Paula's Choice Defense Nightly Reconditioning Moisturizer
A cruelty-free night moisturizer that contains ceramides, exfoliants, hyaluronic acid, peptides and vitamin e.
Overview
What it is
Night moisturizer with 49 ingredients that contains ceramides, exfoliants, hyaluronic acid, peptides and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
Fun facts
Paula's Choice is from United States. This product is used in 3 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningGlycerin
HumectantEthylhexyl Palmitate
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingIsoamyl Laurate
EmollientPrunus Serotina Fruit Extract
MaskingAlmond/Borage/Linseed/Olive Acids/Glycerides
AntioxidantMedicago Sativa Extract
TonicSesamum Indicum Seed
AbrasiveHydrolyzed Eruca Sativa Leaf
AntioxidantSclerocarya Birrea Seed Oil
HumectantHydrolyzed Algae Extract
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningPalmitoyl Dipeptide-10
Skin ConditioningSodium Hyaluronate
HumectantCeramide Ng
Skin ConditioningHelianthus Annuus Seed Oil
EmollientCocoyl Proline
Skin ConditioningTocopherol
AntioxidantAllantoin
Skin ConditioningTrehalose
HumectantEclipta Prostrata Extract
Skin ConditioningPotassium Azeloyl Diglycinate
Skin ConditioningOpuntia Ficus-Indica Stem Extract
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialMoringa Oleifera Seed Oil
EmollientAlaria Esculenta Extract
Skin ProtectingAdenosine Phosphate
Skin ConditioningPEG-10 Phytosterol
EmulsifyingTribehenin
EmollientHydrolyzed Vegetable Protein
Skin ConditioningSorbitan Olivate
EmulsifyingSodium Gluconate
Skin ConditioningZinc Gluconate
Skin ConditioningCopper Gluconate
Skin ConditioningMagnesium Aspartate
Skin ConditioningCetearyl Olivate
Isoamyl Cocoate
Caprylic/Capric Triglyceride
MaskingPolyglyceryl-10 Caprylate/Caprate
EmulsifyingMicrocrystalline Cellulose
AbsorbentC12-15 Alkyl Benzoate
AntimicrobialXanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningButylene Glycol Stearate
EmollientPhenoxyethanol
PreservativePotassium Sorbate
PreservativeEthylhexylglycerin
Skin ConditioningWater, Glycerin, Ethylhexyl Palmitate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isoamyl Laurate, Prunus Serotina Fruit Extract, Almond/Borage/Linseed/Olive Acids/Glycerides, Medicago Sativa Extract, Sesamum Indicum Seed, Hydrolyzed Eruca Sativa Leaf, Sclerocarya Birrea Seed Oil, Hydrolyzed Algae Extract, Palmitoyl Hexapeptide-12, Palmitoyl Dipeptide-10, Sodium Hyaluronate, Ceramide Ng, Helianthus Annuus Seed Oil, Cocoyl Proline, Tocopherol, Allantoin, Trehalose, Eclipta Prostrata Extract, Potassium Azeloyl Diglycinate, Opuntia Ficus-Indica Stem Extract, Melia Azadirachta Leaf Extract, Leuconostoc/Radish Root Ferment Filtrate, Moringa Oleifera Seed Oil, Alaria Esculenta Extract, Adenosine Phosphate, PEG-10 Phytosterol, Tribehenin, Hydrolyzed Vegetable Protein, Sorbitan Olivate, Sodium Gluconate, Zinc Gluconate, Copper Gluconate, Magnesium Aspartate, Cetearyl Olivate, Isoamyl Cocoate, Caprylic/Capric Triglyceride, Polyglyceryl-10 Caprylate/Caprate, Microcrystalline Cellulose, C12-15 Alkyl Benzoate, Xanthan Gum, Pentylene Glycol, Butylene Glycol Stearate, Phenoxyethanol, Potassium Sorbate, Ethylhexylglycerin
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinEthylhexyl Palmitate is created from 2-ethylhexyl alcohol and palmitic acid. It is a fatty acid ester.
