La Roche-Posay Toleriane Ultra Soothing Repair Moisturizer Versus innisfree Collagen Peptide Firming Ampoule Cream
This barrier-repair moisturizer is formulated around Squalane and Butyrospermum Parkii Butter to strengthen the skin barrier and calm redness.
This anti-aging moisturizer is formulated around Niacinamide and Copper Tripeptide-1 to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningIsocetyl Stearate
EmollientSqualane
EmollientButyrospermum Parkii Butter
Skin ConditioningDimethicone
EmollientGlycerin
HumectantAluminum Starch Octenylsuccinate
AbsorbentPentylene Glycol
Skin ConditioningPEG-100 Stearate
SurfactantGlyceryl Stearate
EmollientCetyl Alcohol
EmollientSodium Hydroxide
BufferingAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningToluene Sulfonic Acid
SurfactantDimethiconol
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCitric Acid
BufferingWater, Isocetyl Stearate, Squalane, Butyrospermum Parkii Butter, Dimethicone, Glycerin, Aluminum Starch Octenylsuccinate, Pentylene Glycol, PEG-100 Stearate, Glyceryl Stearate, Cetyl Alcohol, Sodium Hydroxide, Acetyl Dipeptide-1 Cetyl Ester, Toluene Sulfonic Acid, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Citric Acid
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantSqualane
EmollientMethyl Trimethicone
Skin ConditioningPentaerythrityl Tetraethylhexanoate
EmollientDibutyl Adipate
EmollientSucrose Polystearate
Emollient1,2-Hexanediol
Skin ConditioningGlyceryl Stearate
EmollientSea Water
HumectantNiacinamide
SmoothingDipalmitoyl Hydroxyproline
Skin ConditioningCetearyl Alcohol
EmollientGlyceryl Stearate Citrate
EmollientLactobacillus Ferment Lysate
Skin ConditioningPalmitic Acid
EmollientHydrogenated Polyisobutene
EmollientStearic Acid
CleansingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingXanthan Gum
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingDextrin
AbsorbentHyaluronic Acid
HumectantHydrolyzed Extensin
Skin ConditioningSimmondsia Chinensis Seed Oil
EmollientPentylene Glycol
Skin ConditioningSodium Metaphosphate
BufferingGlyceryl Caprylate/Caprate
EmollientPolyglyceryl-10 Laurate
Skin ConditioningTromethamine
BufferingEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningCaprylyl Glycol
EmollientArtemisia Vulgaris Oil
PerfumingSorbitan Isostearate
EmulsifyingHydrogenated Lecithin
EmulsifyingTheobroma Cacao Seed Extract
AntioxidantSodium Hyaluronate
HumectantSantalum Album Oil
MaskingPropanediol
SolventMannitol
HumectantAchillea Millefolium Extract
CleansingMyristic Acid
CleansingArachidic Acid
CleansingGlycine Max Polypeptide
Skin ConditioningAcrylates/Stearyl Methacrylate Copolymer
Emulsion StabilisingHydrolyzed Hyaluronic Acid
HumectantTremella Fuciformis Sporocarp Extract
AntioxidantDisodium EDTA
Sodium Hyaluronate Crosspolymer
HumectantCopper Tripeptide-1
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningTocopherol
AntioxidantAcetyl Heptapeptide-4
HumectantCeramide NP
Skin ConditioningAcetyl Tetrapeptide-11
Skin ConditioningSoluble Collagen
HumectantSodium Acetylated Hyaluronate
HumectantAcetyl Hexapeptide-8
HumectantSodium Hydroxide
BufferingHexapeptide-9
Skin ConditioningAcetyl Octapeptide-3
HumectantWater, Glycerin, Butylene Glycol, Squalane, Methyl Trimethicone, Pentaerythrityl Tetraethylhexanoate, Dibutyl Adipate, Sucrose Polystearate, 1,2-Hexanediol, Glyceryl Stearate, Sea Water, Niacinamide, Dipalmitoyl Hydroxyproline, Cetearyl Alcohol, Glyceryl Stearate Citrate, Lactobacillus Ferment Lysate, Palmitic Acid, Hydrogenated Polyisobutene, Stearic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dextrin, Hyaluronic Acid, Hydrolyzed Extensin, Simmondsia Chinensis Seed Oil, Pentylene Glycol, Sodium Metaphosphate, Glyceryl Caprylate/Caprate, Polyglyceryl-10 Laurate, Tromethamine, Ethylhexylglycerin, Adenosine, Caprylyl Glycol, Artemisia Vulgaris Oil, Sorbitan Isostearate, Hydrogenated Lecithin, Theobroma Cacao Seed Extract, Sodium Hyaluronate, Santalum Album Oil, Propanediol, Mannitol, Achillea Millefolium Extract, Myristic Acid, Arachidic Acid, Glycine Max Polypeptide, Acrylates/Stearyl Methacrylate Copolymer, Hydrolyzed Hyaluronic Acid, Tremella Fuciformis Sporocarp Extract, Disodium EDTA, Sodium Hyaluronate Crosspolymer, Copper Tripeptide-1, Acetyl Tetrapeptide-2, Tocopherol, Acetyl Heptapeptide-4, Ceramide NP, Acetyl Tetrapeptide-11, Soluble Collagen, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Sodium Hydroxide, Hexapeptide-9, Acetyl Octapeptide-3
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water