ZO Skin Health Recovery Crème Versus La Roche-Posay Substiane
Updated on June 12, 2025
Overview
What they are
These products are both reef safe general moisturizers. They have a total of 9 ingredients in common
Cool Features
They both contain peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, parabens or sulfates
What's Inside
They both contain oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ZO Skin Health Recovery Crème 51 ingredients
La Roche-Posay Substiane 33 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
ZO Skin Health Recovery Crème 51 ingredients
La Roche-Posay Substiane 33 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
Emollient
Ethylhexyl Isononanoate
EmollientLactococcus Ferment Lysate
Skin ConditioningGlycerin
Humectant
Stearic Acid
Cleansing
Arachidyl Alcohol
EmollientCaprylic/Capric/Myristic/Stearic Triglyceride
EmollientSqualane
Emollient
Hydrogenated Coco-Glycerides
Emollient
Hydrolyzed Vegetable Protein
Skin ConditioningPolyacrylate-13
Glyceryl Stearate
Emollient
Helianthus Annuus Seed Oil Unsaponifiables
Emollient
PEG-100 Stearate
Behenyl Alcohol
Emollient
Linoleic Acid
Cleansing
Arachidyl Glucoside
EmulsifyingPolysorbate 20
Emulsifying
Butyrospermum Parkii Butter
Skin Conditioning
Melilotus Officinalis Extract
AstringentEpilobium Angustifolium Flower/Leaf/Stem Extract
Skin ConditioningEvodia Rutaecarpa Fruit Extract
Skin ConditioningGlycine Soja Sterols
Emollient
Retinyl Palmitate
Skin Conditioning
Retinol
Skin Conditioning
Tocopherol
Antioxidant
Caprylic/Capric Triglyceride
Masking
Polyisobutene
Butylene Glycol
Humectant
Caprylyl Glycol
EmollientCarbomer
Emulsion StabilisingCeramide Ng
Skin Conditioning
Polyglutamic Acid
Skin Conditioning
Hexylene Glycol
EmulsifyingCaprooyl Tetrapeptide-3
Skin Protecting
Phospholipids
Skin Conditioning
Lecithin
Emollient
Biosaccharide Gum-4
Skin Conditioning
Micrococcus Lysate
Skin ConditioningBHT
Antioxidant
Acetyl Hexapeptide-8
Humectant
Dextran
Trehalose
Humectant
Tetrasodium EDTA
Sodium Hydroxide
BufferingCitric Acid
Buffering
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningSodium Benzoate
Masking
Sorbic Acid
Preservative
Water, Dimethicone, Ethylhexyl Isononanoate, Lactococcus Ferment Lysate, Glycerin, Stearic Acid, Arachidyl Alcohol, Caprylic/Capric/Myristic/Stearic Triglyceride, Squalane, Hydrogenated Coco-Glycerides, Hydrolyzed Vegetable Protein, Polyacrylate-13, Glyceryl Stearate, Helianthus Annuus Seed Oil Unsaponifiables, PEG-100 Stearate, Behenyl Alcohol, Linoleic Acid, Arachidyl Glucoside, Polysorbate 20, Butyrospermum Parkii Butter, Melilotus Officinalis Extract, Epilobium Angustifolium Flower/Leaf/Stem Extract, Evodia Rutaecarpa Fruit Extract, Glycine Soja Sterols, Retinyl Palmitate, Retinol, Tocopherol, Caprylic/Capric Triglyceride, Polyisobutene, Butylene Glycol, Caprylyl Glycol, Carbomer, Ceramide Ng, Polyglutamic Acid, Hexylene Glycol, Caprooyl Tetrapeptide-3, Phospholipids, Lecithin, Biosaccharide Gum-4, Micrococcus Lysate, BHT, Acetyl Hexapeptide-8, Dextran, Trehalose, Tetrasodium EDTA, Sodium Hydroxide, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Sorbic Acid
Water
Skin ConditioningGlycerin
Humectant
Butyrospermum Parkii Butter
Skin Conditioning
Cyclohexasiloxane
Emollient
Prunus Armeniaca Kernel Oil
Masking
Pentaerythrityl Tetraethylhexanoate
Emollient
Isohexadecane
EmollientZea Mays Starch
AbsorbentSilica
Abrasive
Hydroxypropyl Tetrahydropyrantriol
Skin ConditioningCera Alba
Emollient
Stearic Acid
Cleansing
Dimethicone
Emollient
Palmitic Acid
Emollient
PEG-100 Stearate
Glyceryl Stearate
Emollient
Propylene Glycol
Humectant
PEG-20 Stearate
Emulsifying
Bis-PEG-18 Methyl Ether Dimethyl Silane
EmollientStearyl Alcohol
Emollient
Dimethiconol
Emollient
Arginine PCA
HumectantSerine
Masking
Disodium EDTA
Hydrolyzed Linseed Extract
Skin ConditioningAcetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Polysorbate 80
Emulsifying
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Antioxidant
Sodium Benzoate
Masking
Phenoxyethanol
Preservative
Benzoic Acid
Masking
Parfum
Masking
Water, Glycerin, Butyrospermum Parkii Butter, Cyclohexasiloxane, Prunus Armeniaca Kernel Oil, Pentaerythrityl Tetraethylhexanoate, Isohexadecane, Zea Mays Starch, Silica, Hydroxypropyl Tetrahydropyrantriol, Cera Alba, Stearic Acid, Dimethicone, Palmitic Acid, PEG-100 Stearate, Glyceryl Stearate, Propylene Glycol, PEG-20 Stearate, Bis-PEG-18 Methyl Ether Dimethyl Silane, Stearyl Alcohol, Dimethiconol, Arginine PCA, Serine, Disodium EDTA, Hydrolyzed Linseed Extract, Acetyl Dipeptide-1 Cetyl Ester, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Benzoate, Phenoxyethanol, Benzoic Acid, Parfum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.
Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Butyrospermum Parkii ButterDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePeg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateStearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.
As an emollient, stearic acid helps soften skin. It aids the skin's protective barrier by preventing water loss. It also provides a gentle cleansing effect without stripping away natural oils.
Stearic acid may also be used to enhance the texture of products. It can add volume and stabilize ingredients such as water and oil. This can help water and oil ingredients from separating.
Sources of stearic acid include animal or vegetable fats/oils such as coconut or shea. It can be naturally found in butter, cocoa butter, shea butter, vegetable fats, and animal tallow.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about Stearic AcidWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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