The fatty acid content of Ethylhexyl Palmitate makes it an emollient. Emollients help soften and hydrate your skin by trapping moisture within.
Ethylhexyl Palmitate is also used to help improve the texture of cosmetics. It helps other ingredient dissolve in products and help disperse ingredients more evenly. In fact, it is commonly used to evenly mix sunscreen ingredients such as avobenzone and ethylhexyl triazone. It can also help stabilize the fragrances in a product as a fragrance fixative.
Ethylhexyl Palmitate can be used to substitute mineral oil.
Learn more about Ethylhexyl PalmitateThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Isoamyl Laurate is created from isoamyl alcohol and lauric acid. It is an emollient and traps moisture underneath.
This ingredient helps give products a silky feel and is considered a silicone alternative.
This ingredient may not be fungal acne safe.
Learn more about Isoamyl LaurateWe don't have a description for Prunus Serotina Fruit Extract yet.
Almond/Borage/Linseed/Olive Acids/Glycerides is an antioxidant and isn't fungal acne safe.
Medicago Sativa Extract is derived from Alfalfa. It contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Alfalfa is also known as lucerne in the UK, South Africa, and the oceania countries. Ancient Greece and Rome used this plant to feed livestock.
Sesamum Indicum Seed is an exfoliant.
Hydrolyzed Eruca Sativa Leaf is an antioxidant.
Sclerocarya Birrea Seed Oil is the oil expressed from the seeds of the Marula plant. In South Africa, Marula is called "an elephant's favorite treat".
Marula seed oil is a non-fragrant oil. It is rich in fatty acids, such as oleic, linoleic, palmitic, stearic, and more. These fatty acids help hydrate the skin.
Other components of marula seed oil include vitamin E and antioxidants such as flavonoids.
Due to the fatty acid content, this ingredient may not be fungal-acne safe.
Learn more about Sclerocarya Birrea Seed OilWe don't have a description for Hydrolyzed Algae Extract yet.
Palmitoyl Hexapeptide-12 is a synthetic peptide made with glycine, histidine, lysine, and palmitic acid.
The sequence of this peptide matches that of elastin, a key protein that plays a role in how firm our skin is.
Due to its palmitic acid base, this ingredient may not be fungal-acne safe.
Learn more about Palmitoyl Hexapeptide-12Palmitoyl Dipeptide-10 is a synthetic peptide with skin conditioning properties.
According to a manufacturer, this peptide also offers antioxidant protection to reduce oxidative damage to cells. Specifically, it prevents glycation to reduce AGEs.
Why is this pretty cool?
AGEs stands for advanced glycation end products. It's when proteins and lipids are damaged from sugar exposure, contributing to premature aging.
Learn more about Palmitoyl Dipeptide-10Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateCeramide NG is a type of Ceramide. The NG stands for a sphinganine base.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here: Ceramide AP Ceramide EOP Ceramide NP
Learn more about Ceramide NgHelianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.
Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.
These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.
Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.
Sunflowers are rich in vitamin E.
Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.
Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Helianthus Annuus Seed OilWe don't have a description for Cocoyl Proline yet.
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolAllantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseWe don't have a description for Eclipta Prostrata Extract yet.
Potassium Azeloyl Diglycinate (PAD) comes from the condensation of azelaic acid mixed with glycine.
This ingredient has similar properties to azelaic acid; it can help reduce sebum production and soothe skin. PAD also inhibits tyrosinase activity to help brighten skin. Tyrosinase is an enzyme that controls melanin production.
A study from 2023 found 5% PAD combined with nicotinamide (a form of niacin) effectively reduced melanin production after 6 weeks.
Several studies from the 2010's also show PAD to be effective in alleviating symptoms of Rosacea.
Though this ingredient is considered a gentle active, higher amounts may result in irritation.
Unlike azelaic acid, this ingredient is water-soluble. This property makes it easier to formulate into skincare products.
Learn more about Potassium Azeloyl DiglycinateThis ingredient comes from the stem of the Prickly Pear cactus. The stem is rich in polyphenols, a potent source of antioxidants. It is anti-aging and soothing properties.
