Quality First Derma Laser Azelaic Acid 100 Ulthera AZ Serum Versus Anua Azelaic Acid 15+ Intense Calming Serum
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Galactomyces Ferment Filtrate
HumectantButylene Glycol
HumectantNiacinamide
SmoothingDiglycerin
HumectantAzelaic Acid
BufferingDipotassium Glycyrrhizate
HumectantMelaleuca Alternifolia Leaf Oil
AntioxidantCeramide NP
Skin ConditioningCentella Asiatica Extract
CleansingScutellaria Baicalensis Root Extract
AstringentPolygonum Cuspidatum Root Extract
AntioxidantGlycyrrhiza Glabra Root Extract
BleachingCamellia Sinensis Leaf Extract
AntimicrobialRosmarinus Officinalis Leaf Extract
AntimicrobialAnthemis Nobilis Flower Extract
MaskingTripropylene Glycol
AntioxidantHydrogenated Lecithin
EmulsifyingPhytosterols
Skin ConditioningPEG-60 Hydrogenated Castor Oil
EmulsifyingEthylhexylglycerin
Skin Conditioning1,2-Hexanediol
Skin ConditioningCalcium Carbonate
AbrasiveSilver Oxide
AntimicrobialCitric Acid
BufferingSodium Citrate
BufferingWater
Skin ConditioningLavandula Angustifolia Oil
MaskingCitrus Limon Peel Oil
MaskingCitrus Aurantifolia Oil
CleansingLemongrass Oil
Juniperus Officinalis Oil
Rosmarinus Officinalis Leaf Oil
MaskingGalactomyces Ferment Filtrate, Butylene Glycol, Niacinamide, Diglycerin, Azelaic Acid, Dipotassium Glycyrrhizate, Melaleuca Alternifolia Leaf Oil, Ceramide NP, Centella Asiatica Extract, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis Leaf Extract, Anthemis Nobilis Flower Extract, Tripropylene Glycol, Hydrogenated Lecithin, Phytosterols, PEG-60 Hydrogenated Castor Oil, Ethylhexylglycerin, 1,2-Hexanediol, Calcium Carbonate, Silver Oxide, Citric Acid, Sodium Citrate, Water, Lavandula Angustifolia Oil, Citrus Limon Peel Oil, Citrus Aurantifolia Oil, Lemongrass Oil, Juniperus Officinalis Oil, Rosmarinus Officinalis Leaf Oil
Water
Skin ConditioningPropylene Glycol
HumectantAzelaic Acid
BufferingSodium Hydroxide
Buffering1,2-Hexanediol
Skin ConditioningCentella Asiatica Extract
CleansingDipropylene Glycol
HumectantButylene Glycol
HumectantPanthenol
Skin ConditioningHydroxyethylcellulose
Emulsion StabilisingGlycerin
HumectantEthylhexylglycerin
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningSalicylic Acid
MaskingBiosaccharide Gum-1
HumectantAllantoin
Skin ConditioningDipotassium Glycyrrhizate
HumectantMelia Azadirachta Flower Extract
Skin ConditioningSodium Hyaluronate
HumectantMelaleuca Alternifolia Leaf Oil
AntioxidantSuccinic Acid
BufferingTotarol
AntioxidantBeta-Glucan
Skin ConditioningDextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningCentella Asiatica Leaf Extract
Skin ConditioningCentella Asiatica Root Extract
Skin ConditioningMadecassoside
AntioxidantAsiaticoside
AntioxidantAsiatic Acid
Skin ConditioningMadecassic Acid
Skin ConditioningTocopherol
AntioxidantSqualane
EmollientZinc PCA
HumectantChlorella Vulgaris Extract
Skin ConditioningCeramide NP
Skin ConditioningSodium Hyaluronate Dimethylsilanol
HumectantHydrolyzed Hyaluronic Acid
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantPotassium Hyaluronate
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
HumectantSodium Acetylated Hyaluronate
HumectantWater, Propylene Glycol, Azelaic Acid, Sodium Hydroxide, 1,2-Hexanediol, Centella Asiatica Extract, Dipropylene Glycol, Butylene Glycol, Panthenol, Hydroxyethylcellulose, Glycerin, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Salicylic Acid, Biosaccharide Gum-1, Allantoin, Dipotassium Glycyrrhizate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Melaleuca Alternifolia Leaf Oil, Succinic Acid, Totarol, Beta-Glucan, Dextrin, Theobroma Cacao Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Tocopherol, Squalane, Zinc PCA, Chlorella Vulgaris Extract, Ceramide NP, Sodium Hyaluronate Dimethylsilanol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinThis ingredient is also known as tea tree oil. It has antioxidant, anti-inflammatory, and antimicrobial properties.
Tea tree oil is a complex lipophilic (fat-loving) oil that contains around 100 compounds with terpinen-4-ol being the most abundant (~40%).
Terpinen-4-ol is responsible for tea tree oil's broad-spectrum antimicrobial activity and makes it a well-researched option for acne.
Clinical studies support 5% tea tree oil as an effective topical treatment for mild to moderate acne. A study with 124 patients compared 5% tea tree oil gel to 5% benzoyl peroxide and both reduced acne (though tea tree oil worked more slowly).
Besides acne, it is also seen in anti-dandruff shampoos and scalp treatments for it's antimicrobial and anti-seborrheic properties.
Safety-wise, the allergic potential of low concentrations on healthy skin is considered low. However, oxidized (old or improperly stored) tea tree oil is a stronger sensitizer.
Irritation can also occur if using the undiluted oil on skin; it's best to use this ingredient as part of a carefully crafted cosmetic formula. This is because regulations require tea tree oil in cosmetics to be stabilized to prevent degradation.
This ingredient has been deemed safe up to 2% in shampoo, 1% in cleansers, and 0.1% in face cream by the EU's Scientific Committee on Consumer Safety (SCCS).
There is some lab evidence that tea tree oil is antifungal against Malassezia, but it is a supportive option at best and not a replacement for proven antifungal treatments.
Learn more about Melaleuca Alternifolia Leaf OilWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water