Versus

Paula's Choice Defense Nightly Reconditioning Moisturizer Versus Clinique Dramatically Different Moisturizing Gel

Night Moisturizer
General Moisturizer
American Brand United States
American Brand United States

Updated on July 18, 2023

Overview

What they are

These products are both reef safe . They have a total of 5 ingredients in common

Cool Features

They both contain exfoliants, hyaluronic acid and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Defense Nightly Reconditioning Moisturizer

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Ethylhexyl Palmitate

Emollient
2-3 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Isoamyl Laurate

Emollient
Not safe for Fungal Acne Icon

Prunus Serotina Fruit Extract

Masking

Almond/Borage/Linseed/Olive Acids/Glycerides

Antioxidant
Antioxidant IconNot safe for Fungal Acne Icon

Medicago Sativa Extract

Tonic

Sesamum Indicum Seed

Abrasive
Exfoliant Icon

Hydrolyzed Eruca Sativa Leaf

Antioxidant
Antioxidant Icon

Sclerocarya Birrea Seed Oil

Humectant
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Hydrolyzed Algae Extract

Skin Conditioning

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Dipeptide-10

Skin Conditioning
Peptide Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Ceramide Ng

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Cocoyl Proline

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Eclipta Prostrata Extract

Skin Conditioning

Potassium Azeloyl Diglycinate

Skin Conditioning
Good for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Opuntia Ficus-Indica Stem Extract

Skin Conditioning
Helps reduce irritation Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Moringa Oleifera Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconNot safe for Fungal Acne Icon

Alaria Esculenta Extract

Skin Protecting

Adenosine Phosphate

Skin Conditioning

PEG-10 Phytosterol

Emulsifying

Tribehenin

Emollient
0 / 0 Not safe for Fungal Acne Icon

Hydrolyzed Vegetable Protein

Skin Conditioning

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Sodium Gluconate

Skin Conditioning

Zinc Gluconate

Skin Conditioning
Helps fight Acne Icon

Copper Gluconate

Skin Conditioning
Good for Scar Healing Icon

Magnesium Aspartate

Skin Conditioning

Cetearyl Olivate

Not safe for Fungal Acne Icon

Isoamyl Cocoate

Can worsen Dry Skin IconNot safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Polyglyceryl-10 Caprylate/Caprate

Emulsifying

Microcrystalline Cellulose

Absorbent

C12-15 Alkyl Benzoate

Antimicrobial

Xanthan Gum

Emulsifying

Pentylene Glycol

Skin Conditioning

Butylene Glycol Stearate

Emollient

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Ethylhexylglycerin

Skin Conditioning
Dramatically Different Moisturizing Gel

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Learn more about Trehalose
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

4 Routines
0% use in am
100% use in pm
100% use every day
556 Routines
54% use in am
46% use in pm
97% use every day
When to use See routines that use it ->

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Light 63% Hydrating 50% No Scent 25%