Versus

Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream Versus La Roche-Posay Toleriane Double Repair Face Moisturizer

General Moisturizer
General Moisturizer
American Brand United States
French Brand France

Updated on June 26, 2024

Overview

What they are

These products are both reef safe general moisturizers. They have a total of 7 ingredients in common

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Peptide Skinjection Moisture Infusion Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Olive Oil Decyl Esters

Oil IconNot safe for Fungal Acne Icon

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Polysilicone-11

Batyl Alcohol

Emollient

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Tripeptide-10 Citrulline

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Acetyl Tetrapeptide-11

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-9

Skin Conditioning
Peptide Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-2

Skin Conditioning
Peptide Icon

Acetyl Octapeptide-3

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Hexapeptide-19

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Oligopeptide

Cleansing
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Natto Gum

Sodium Polyglutamate

Humectant

Squalene

Emollient
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Mica

Cosmetic Colorant
May worsen Eczema Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Sorbic Acid

Preservative
Preservative Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Cereus Grandiflorus Flower Extract

Skin Conditioning

Pseudoalteromonas Ferment Extract

Humectant
Not safe for Fungal Acne Icon

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Magnesium Chloride

Phenoxyethanol

Preservative
Preservative Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Silanetriol Trehalose Ether

Emollient

Mannitol

Humectant
Helps hydrate Dry Skin Icon

Phytosterols

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Polyglyceryl-10 Myristate

Skin Conditioning
Not safe for Fungal Acne Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Dimethyl Isosorbide

Solvent

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Caprylyl Glycol

Emollient

Sodium Hydroxide

Buffering

Laureth-12

Emulsifying

Hydrolyzed Wheat Protein

Skin Conditioning

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Disodium Phosphate

Buffering

Hydrolyzed Soy Protein

Humectant
Helps hydrate Dry Skin Icon

Carbomer

Emulsion Stabilising
1 / 0

Dextran

Helps hydrate Dry Skin Icon

Ethylhexylglycerin

Skin Conditioning

Sodium Lactate

Buffering

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Sodium Phosphate

Buffering

Xanthan Gum

Emulsifying

Triethanolamine

Buffering
2 / 0

Acrylates Copolymer

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

10 Routines
40% use in am
60% use in pm
90% use every day
2,067 Routines
50% use in am
50% use in pm
97% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream 71 ingredients

Peptide Skinjection Moisture Infusion Cream hasn't been rated yet.
Rate it now

La Roche-Posay Toleriane Double Repair Face Moisturizer 18 ingredients

3.3 /5
from 24 ratings
No Scent (6) Light (5) Works Well (4)
Jnke.'s avatar

Jnke.

4 years ago
Review

Good, but not for me.
Purchased after I damaged my barrier and needed something simple- Texture is nice & light, not at all greasy or heavy. No scent. Does not leave me shiney or oily. But not heavy enough for my current dry skin & needs to be reapplied after a few hours.... I do for the most part really like this moisturizer, but will not be repurchasing after seeing the product info.

rhondarichardson's avatar

Rhonda

7 months ago
Review

Pilled a lot and clogged my pores making them way worse

#pilling