Prickly Pear stem is made up mostly of water (85%). The rest is composed of skin nourishing compounds: protein, fiber, fatty acids, simple sugars, Vitamin C, and some minerals.
Polyphenols help mitigate the effects of aging. Studies show polyphenols protect the skin from oxidative stress, UV-induced damage, and inflammation.
Prickly pear is often compared to Aloe.
Learn more about Opuntia Ficus-Indica Stem ExtractMelia Azadirachta Leaf Extract is extract from the neem plant.
The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.
Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc.
Leuconostoc comes from lactic acid.
This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.
Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).
Learn more about Leuconostoc/Radish Root Ferment FiltrateMoringa Oleifera Seed Oil is the oil expressed from the seeds of Moringa oleifera plant. It is more commonly known as Moringa seed oil.
Moringa seeds have antioxidant, anti-inflammatory, and skin hydrating properties. These seeds are rich in oils, proteins, monounsaturated fats, and tocopherols.
As an emollient, moringa seed oil helps trap moisture in the skin by creating a film on top. This helps keep your skin hydrated and soft.
Many compounds in moringa seed oil are antioxidant and anti-inflammatory. These compounds include Vitamin E. , catechins, ferulic acid, and more.
Another compound found in Moringa seed oil is oleic acid.
Moringa trees are native to the Himalayan mountains.
This ingredient may not be fungal-acne safe.
Learn more about Moringa Oleifera Seed OilAlaria Esculenta Extract is derived from a brown seaweed called badderlocks.
Alaria Esculenta Extract has antioxidant and hydrating properties.
Adenosine Phosphate is an antioxidant and helps soothe skin.
We don't have a description for PEG-10 Phytosterol yet.
Tribehenin comes from glycerin and behenic acid.
It is used as an emollient, or moisturizer. Emollients form a thin barrier on skin to prevent moisture from escaping.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about TribeheninWe don't have a description for Hydrolyzed Vegetable Protein yet.
Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.
Due to its olive oil base, this ingredient may not be fungal-acne safe.
Learn more about Sorbitan OlivateThis is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.
It is mainly used to stabilize oil and butter formulations from going bad. Sodium gluconate is a humectant, pH regulator, and chelating agent.
Chelating agents help neutralize unwanted metals from affecting the formulation.
Sodium gluconate is water-soluble.
Learn more about Sodium GluconateZinc gluconate has antibacterial and wound healing properties. It is particularly effective against fighting inflammatory acne.
This ingredient is the zinc salt of the PHA gluconic acid. PHAs are gentle cousins to AHAs.
This ingredient is a copper salt known for its wound healing properties.
Our bodies use copper to help stabilize our skin's collagen and elastin. Its also an essential for superoxide dismutase, an enzyme with strong antioxidant properties.
Copper has wound healing properties due to its role in creating new blood vessels and tissue repair.
Learn more about Copper GluconateWe don't have a description for Magnesium Aspartate yet.
Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
As an emulsifier, it is used to prevent oils and waters from separating. It can also
Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.
Learn more about Cetearyl OlivateIsoamyl Cocoate isn't fungal acne safe. It can be bad for dry skin.
This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideWe don't have a description for Polyglyceryl-10 Caprylate/Caprate yet.
Microcrystalline Cellulose is another name for refined wood pulp. It is used as an emulsifier and mattifying ingredient. As an emulsifier, it helps keep ingredients together.
C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.
C12-15 Alkyl Benzoate is an emollient and texture enhancer. Due to its solubility, it is often used in sunscreens to help evenly distribute active ingredients.
As an emollient, C12-15 Alkyl Benzoate helps soften and hydrate your skin. Emollients create a film on your skin that traps moisture within.
This ingredient has been reported to cause eye irritation.
Learn more about C12-15 Alkyl BenzoateXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolWe don't have a description for Butylene Glycol Stearate yet.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
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Where it's from
Paula's Choice is a American brand
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published July 13, 2020