Merzy Perfect Shield No-Wash Treatment Balm
A leave-in treatment with 74 ingredients, including exfoliants and peptides.
Overview
What it is
Leave-in treatment with 74 ingredients that contains exfoliants and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, parabens or sulfates
Fun facts
Merzy is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Glycerin
HumectantWater
Skin ConditioningDimethicone
EmollientMyristyl Alcohol
EmollientAvena Sativa Protein Extract
Skin ConditioningSteartrimonium Chloride
PreservativeParfum
MaskingPropylene Glycol
Humectant1,2-Hexanediol
Skin ConditioningDipropylene Glycol
HumectantHydroxyacetophenone
AntioxidantGuar Hydroxypropyltrimonium Chloride
Skin ConditioningDisodium EDTA
Polyquaternium-7
Sodium Benzoate
MaskingHydrolyzed Soy Protein
HumectantHydrolyzed Rice Protein
Skin ConditioningHydrolyzed Sesame Protein
Skin ConditioningHydrolyzed Barley Protein
Skin ConditioningButylene Glycol
HumectantBrassica Oleracea Italica Seed Oil
EmollientCarthamus Tinctorius Seed Oil
MaskingCamellia Sinensis Seed Oil
HumectantDaucus Carota Sativa Seed Oil
EmollientHelianthus Annuus Seed Oil
EmollientMoringa Oleifera Seed Oil
EmollientOlea Europaea Fruit Oil
MaskingRibes Nigrum Seed Oil
EmollientSolanum Lycopersicum Seed Oil
EmollientVitis Vinifera Seed Oil
EmollientEthylhexylglycerin
Skin ConditioningAcetyl Hexapeptide-8
HumectantHexapeptide-9
Skin ConditioningNonapeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningMagnesium PCA
HumectantCopper Tripeptide-1
Skin ConditioningSerine
MaskingSucrose
HumectantGlycine
BufferingCalcium Chloride
AstringentSea Salt
AbrasiveAlanine
MaskingMagnesium Chloride
Threonine
Histidine
HumectantAspartic Acid
MaskingValine
MaskingProline
Skin ConditioningDipotassium Phosphate
BufferingLysine
Skin ConditioningLeucine
Skin ConditioningTyrosine
MaskingIsoleucine
Skin ConditioningMagnesium Citrate
Skin ConditioningGlucosamine Hcl
Glutamic Acid
HumectantPhenylalanine
MaskingArginine
Masking1-Methylhydantoin-2-Imide
Skin ConditioningAsparagine
MaskingCitrulline
Skin ConditioningMethionine
Skin ConditioningTaurine
BufferingTryptophan
MaskingFormic Acid
PreservativeCysteine
AntioxidantGlutamine
Skin ConditioningBenzyl Salicylate
PerfumingLimonene
PerfumingLinalool
PerfumingCinnamyl Alcohol
PerfumingGlycerin, Water, Dimethicone, Myristyl Alcohol, Avena Sativa Protein Extract, Steartrimonium Chloride, Parfum, Propylene Glycol, 1,2-Hexanediol, Dipropylene Glycol, Hydroxyacetophenone, Guar Hydroxypropyltrimonium Chloride, Disodium EDTA, Polyquaternium-7, Sodium Benzoate, Hydrolyzed Soy Protein, Hydrolyzed Rice Protein, Hydrolyzed Sesame Protein, Hydrolyzed Barley Protein, Butylene Glycol, Brassica Oleracea Italica Seed Oil, Carthamus Tinctorius Seed Oil, Camellia Sinensis Seed Oil, Daucus Carota Sativa Seed Oil, Helianthus Annuus Seed Oil, Moringa Oleifera Seed Oil, Olea Europaea Fruit Oil, Ribes Nigrum Seed Oil, Solanum Lycopersicum Seed Oil, Vitis Vinifera Seed Oil, Ethylhexylglycerin, Acetyl Hexapeptide-8, Hexapeptide-9, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Magnesium PCA, Copper Tripeptide-1, Serine, Sucrose, Glycine, Calcium Chloride, Sea Salt, Alanine, Magnesium Chloride, Threonine, Histidine, Aspartic Acid, Valine, Proline, Dipotassium Phosphate, Lysine, Leucine, Tyrosine, Isoleucine, Magnesium Citrate, Glucosamine Hcl, Glutamic Acid, Phenylalanine, Arginine, 1-Methylhydantoin-2-Imide, Asparagine, Citrulline, Methionine, Taurine, Tryptophan, Formic Acid, Cysteine, Glutamine, Benzyl Salicylate, Limonene, Linalool, Cinnamyl Alcohol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeMyristyl Alcohol is type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
As an emollient, myristyl alcohol hydrates the skin by trapping moisture in.
Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols.
The FDA allows "alcohol-free" products to contain fatty alcohols.
Learn more about Myristyl AlcoholWe don't have a description for Avena Sativa Protein Extract yet.
Steartrimonium Chloride is a preservative.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of âFRAGRANCEâ or âPARFUMâ according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPropylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene Glycol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the âgoodâ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenoneThis ingredient is derived from guar gum. It is a skin conditioning agent that creates a thin, breathable film to reduce water loss during cleansing.
This leaves the skin feeling soft rather than stripped and also contributes to a creamier lather.
Due to the large molecule size, this ingredient is unlikely to penetrate skin.
Learn more about Guar Hydroxypropyltrimonium ChlorideDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAPolyquaternium-7 is a light to clear colored liquid. It is commonly found in haircare products for its film-forming and anti-static properties.
According to a manufacturer, it is a non-paraben and specially developed for negatively charged surfactant systems. This makes it a great hairstyle holder and helps to improve wet hair detangling without adding buildup.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateHydrolyzed Soy Protein is a vegan protein made to mimic hydrolyzed collagen. It is created from soy, or glycine soja.
This ingredient is a humectant, meaning it helps hydrate the skin by binding to water. According to a manufacturer, it is also a great hair conditioner.
Read more about hydrolyzed collagen here.
Learn more about Hydrolyzed Soy ProteinHydrolyzed Rice Protein is protein extracted from rice. This ingredient is rich in antioxidants and peptides.
Studies show this ingredient may help with blocking the melanin creation process when skin is exposed to UV.
We don't have a description for Hydrolyzed Sesame Protein yet.
We don't have a description for Hydrolyzed Barley Protein yet.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolBrassica Oleracea Italica Seed Oil is from the broccoli plant.
Broccoli is rich in antioxidants such as Beta-carotene, vitamin A, and vitamin C.
Broccoli is also rich in fatty acids such as oleic and linoleic acids. This makes it an effective moisturizer. Its high Omega 3, Omega 6, and Omega 9 content make it an effective moisturizer.
Learn more about Brassica Oleracea Italica Seed OilCarthamus Tinctorius Seed Oil comes from the seeds of the safflower plant. It is a skin conditioning agent that helps soften skin and keep it hydrated.
This seed oil has an unusual fatty acid profile: it is one of the highest linoleic acid plant oils out there (~55-77%). It also has low amounts of oleic acid, and this high-linoleic/low-oleic ratio gets people excited.
Linoleic acid helps maintain skin barrier integrity and is a building block for the ceramides in your stratum corneum. Notably, people with acne tend to have lower linoleic acid in their skin lipids as well (and this gets worse as acne gets more severe).
Overall, it's a lightweight, fast-absorbing oil that has a long safety track record. Lab testing has found it to be non-irritating for skin or eyes.
The Malassezia yeast can metabolize the fatty acids in this oil to grow; therefore this ingredient may not be fungal acne safe.
Learn more about Carthamus Tinctorius Seed OilCamellia Sinensis Seed Oil is the oil expressed from the seeds from the tea plant. This is the same plant we get green, black, and oolong tea from.
Camellia Sinensis Seed Oil is rich in oleic acid. This makes it an effective moisturizer. By drawing moisture to the skin, Camellia Oleifera Seed Oil helps keep your skin hydrated.
Other components of Camellia Sinensis Seed Oil includes Vitamin E and polyphenols. These are antioxidants that may help slow down the signs of aging. Antioxidants help fight free-radicals, or unstable molecules that can damage our skin cells.
Camellia Sinensis Seed Oil also has anti-inflammatory properties.
The seed oil comes from the dried kernels of the plant.
Learn more about Camellia Sinensis Seed OilDaucus Carota Sativa Seed Oil is the oil obtained from the seed of the edible carrot. The oil is created by steaming and distilling the seeds of the plant.
Carrot Seed Oil has hydrating, anti-inflammatory, and antioxidant properties.
As an emollient, carrot seed oil creates a thin film on the skin. This film prevents moisture from escaping, keeping your skin hydrated. Carrot seed oil has a soothing effect and can help alleviate inflammation.
As an antioxidant, carrot seed oil may help reduce the signs of aging. Antioxidants are able to neutralize free-radical molecules, or molecules that can damage our skin's cells and DNA.
Emerging studies show the alpha-pinene and carotol content give carrots antibacterial and antifungal properties. However, this is dependent on the amount of each compound. More studies are needed.
Carrot Seed Oil is not carrot oil. Carrot oil is created by mixing parts of the carrot in a carrier oil, such as coconut oil.
