Heveblue Phyton Squa Hyal Blue Gel Cream Versus SKIN1004 Madagascar Centella Poremizing Light Gel Cream

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

The water carries small amounts of the tree's volatile compounds that give it a soft and woody scent.

Most of the published skin research is related to the essential oil or leaf extract rather than this water form; these cell and mice studies should antioxidant, antibacterial, and anti-inflammatory effects.

This ingredient only contains a small amount of these beneficial compounds but can still provide some soothing.

The Hinokitiol compound in this water is also antifungal against Malassezia; this can make it a great option for those with fungal acne.

However, those with fragrance sensitivity should patch test.

Fun fact: The Japanese 'Hinoki' Cypress tree is traditionally used to build shrines and temples.

This ingredient contains a group of yellow pigments called curcuminoids (mostly curcumin) that give it genuine antioxidant and anti-inflammatory activity in skin.

Reviews of topical clinical studies have found turmeric/curcumin to be generally well-tolerated and useful across conditions like eczema and mild inflammation.

One thing working in its favor is that curcumin barely penetrates; in lab skin-permeation testing, the curcuminoids mostly stayed in the outermost layer of skin. This is a good thing because its soothing and antioxidant activity is a surface-level job anyway.

At this time, industry data shows there's no single "correct" cosmetic percentage. It's used across a wide range depending on the product and varies from tiny fractions of a percent up to a few percent.

Allergy-wise, curcumin is a documented (but uncommon) contact allergen. It can also cross react with related plants, so anyone with a turmeric/ginger/cinnamon allergy or reactive skin should patch test first.

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

Traditional Iranian folk medicine uses Lavender extract to help treat inflammation.

Lavender extract may have a scent.

It contains linalool, a known allergen. However, lavender extract contains less linalool than lavender essential oil.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!