Updated on June 13, 2024
Overview
What they are
These products are both vegan, cruelty-free, and reef safe serums. They have a total of 7 ingredients in common
Suited For
They're both likely to be good for dry skin, brightening skin, sensitive skin, oily skin and dark spots
Free From
They both do not contain any parabens, silicones or sulfates
What's Inside
They both contain fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
AXIS - Y Spot The Difference Blemish Treatment 47 ingredients
ISOI Blemish Care Serum 32 ingredients
At a glance
Click on any of the items below to learn more
AXIS - Y Spot The Difference Blemish Treatment 47 ingredients
ISOI Blemish Care Serum 32 ingredients
Notable Ingredients
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Benefits
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Concerns
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Aloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.
Laminaria Japonica Extract comes from a kelp more commonly known as 'sweet kelp'. It is commonly eaten in Japan, Korea, and China.
Eclipta Prostrata Leaf Extract comes from the false daisy plant. False daisy contains antioxidant compounds such as flavonoids.
Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Ficus Carica Fruit Extract comes from the fruit known as the fig. Figs are rich in antioxidants and helps hydrate the skin.
5 Benefits
Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
Good for Oily Skin
Melaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.
Rosmarinus Officinalis Leaf Oil is oil expressed from the leaves of the rosemary plant.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
C12-14 Pareth-12 is created from a mixture of synthetic C12-14 alcohols that have about 12 moles of ethylene oxide.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Fructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
4-Terpineol is the main component of tea tree oil. It has antibacterial, antioxidant, and anti-inflammatory properties.
Glycyrrhiza Glabra Rhizome/Root is a plant material derived from the dried rhizomes and roots of the Licorice, Glycyrrhiza glabra L., Leguminosae
Not safe for Fungal Acne
Moringa Oleifera Seed Oil is the oil expressed from the seeds of Moringa oleifera plant. It is more commonly known as Moringa seed oil.
7 Benefits 2 Concerns
Glycolic Acid is arguably the most famous AHA with a ton of research to back up its benefits.
Preservative 5 Benefits 4 Concerns
Salicylic Acid (also known as beta hydroxy acid or BHA) is one of the most well-known ingredients for treating skin that struggles with blackheads and acne. It helps to exfoliate both the skin's surface and pores, and also acts as an anti-inflammatory agent.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Water, Glycerin, Propanediol, 1,2-Hexanediol, Glycereth-26, Niacinamide, Caprylic/Capric Triglyceride, Aloe Barbadensis Leaf Extract, Althaea Rosea Flower Extract, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Centella Asiatica Extract, Ficus Carica Fruit Extract, Ulmus Davidiana Root Extract, Amaranthus Caudatus Seed Extract, Camellia Sinensis Leaf Extract, Monarda Didyma Leaf Extract, Hydrangea Macrophylla Leaf Extract, Mentha Aquatica Extract, Sasa Quelpaertensis Extract, Melaleuca Alternifolia Leaf Extract, Melia Azadirachta Leaf Extract, Eclipta Prostrata Extract, Cinnamomum Camphora Leaf Extract, Cryptomeria Japonica Leaf Extract, Pinus Pinaster Bark/Bud Extract, Rosmarinus Officinalis Leaf Oil, Hydrogenated Lecithin, Chamaecyparis Obtusa Water, Trehalose, Octyldodeceth-16, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, C12-14 Pareth-12, Butylene Glycol, Xanthan Gum, Disodium EDTA, Ceramide NP, Fructooligosaccharides, Beta-Glucan, Hydrolyzed Hyaluronic Acid, 4-Terpineol, Glycyrrhiza Glabra Rhizome/Root, Moringa Oleifera Seed Oil, Glycolic Acid, Salicylic Acid, Ethylhexylglycerin
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Rosa Damascena Flower Water comes from the Damask rose. It is a dilluted version of the Rose Essential oil.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
5 Concerns
Alcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.
Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.
2 Benefits
Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.
Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
Rosa Damascena Flower Oil is an essential oil made from the Damask Rose. It is often used as a fragrance in cosmetics.
Hippophae Rhamnoides Fruit Extract comes from the seabuckthorn berry. This berry is native to Asia and has been used in traditional medicine for centuries.
This extract comes from the Cabbage Palm, AKA the Açaí berry! It has skin soothing, antioxidant, and anti-aging properties.
Vaccinium Macrocarpon Fruit Extract comes from the cranberry fruit. Vaccinium Macrocarpon is the North American species of cranberries native to eastern Canada.
Houttuynia Cordata Extract is more commonly known as Heart Leaf, Fish Mint, or Chameleon plant.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
Salix Alba Bark Extract comes from the white willow tree, which is native to Europe and Central Asia.
Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
2 Benefits
Calendula Officinalis Flower Extract comes from the common Marigold plant. This ingredient is a skin conditioner.
Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
Paeonia Suffruticosa Root Extract comes from the Paeonia Suffruticosa plant known as the Peony.
Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
EU Allergen
Citronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
EU Allergen
Geraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Water, Rosa Damascena Flower Water, Glycerin, Alcohol, Betaine, Arbutin, Trehalose, Rosa Damascena Flower Oil, Arctostaphylos Uva-Ursi Leaf Extract, Rhodiola Rosea Root Extract, Hippophae Rhamnoides Fruit Extract, Euterpe Oleracea Fruit Extract, Vaccinium Angustifolium Fruit Extract, Phyllanthus Emblica Fruit Extract, Vaccinium Macrocarpon Fruit Extract, Sophora Flavescens Root Extract, Houttuynia Cordata Extract, Xanthan Gum, Allantoin, Panthenol, Adansonia Digitata Leaf Extract, Castanea Crenata Shell Extract, Salix Alba Bark Extract, Centella Asiatica Extract, Butylene Glycol, 1,2-Hexanediol, Calendula Officinalis Flower Extract, Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, Glycyrrhiza Glabra Root Extract, Citronellol, Geraniol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about Glycerin1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.
Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
AXIS - Y Spot The Difference Blemish Treatment 47 ingredients
ISOI Blemish Care Serum 32 ingredients
Reviews
Here's what our community thinks
AXIS - Y Spot The Difference Blemish Treatment 47 ingredients
RyannCook
This is the best spot treatment I've ever used. I have mild acne, mostly due to environmental factors like alcohol or sugar intake or sometimes...
This is the best spot treatment I've ever used. I have mild acne, mostly due to environmental factors like alcohol or sugar intake or sometimes hormones. It always clears up a spot almost overnight.
Seraphim
After 2 weeks I could see the size of my blackheads and pores was visibly reduced. I only used it in my night routine. Once a week I also used...
After 2 weeks I could see the size of my blackheads and pores was visibly reduced. I only used it in my night routine. Once a week I also used "Salicylic Acid Shrink Pores Serum" (AHA+BHA), which might have contributed to the shrinkage of my pores. I'm satisfied with the product, although the packaging might be small for everyday use. After a month of using it in my evening routine, I've already used up one third of the 15ml bottle, but that's nothing unusual. To clarify, I use 3 drops on my entire face.