Learn more about Daucus Carota Sativa Seed OilHelianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Learn more about Helianthus Annuus Seed OilMoringa Oleifera Seed Oil is a lightweight oil from the seeds of the Moringa oleifera tree. In cosmetics, it's an emollient that forms a light film to slow water loss and soften skin.
Its fatty acid composition is dominated by oleic acid (70-78%), with smaller amounts of behenic, palmitic, and stearic acids (this profile is actually pretty similar to olive oil).
Notably, this ingredient is oxidatively stable for an oil and resists going rancid as fast as other oils.
A small, in vivo study on 32 participants found a cream with this ingredient increased skin hydration with no reported skin irritation. It also found the tocopherol content gave it some antioxidant activity as well.
One thing to flag for fungal acne:
Because this oil is so high in oleic acid, Malassezia can use it as a food source and this ingredient may not be fungal acne safe.
For everyone else, this ingredient is well-tolerated and nourishing with a good safety track record.
Learn more about Moringa Oleifera Seed OilThis ingredient is also known as olive oil. It has been used in skincare for centuries and science largely backs up its reputation as a nourishing emollient.
The main components of olive oil are oleic acid (55-83%), linoleic acid (3.5-20%), and palmitic acid (7-20%). Oleic acid promotes skin regeneration and helps regulate inflammatory responses.
Squalene is also naturally present in olive oil and exhibits moisturizing and antioxidant properties.
The polyphenols in olive oil also show anti-aging promise; one clinical study found a measurable improvement in skin appearance after 30 days of topical serum use.
Just be aware that applying olive oil directly to skin can weaken the barrier and cause redness. One study with volunteers found even people without sensitive skin experienced a significant reduction in stratum corneum integrity and induced mild erythema.
It's best to use this ingredient as part of a carefully crafted formula (instead of putting it on skin directly from the bottle).
Because it has a 2-3 on the comedogenic scale, it is a moderate risk for acne-prone skin. However, the overall formulation of a product matters more than a few ingredients with comedogenic ratings.
This ingredient may not be fungal acne safe because of the oleic and palmitic acid content. These fall within the C11-24 fatty acid range that the Malassezia yeast can metabolize to grow.
Overall, olive oil is a well-studied and nourishing skincare ingredient.
Learn more about Olea Europaea Fruit OilRibes Nigrum Seed Oil is oil from the seeds of Black Currant. A more common name for this ingredient is Black Currant Seed Oil.
Black Currant Seed Oil contains a high amount of omega-6 and omega-3 fatty acids. It also contains linoleic acid.
Black currant berries contain anthocyanins, an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Black currant berries also contain Vitamin E and fatty acids. It can help soften the skin.
Learn more about Ribes Nigrum Seed OilSolanum Lycopersicum Seed Oil is an oil and isn't fungal acne safe.
Vitis Vinifera Seed Oil comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.
The components of grape seeds have many skin benefits. Research has found it to be antimicrobial and anti-inflammatory. It also contains many potent antioxidants such as Vitamin E , Vitamin C, proanthocyanidins, polyphenols, flavonoids, and anthocyanins. Proanthocyanidin has been shown to help even out skin tone.
Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.
The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.
Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.
The fatty acids of grape seed oil give it emollient properties. Emollients help soothe and soften your skin by creating a film. This film traps moisture within, keeping your skin hydrated.
Learn more about Vitis Vinifera Seed OilEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinAcetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itâs often referred to as a âBotox-likeâ ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itâs not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnât a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Hexapeptide-9 is a signaling peptide that is made to mimic a fragment found naturally in collagen IV and XVII.
It is classified as a matrikine peptide and works by telling your skin cells (especially fibroblasts) to ramp up collagen and hyaluronic acid production.
In-vitro studies show it can enhance epidermal regeneration, boost synthesis of collagen types I, III, and IV, and improved markers of skin differentiation.
Think of skin differentiation like this: your skin cells are born at the bottom and slowly travel up to the surface as they "grow up". As they move up, they start producing specific proteins that make your skin do its job well. Two of these proteins are keratin (it makes your skin tough) and filaggrin (it breaks apart into tiny molecules to keep your skin hydrated). So Hexapeptide-9 has shown to help skin cells grow up properly and make stronger, more hydrated skin.
A manufacturer also reports increased collagen production by 117% and hyaluronic acid production by 267%.
Just know much of the published data comes from manufacturer-sponsored studies. There is a recent clinical trial showing promising anti-aging results but the evidence base is still growing.
Generally, this ingredient is well-tolerated and there's no harm in using it as a supportive ingredient in your routine.
Learn more about Hexapeptide-9Nonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
This ingredient is the magnesium salt of PCA (Pyrrolidone Carboxylic Acid). It is a great skin hydrator for the top layers of skin.
PCA is a natural humectant, meaning it draws water from the air to your outer layer of skin.
One study found magnesium ions improved skin hydration in the outer layer of skin, or the stratum corneum. However, it did not improve TEWL, or the transepidermal water loss. The TEWL is an indicator of how healthy your skin barrier function is. This study primarily looked at healthy skin with intact skin barrier.
Learn more about Magnesium PCACopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesnât turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isnât backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.
In skincare, sucrose is a humectant and can be a mild exfoliant.
Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.
Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.
In some products such as body scrubs, sucrose is used as an gentle exfoliant.
The term 'sucrose' comes from the french word for sugar, 'sucre'.
Learn more about SucroseGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Calcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.
This ingredient is highly soluble in water, acetic acid, and ethanol.
There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.
Learn more about Calcium ChlorideSea salt has abrasive or exfoliation properties. It can sensitize and dry out the skin.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Magnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.
This ingredient can also play a role in soothing the skin and supporting normal skin function.
Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong âactiveâ ingredient on its own.
Learn more about Magnesium ChlorideThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineProline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineDipotassium Phosphate is an inorganic salt. This just means it has a different structure than organic salts. It is a stabilizing and pH adjusting ingredient.
This ingredient is soluble in water.
Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineWe don't have a description for Leucine yet.
Tyrosine is one of the amino acids used to create protein. It plays a role in melanin production.
A study from 2012 found tyrosine to show promising results in restoring skin volume.
Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
We don't have a description for Magnesium Citrate yet.
We don't have a description for Glucosamine Hcl yet.
Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidPhenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineWe don't have a description for 1-Methylhydantoin-2-Imide yet.
Asparagine is one building block of all proteins in our body. It is an antioxidant and may help with anti-aging.
Antioxidants help fight free-radicals, or molecules that may damage our skin cells.
We don't have a description for Citrulline yet.
Methionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineTaurine is an amino acid that is found in human skin as an osmolyte. An osmolyte is a small molecule that cells use to hold onto water and stay comfortable under stressful conditions.
In skin cell studies, taurine accumulation helps cells maintain hydration in low-humidity environments. Some dermatology research on osmolytes also link taurine to barrier support. Research also suggests that osomolyte systems can be disrupted in photoaged skin.
One animal study reported tropical taurine improved barrier function and collagen signaling, while another one found oral taurine can lessen UVB-related damage. It is important to note that evidence for taurine in skincare is mostly preclinical, meaning further studies are needed.
Learn more about TaurineWe don't have a description for Tryptophan yet.
Formic Acid is a preservative.
Cysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.
Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.
Glutamine is an amino acid (a small building block your body uses to make proteins). It has skin conditioning properties and helps skin feel comfortable.
Think of glutamine as a quiet support player in your skincare. Your skinâs outer layer (stratum corneum) needs two things to stay healthy: a strong barrier and enough moisture.
Part of what helps hold water in the skin is something called Natural Moisturizing Factors (NMF). These include amino acids or the same building blocks that make up proteins in your body.
Since glutamine is an amino acid, it falls into the âbarrier-friendly, skin-conditioningâ category. Thatâs why youâll usually find it in hydrating and soothing formulas.
There's some experimental evidence that glutamine can calm inflammation-related skin reactions when applied topically in a contact-dermatitis model. However, it's not the same as a proven eczema fix.
Learn more about GlutamineBenzyl Salicylate is a solvent and fragrance additive. It is an ester of benzyl alcohol and salicylic acid. This ingredient can be naturally found in some plants and plant extracts.
In fragrances, Benzyl Salicylate may be a solvent or a fragrance component. In synthetic musk scents, it is used as a solvent. For floral fragrances such as lilac and jasmine, it is used as a fragrance component. The natural scent of Benzyl Salicylate is described as "lightly-sweet, slightly balsamic".
While Benzyl Salicylate has been associated with contact dermatitis and allergies, emerging studies show it may not be caused by this ingredient alone.
However, this ingredient is often used with fragrances and other components that may cause allergies. It is still listed as a known allergen in the EU. We recommend speaking with a professional if you have concerns.
Another study from 2021 shows Benzyl Salicylate may have anti-inflammatory properties.
Learn more about Benzyl SalicylateLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolCinnamyl Alcohol is derived from cinnamon and balsam. It oxidizes quickly when exposed to air.
Cinnamyl Alcohol is a known EU allergen. This means it may cause an allergic reaction when applied to the skin. The EU requires this ingredient to be labeled separately on an ingredients list.
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Read more about us· Updated July 25, 2025 • Added by anemone