Dr. Denese SkinScience Hemp Super Serum Versus Paula's Choice 1% Retinol Treatment - US
Updated on March 20, 2024
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 12 ingredients in common
Cool Features
They both contain ceramides, peptides, retinoid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
What's Inside
They both contain oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr. Denese SkinScience Hemp Super Serum 27 ingredients
Paula's Choice 1% Retinol Treatment 53 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Dr. Denese SkinScience Hemp Super Serum 27 ingredients
Paula's Choice 1% Retinol Treatment 53 ingredients
Key Ingredients
Benefits
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Dimethicone
Emollient
Cyclopentasiloxane
Emollient
Caprylyl Methicone
Skin Conditioning
Dimethicone Crosspolymer
Emulsion StabilisingCannabis Sativa Seed Oil
Emollient
Tetrahexyldecyl Ascorbate
Antioxidant
Hydroxypinacolone Retinoate
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Palmitoyl Hexapeptide-12
Skin Conditioning
Palmitoyl Hexapeptide-14
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Melatonin
Antioxidant
Ceramide Ng
Skin Conditioning
Bisabolol
Masking
Zingiber Officinale Root Extract
MaskingHydroxymethoxyphenyl Decanone
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialPolysilicone-11
Ethoxydiglycol
HumectantCaprylic/Capric Triglyceride
MaskingSorbitan Laurate
Emulsifying
C18-36 Acid Glycol Ester
EmollientC18-36 Acid Triglyceride
EmollientTribehenin
Emollient
PEG-10 Phytosterol
EmulsifyingDimethyl Isosorbide
SolventDimethicone, Cyclopentasiloxane, Caprylyl Methicone, Dimethicone Crosspolymer, Cannabis Sativa Seed Oil, Tetrahexyldecyl Ascorbate, Hydroxypinacolone Retinoate, Tocopheryl Acetate, Palmitoyl Hexapeptide-12, Palmitoyl Hexapeptide-14, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Melatonin, Ceramide Ng, Bisabolol, Zingiber Officinale Root Extract, Hydroxymethoxyphenyl Decanone, C12-15 Alkyl Benzoate, Polysilicone-11, Ethoxydiglycol, Caprylic/Capric Triglyceride, Sorbitan Laurate, C18-36 Acid Glycol Ester, C18-36 Acid Triglyceride, Tribehenin, PEG-10 Phytosterol, Dimethyl Isosorbide
Water
Skin ConditioningDimethicone
Emollient
Glycerin
Humectant
Butylene Glycol
Humectant
Isononyl Isononanoate
EmollientCastor Isostearate Succinate
Skin Conditioning
Glyceryl Stearate
Emollient
C12-15 Alkyl Benzoate
AntimicrobialDimethicone Crosspolymer
Emulsion StabilisingPEG-33
HumectantPolysorbate 20
Emulsifying
Behenyl Alcohol
Emollient
PEG-100 Stearate
Pentaerythrityl Tetraisostearate
Emollient
Polymethylsilsesquioxane
Tetrahexyldecyl Ascorbate
Antioxidant
Retinol
Skin Conditioning
Ceramide Ng
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Sodium Hyaluronate
Humectant
Dipotassium Glycyrrhizate
Humectant
Glycyrrhiza Glabra Root Extract
Bleaching
Avena Sativa Kernel Extract
Abrasive
Arctium Lappa Seed Oil
Emollient
Salix Alba Extract
Skin ConditioningGlycine Soja Sterols
Emollient
Lecithin
EmollientAllantoin
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Hydrolyzed Soy Protein
HumectantSorbitan Laurate
Emulsifying
Acetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Disodium EDTA
Hydroxyethylcellulose
Emulsion StabilisingPalmitoyl Tripeptide-1
Skin Conditioning
Sodium Hydroxide
BufferingTribehenin
Emollient
Caprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningPEG-75 Shea Butter Glycerides
Emulsifying
PPG-12/Smdi Copolymer
EmollientPEG-10 Phytosterol
EmulsifyingPEG-8 Dimethicone
Emulsifying
PEG-14
HumectantMagnesium Aluminum Silicate
AbsorbentArachidyl Glucoside
EmulsifyingArachidyl Alcohol
EmollientSclerotium Gum
Emulsion StabilisingCarbomer
Emulsion StabilisingPhenoxyethanol
Preservative
Benzoic Acid
Masking
Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Arachidyl Alcohol, Sclerotium Gum, Carbomer, Phenoxyethanol, Benzoic Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetatePalmitoyl Hexapeptide-12 is a synthetic peptide made with glycine, histidine, lysine, and palmitic acid.
The sequence of this peptide matches that of elastin, a key protein that plays a role in how firm our skin is.
Due to its palmitic acid base, this ingredient may not be fungal-acne safe.
Learn more about Palmitoyl Hexapeptide-12Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Ceramide NG is a type of Ceramide. The NG stands for a sphinganine base.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here: Ceramide AP Ceramide EOP Ceramide NP
Learn more about Ceramide NgC12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.
C12-15 Alkyl Benzoate is an emollient and texture enhancer. Due to its solubility, it is often used in sunscreens to help evenly distribute active ingredients.
As an emollient, C12-15 Alkyl Benzoate helps soften and hydrate your skin. Emollients create a film on your skin that traps moisture within.
This ingredient has been reported to cause eye irritation.
Learn more about C12-15 Alkyl BenzoateSorbitan Laurate is created from lauric acid and derivatives from sorbitol. It is an emulsifier.
Tribehenin comes from glycerin and behenic acid.
It is used as an emollient, or moisturizer. Emollients form a thin barrier on skin to prevent moisture from escaping.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about TribeheninWe don't have a description for PEG-10 Phytosterol yet.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Dr. Denese SkinScience Hemp Super Serum 27 ingredients
Paula's Choice 1% Retinol Treatment 53 ingredients
Reviews
Here's what our community thinks
Dr. Denese SkinScience Hemp Super Serum 27 ingredients
Paula's Choice 1% Retinol Treatment 53 ingredients
Love it
My favorite retinol. Been using it for a year and never had any bad reactions (be sure to follow instructions like starting slow). It's a bit pricey but worth it
