Dr. Denese SkinScience Advanced SPF 30 Defense Day Cream Ingredients Explained
Published on December 12, 2022
Overview
What it is
Day moisturizer with 53 ingredients that contains exfoliants, hyaluronic acid, retinoid, Vitamin C and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
Fun facts
Dr. Denese SkinScience is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
Ingredient List (53)
Water, Dimethicone, Octyldodecyl Neopentanoate, Cyclopentasiloxane, Coconut Alkanes, Peg-10 Dimethicone, Montmorillonite, Butylene Glycol, Polymethylsilsesquioxane, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone Crosspolymer, Bis-Diglyceryl Polyacyladipate-2, Sodium PCA, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Lactate, Arginine, Aspartic Acid, PCA, Phospholipids , Melanin, Triethoxycaprylylsilane, Glycine, Alanine, Serine, Pentylene Glycol, Valine, Proline, Threonine, Isoleucine, Leuconostoc/Radish Root Ferment Filtrate, Retinyl Palmitate, Ascorbyl Palmitate, Tocopheryl Acetate, Calcium Pantothenate, Histidine, Phenylalanine, Polysilicone-11, Sodium Chloride, Coco-Caprylate/Caprate, Disteardimonium Hectorite, Glyceryl Laurate, Peg/Ppg-18/18 Dimethicone, Polyhydroxystearic Acid, Cetyl Peg/Ppg-10/1 Dimethicone, Xanthan Gum, Dipotassium Glycyrrhizate, Silica, Disodium EDTA, Phenoxyethanol, CI 77492, CI 77491, CI 77499
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Ingredient Info
Alcohol Free
This product is free of harsh alcohols 🎉
Contains Silicon
Ingredients in this product that are types of silicon:
Fragrance Free
This product is free of fragrances 🎉
Sulfate Free
This product is free of sulfates 🎉
Paraben Free
This product is free of parabens 🎉
Oil Free
This product is free of oils 🎉
Not Malassezia Safe
Ingredients in this product that are not malassezia safe:
Reef Safe
This product is free of ingredients that damage reefs 🎉
EU Allergen Free
This product is free of EU allergens 🎉
Non Vegan
This product is not vegan 😥
Cruelty Free
This product is cruelty-free 🎉
Ingredients Overview
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterDimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.
We don't have a description for Octyldodecyl Neopentanoate.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneCoconut Alkanes is created from the fatty-acids of coconut oil. It is volatile, meaning it evaporates from the skin.
Coconut Alkanes is an emollient and solvent. As an emollient, it helps keep skin soft and hydrated. Solvents help distribute and mix other ingredients. This ensures a more even consistency.
Coconut Alkanes may not be fungal-acne safe.
Learn more about Coconut AlkanesPeg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.
According to the manufacturer, acidic formulations decrease the stability of this ingredient. It works best in neutral or near neutral formulations.
Montmorillonite is a clay (aluminomagnesium silicate) with strong absorption properties. It has a similar pH to skin.
This clay is named after Montmorillon in France.
Learn about other types of clay, such as Kaolin, Bentonite, or Fuller's Earth.
Learn more about MontmorilloniteButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Polymethylsilsesquioxane is a silicone used as a film forming agent.
When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.
Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.
If you have concerns about using this ingredient, we recommend speaking with a professional.
Learn more about PolymethylsilsesquioxaneDimethicone/Vinyl Dimethicone Crosspolymer is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
Like other silicones, Dimethicone/Vinyl Dimethicone Crosspolymer helps condition the skin by creating a barrier. In this sense, it can act as an emollient and trap moisture in.
Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
Bis-Diglyceryl Polyacyladipate-2 is lipid-based synthetic skin-conditioning agent. As an emollient, it helps soften and hydrate the skin.
Emollients create a barrier on the skin to trap moisture in.
Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
Sodium PCA is a has conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCASodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateHydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidSodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.
Sodium Lactate is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin.
It also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
Our NMF is formed from amino acids, lactic acid, sugars, minerals, peptides, and electrolytes. As we age, our NMF naturally depletes. Other sources of NMF depletion include harsh and drying ingredients such as denatured alcohol. Sodium lactate can help replenish our NMF, leading to more hydrated and plump skin.
High percentages of Sodium Lactate can have an exfoliating effect.
Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateArginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Antioxidants help mitigate damage from free-radical molecules. These are molecules that originate from external sources such as pollution, cigarette smoke, or the sun.
Learn more about Aspartic AcidPCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin. Due to their hygroscopic nature, they act as humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in. This ingredient is non-occlusive.
Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.
Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.
Some types of phospholipids:
Learn more about PhospholipidsTriethoxycaprylylsilane is a silicone used to bind and stabilize ingredients.
As an emulsifier, it helps prevent ingredients from separating. This can help elongate the shelf life of products.
Triethoxycaprylylsilane is often used to coat mineral sunscreens ingredients to help give a better feel. It also helps reduce oxidative stress in sunscreens.
Learn more about TriethoxycaprylylsilaneGlycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.
Glycine helps keep skin hydrated and reduce signs of aging. Amino acids help transport moisture throughout our skin; glycine already plays a role in helping keep our skin moisturized.
As collagen is made up of glycine and other amino acids, it is believed Glycine may help our skin produce more collagen. Collagen helps keep skin plump and firm.
Learn more about GlycineAlanine is an amino acid and is already found in the human body.
Alanine has antioxidant properties and can help with anti-aging.
Alanine is used by fibrous proteins such as collagen, elastin, and keratin. These three help make a strong skin barrier. Having a healthy skin barrier leads to more plump and youthful skin.
Learn more about AlanineSerine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.
Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.
Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.
Learn more about SerinePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolWe don't have a description for Valine.
Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.
Proline is one of the building blocks for producing collagen. As we age, our bodies produce less collagen. Collagen helps the skin look plump and firm.
In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.
Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.
Learn more about ProlineThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Threonine is vital for creating collagen and elastin. Collagen and elastin support youthful and firm skin. Our bodies decrease collagen production naturally with age.
Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Learn more about ThreonineWe don't have a description for Isoleucine.
Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. Leuconostoc comes from lactic acid. This bacteria is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).
Leuconostoc/Radish Root Ferment Filtrate has antimicrobial properties and helps prevent the growth of bacteria in a product.
It is believed the preservation property comes from salicylic acid and ammonium salt, neither of which are involved in the fermentation process.
Learn more about Leuconostoc/Radish Root Ferment FiltrateRetinyl palmitate is a form of retinoid. It is created from palmitic acid and retinol.
This ingredient has antioxidant and exfoliating properties. Like other types of retinols, retinyl palmitate increases cell turnover. Removing dead skin cells and encouraging the growth of new ones improves skin tone and unclogs pores. This in turn promotes brighter looking skin and even skin texture.
As an antioxidant, retinyl palmitate helps neutralize free-radical molecules. These molecules have the potential to damage skin cells. Thus, antioxidants may help with anti-aging.
Retinyl palmitate can be good for be good for oily skin by helping to unclog pores. However, it may not be good for dry skin and fungal acne.
After using this product, you should follow up with sunscreen.
This ingredient is often added to low-fat milk to increase the levels of Vitamin A.
Learn more about Retinyl PalmitateAscorbyl Palmitate is created by combining pure Vitamin C and palmitic acid. It is an antioxidant and helps reduce hyperpigmentation.
Antioxidants help fight free-radical molecules, or molecules that may break down skin cells. Antioxdants help reduce signs of aging.
Ascorbyl Palmitate is a stable version of Vitamin C, meaning it does not disintegrate when exposed to sunlight. However, studies show it does not penetrate skin as well as pure Vitamin C.
Read more about other types of Vitamin C:
Learn more about Ascorbyl PalmitateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCalcium Pantothenate is calcium salt from Vitamin B5. It can be naturally found in plants and animals.
Calcium Pantothenate is a potent antioxidant. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. This may help reduce the signs of aging.
Our bodies use Calcium Pantothenate for various metabolic functinos. These functions include metabolizing carbohydrates, proteins, and fatty acids.
Learn more about Calcium PantothenateWe don't have a description for Histidine.
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
Phenylalanine is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineWe don't have a description for Polysilicone-11.
Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.
This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
There is much debate on whether this ingredient is comedogenic. The short answer - comedogenic ratings don't tell the whole story. Learn more about comegodenic ratings here.
The concensus about this ingredient causing acne seems to be divided. Research is needed to understand if this ingredient does cause acne.
Scrubs may use salt as the primary exfoliating ingredient.
Learn more about Sodium ChlorideCoco-Caprylate/Caprate is created from fatty coconut alcohol, caprylic acid, and capric acid.
It is a lightweight emollient. Emollients create a thin barrier on the skin to trap moisture in. This helps keep your skin hydrated and soft.
Once applied, Coco-Caprylate/Caprate is absorbed quickly and leaves a silky feel.
Coco-Caprylate/Caprate may not be fungal acne safe.
Learn more about Coco-Caprylate/CaprateDisteardimonium Hectorite comes from the clay mineral named hectorite. It is used to add thickness to a product.
It can also help stabilize a product by helping to disperse other ingredients.
Hectorite is a rare, white clay mineral.
Learn more about Disteardimonium HectoriteGlyceryl Laurate isn't fungal acne safe.
Peg/Ppg-18/18 Dimethicone is a type of silicone.
Polyhydroxystearic Acid is a soft wax made from castor oil.
It is is a texture thickener, emulsifier, and film-former. Emulsifiers prevent ingredients from separating, such as oils and waters.
Polyhydroxystearic Acid may not be fungal acne safe.
Learn more about Polyhydroxystearic AcidThis ingredient is a high molecular weight silicone. It has emulsifying and skin conditioning properties.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateSilica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.
Silica is present naturally within the skin during collagen production and when reducing inflammation.
Learn more about SilicaDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ci 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77492Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.
Iron III oxides are classified as inorganic chemicals for coloring.
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