disodium EDTA, Maltodextrin, Xanthan Gum, Butylene/Ethylene/Styrene Copolymer, Curcuma Longa Root Extract, Persea Gratissima Oil Unsaponifiables, Melissa Officinalis Leaf Extract, Caramel, Hippophae Rhamnoides Kernel Extract, Sodium Lactate, Musa Sapientum Fruit Extract, Oenothera Biennis Flower/Leaf/Stem Extract, Harungana Madagascariensis Extract, Kalanchoe Pinnata Leaf Extract, Mangifera Indica Leaf Extract, Sodium Benzoate, Citric Acid, Centaurea Cyanus Flower Extract, Tocopherol, Hedychium Coronarium Root Extract, Coco-Glucoside, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Dipsacus Sylvestris Extract, Glycine Soja Oil, Arundo Donax Stem Extract, Jania Rubens Extract, Potassium Sorbate, Sodium Citrate, Malpighia Emarginata Seed Extract, Arbutus Unedo Fruit Extract, Palmitoyl Tripeptide-1, CI 14700, Palmitoyl Tetrapeptide-7
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenoneParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum