Canmake Luster Veil Rouge
A lipstick with 46 ingredients, including retinoid, niacinamide, and exfoliants.
Lipstick with 46 ingredients that contains ceramides, exfoliants, niacinamide, retinoid and Vitamin E
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
C20-24 Alkyl Dimethicone
Skin ConditioningHydrogenated Polyisobutene
EmollientDipentaerythrityl Pentaisostearate
EmollientOctyldodecanol
EmollientCaprylic/Capric Triglyceride
MaskingPhytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate
Skin ConditioningPhytosteryl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningParaffin
Skin ConditioningSynthetic Wax
AbrasiveIsotridecyl Isononanoate
EmollientHydrogenated Coco-Glycerides
EmollientDiisostearyl Malate
EmollientTitanium Dioxide
Cosmetic ColorantMacadamia Ternifolia Seed Oil
EmollientCentella Asiatica Extract
CleansingChitosan
C10-18 Triglycerides
EmollientSynthetic Fluorphlogopite
Polyglyceryl-2 Triisostearate
EmulsifyingMicrocrystalline Wax
Emulsion StabilisingEthylene/Propylene Copolymer
AbrasivePolyglyceryl-2 Diisostearate
EmulsifyingStearalkonium Hectorite
Gel FormingPropylene Carbonate
SolventTocopherol
AntioxidantWater
Skin ConditioningAllantoin
Skin ConditioningNiacinamide
SmoothingGlycerin
HumectantButylene Glycol
HumectantHydrogenated Lecithin
Emulsifying1,2-Hexanediol
Skin ConditioningBrassicasterol
Retinol
Skin ConditioningCholesterol
EmollientPolyglyceryl-10 Laurate
Skin ConditioningCeramide NP
Skin ConditioningAluminum/Magnesium Hydroxide Stearate
Emulsion StabilisingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantPotassium Cetyl Phosphate
EmulsifyingTris(Tetramethylhydroxypiperidinol)Citrate
StabilisingIron Oxides
CI 45410
Cosmetic ColorantCI 15850
Cosmetic ColorantCI 42090
Cosmetic ColorantCI 19140
Cosmetic ColorantC20-24 Alkyl Dimethicone, Hydrogenated Polyisobutene, Dipentaerythrityl Pentaisostearate, Octyldodecanol, Caprylic/Capric Triglyceride, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Paraffin, Synthetic Wax, Isotridecyl Isononanoate, Hydrogenated Coco-Glycerides, Diisostearyl Malate, Titanium Dioxide, Macadamia Ternifolia Seed Oil, Centella Asiatica Extract, Chitosan, C10-18 Triglycerides, Synthetic Fluorphlogopite, Polyglyceryl-2 Triisostearate, Microcrystalline Wax, Ethylene/Propylene Copolymer, Polyglyceryl-2 Diisostearate, Stearalkonium Hectorite, Propylene Carbonate, Tocopherol, Water, Allantoin, Niacinamide, Glycerin, Butylene Glycol, Hydrogenated Lecithin, 1,2-Hexanediol, Brassicasterol, Retinol, Cholesterol, Polyglyceryl-10 Laurate, Ceramide NP, Aluminum/Magnesium Hydroxide Stearate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Potassium Cetyl Phosphate, Tris(Tetramethylhydroxypiperidinol)Citrate, Iron Oxides, CI 45410, CI 15850, CI 42090, CI 19140
Key Ingredients
Benefits
Concerns
Ingredients Explained
C20-24 Alkyl Dimethicone is a type of silicone.
Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
In one study, Hydrogenated Polyisobutene showed better skin hydration levels than Caprylic/Capric Triglyceride. As an emollient, it helps keep your skin soft and hydrated by trapping moisture in.
Hydrogenated Polyisobutene is often used as a mineral oil replacement.
Learn more about Hydrogenated PolyisobuteneWe don't have a description for Dipentaerythrityl Pentaisostearate yet.
Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideThis is a plant-derived ester that functions as a skin conditioner. It's basically a two linoleic acid molecules combined with fatty alcohols.
In practice, it works as a rich emollient that helps reduce moisture loss and give skin a soft appearance.
The phytosterol part of this ingredient brings an added structural bonus: phytosterols are structurally similar to cholesterol so they can fit right into the stratum corneum's lipid matrix to help reinforce the skin barrier.
Due to its molecular structure, this ingredient delivers a cushiony and glossy feeling without being excessively greasy.
It did not produce skin irritation or sensitization in clinical studies, and this ingredient is deemed safe to use in cosmetics at current practices.
Because this ingredient contains C16, C18, and C22 fatty chains, it may not be Malassezia/fungal acne safe. The Malassezia yeast potentially feeds on fatty acids in the C11-C24 range.
Learn more about Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer DilinoleateWe don't have a description for Phytosteryl/Octyldodecyl Lauroyl Glutamate yet.
Paraffin is a solid wax that pulls its weight as an emollient, occlusive, and consistency-booster.
It softens skin and lays down a protective film to slow water loss and gives products a stable body and structure.
The cosmetic grade stuff is highly refined with a solid safety record. The CIR Expert Panel has repeatedly reaffirmed this ingredient to be safe in current practices of use and concentration.
The worry about carcinogenic compounds only applies to industrial grades, not the purified version used in skincare.
Despite its reputation, the highly reformed form is non-comedogenic and doesn't penetrate deeply into skin.
The good news for fungal-acne prone folks: the Malassezia yeast feeds on fatty acids and lipids and paraffin doesn't contain any of these (so there's nothing for the yeast to metabolize). This ingredient is considered fungal acne safe.
Learn more about ParaffinSynthetic Wax is a manufactured hydrocarbon wax. In formulas, it works as an occlusive emollient that helps reduce water loss and improves the spreadability of products.
Research comparing synthetic wax to traditional mineral-derived products found that formulas containing it perform as well for skin hydration.
It is considered non-comedogenic and vegan-friendly.
This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.
Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.
Learn more about Synthetic WaxWe don't have a description for Isotridecyl Isononanoate yet.
Hydrogenated Coco-Glycerides isn't fungal acne safe.
Diisostearyl Malate is an emollient and most often used in lip products. It comes from isostearyl alcohol, a fatty acid, and malic acid, an AHA.
As an emollient, Diisostearyl Malate helps create a thin film on your skin to trap moisture in. This helps keep your skin soft and smooth.
Titanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.
It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).
A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.
They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.
When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.
So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.
TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.
Together, they make a solid broad-spectrum system.
TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.
It's also unlikely to cause the "eye sting" some chemical filters are known for.
The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).
Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.
TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:
TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.
In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.
TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.
The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.
There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.
For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).
There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.
The science is still developing and it's a space worth watching rather than packing over.
However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.
Learn more about Titanium DioxideThis ingredient is also known as Macadamia Seed Oil. It's an emollient with a fatty acid profile that closely mirrors the skin's own lipid makeup.
The palmitoleic acid content is especially notable as it's somewhat rare in plant oils. Palmitoleic acid is something your skin already makes naturally. It helps keep cell membranes structured and plays a role in fighting off harmful microbes.
This palmitoleic content is also part of why macademia seed oil absorbs quickly and doesn't leave much of a greasy residue.
It also contains oleic acid, linoleic acid, and phytosterols that can help reduce redness.
In vitro research has shown the oil to have meaningful antioxidant activity, protect fats in the skin from oxidative damage, and slow down the enzyme that breaks down hyaluronic acid.
A 2024 clinical study found it effective at improving skin hydratino and reducing wrinkle appearance when formulated into nanoemulsions.
Because it carries oleic acid (C18) and palmitic acid (C16), this ingredient may not be fungal acne safe. This is because the Malassezia yeast metabolizes in the C11-24 chain length range.
You'll also see this ingredient listed as: Macadamia Integrifolia Seed Oil .
These two oils are identical in composition and M. ternifolia is an older INCI naming convention for the edible macadamia nut while M. integrifolia is the species actually cultivated for oil production. Both names refer to the same oil.
Learn more about Macadamia Ternifolia Seed OilCentella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.
That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.
These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.
Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.
Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.
Here is the short version of what they do in the skin:
So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.
Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:
Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.
Centella is one of the most easygoing actives out there.
It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.
On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.
Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.
But as with any new active, a patch test is still a smart move for very reactive skin.
Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).
The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).
In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.
Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractWe don't have a description for Chitosan yet.
C10-18 Triglycerides is a skin conditioning and texture-enhancer.
It is created from glycerin and a mixture of C10-18 fatty acids.
This ingredient improves spreadability and helps thicken a product.
According to manufacturers, it usually comes from vegetable-based saturated fatty acids. Common bases for this ingredient are coconut oil, palm kernel oil, or both.
Due to the melting point being close to skin temperature, it is usually used in lip products.
Triglycerides are a main component of fat in the human body.
Learn more about C10-18 TriglyceridesSynthetic Fluorphlogopite is the synthethic version of mica. It consists of fluorine, aluminum and silicate.
Synthetic Fluorphlogopite is used to add volume to products.
It is considered non-irritating on the skin.
Learn more about Synthetic FluorphlogopitePolyglyceryl-2 Triisostearate is a plant-derived emulsifier and pigment-dispersing agent with a non-sticky skin feel.
It helps products glide on smoothly and prevents oil and water from separating in a formula, making it suitable for sunscreen and makeup formulations.
The EU inventory of cosmetics has no use restrictions on this ingredient and it is considered well-tolerated.
This ingredient may not be fungal acne safe because it is derived from isostearic acid.
Learn more about Polyglyceryl-2 TriisostearateMicrocrystalline Wax is derived from petroleum through a de-oiling process, then highly refined and purified before use in cosmetics.
In skincare formulations, it is used to improve texture and create a smooth, even consistency. It also helps stabilize products by preventing ingredients from separating.
Ethylene/Propylene Copolymer is an exfoliant.
Polyglyceryl-2 Diisostearate isn't fungal acne safe.
Stearalkonium Hectorite is a clay-derived ingredient used to thicken a product and help create a gel-like texture.
This ingredient is a solvent. It helps dissolve active ingredients and alter the texture of products.
Propylene Carbonate is commonly used in makeup and with clay, such as montmorillonite or bentonite.
Studies show this ingredient to be safe for cosmetics. When it is undiluted, it can cause skin irritation. (It is always diluted in skincare and makeup). This ingredient is water-soluble.
Propylene Carbonate is created from propylene glycol and carbonic acid.
Learn more about Propylene CarbonateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated Lecithin1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Brassicasterol is a plant-based sterol. It naturally occurs in marine algae, fish, and rapeseed oil.
The compound has low water solubility and is considered harmful in contact with skin (H312, Acute dermal toxicity warning) according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
Retinol is one of the most studied anti-aging ingredients in skincare (and for good reason!).
It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells.
That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid.
Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process.
Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid; your skin does the work gradually. This also explains where Retinol sits in the retinoid family.
Here is the retinoid family ranked roughly by strength: Retinyl Esters (like Retinyl Palmitate) < Retinol < Retinaldehyde < Retinoic Acid.
Retinoid activity increases in that order, while tolerance runs in reverse; retinyl esters are the gentlest and retinoic acid the most irritating.
The more conversion steps an ingredient needs, the gentler (and slower) it tends to be, so Retinol lands in a nice middle spot. It's more effective than the esters, gentler than prescription options.
Once it becomes Retinoic Acid, it binds to receptors inside your cells' nuclei (called RARs and RXRs). These receptor pairs bind to specific DNA motifs called retinoic acid response elements and act like switches that turn certain genes on or off.
In practice, this means a few things happen in a formula. It:
That last two are worth a closer look.
A study that tested Retinol directly (not just prescription Retinoic Acid) found that four weeks of retinol thickened the epidermis and switched on the genes for Collagen I and Collagen III, with more procollagen I and III showing up in the skin. And after twelve weeks, facial wrinkles were visibly reduced.
Retinoids more broadly stimulate the skin's synthesis of hyaluronan and other glycosaminoglycans, part of what gives skin a plumper, more hydrated look over time.
So even the gentler OTC form is doing real structural work (not just sitting on the surface).
It's also worth knowing Retinol isn't only a wrinkle ingredient; it can help with uneven tone, dark spots, rough texture, and the look of pores as well because it speeds up turnover and influences pigment.
The research backs this up as well.
A pooled analysis of six clinical studies found that 0.1% stabilized retinol improved all signs of photoaging versus vehicle as early as week 4 and through 12 weeks, with only a few mild cases of irritation.
Another study comparing concentrations found that 0.3% and 1% Retinol were similarly effective at remodeling photodamaged skin, but 0.3% caused fewer adverse reactions when used daily (a useful reminder that more isn't always better).
Retinol is about tenfold less potent than Retinoic Acid. This is why it works as a gentler, non-prescription option that builds results over time.
Typical concentrations range from 0.1-1%, with 0.1% to 0.3% being a well-supported sweet spot for visible benefits with good tolerability.
One quirk worth mentioning: Retinol is famously unstable.
It's highly sensitive to light and oxygen, and UV exposure breaks it down into a range of degradation products.
Real-world testing bears this out, with retinoid content in some products dropping anywhere from 0% to 80% after six months at room temperature, and even more at higher temperatures.
This is why good formulations lean on opaque, air-tight packaging (think tubes and pumps, not clear jars) and often "encapsulate" the Retinol to shield it.
Signs of oxidation include your product turning yellow or smelling "off". Keeping it somewhere cool and dark, and using it up within a few months of opening helps it stay effective.
The most common side effects are mild and temporary: usually some dryness, redness, or light peeling as your skin adjusts. These tend to settle with consistent and lower-frequency use.
Like all retinoids, Retinol works best with nightly use, a good moisturizer, and daytime sunscreen.
The "ramp up" method works well: start with Retinol once a week to give your skin time to adjust, which keeps irritation low. Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.
One safety note: topical Retinoids aren't recommended during pregnancy or breastfeeding. Systemic absorption from creams is low but because high oral vitamin A is a known teratogen and topical safety data are limited, most clinicians recommend stopping retinoids when pregnant or trying to conceive.
Learn more about RetinolCholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Learn more about CholesterolPolyglyceryl-10 Laurate is a cleansing agent and emulsifier.
It rounds up dirt, oil, and grime, so they can be rinsed off easily as a cleanser.
On the emulsifier side, it keeps your formula smooth and well-mixed by playing peacekeeper for ingredients that don't naturally get along (like oil and water).
Because it has a C12 (lauric acid) fatty acid chain, this ingredient can potentially feed the Malassezia yeast that causes fungal acne. The Malassezia yeast prefers esters with C11-C24 fatty acids.
This ingredient is an ester of lauric acid and Polyglycerin-10.
Learn more about Polyglyceryl-10 LaurateCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPWe don't have a description for Aluminum/Magnesium Hydroxide Stearate yet.
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
It is used to help stabilize other antioxidants or prevent the color from changing in a product.
As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.
This ingredient is oil-soluble.
Learn more about Pentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamatePotassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.
Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.
Learn more about Potassium Cetyl PhosphateWe don't have a description for Tris(Tetramethylhydroxypiperidinol)Citrate yet.
This ingredient is a combination of red, black, and yellow iron oxide pigments. This combination of colors is usually found in foundation, because it results in a "skin" color.
The EU typically uses CI numbers for colorants when applicable, such as CI 77489. In the US, iron oxides are regulated as color additives and "iron oxides" is the most commonly used name in US cosmetic practice.
A 2021 paper looked at skincare formulations containing iron oxides and found that they reduced transmission of blue light when measured optically. In simple terms, the pigment particles helped block or scatter part of the visible light spectrum in lab testing and the authors suggest this could translate into better protection against blue-light-related skin effects.
There is also clinical and experimental research showing that tinted products containing iron oxides can reduce visible light-induced pigmentation:
Please note, whether a product reduces visible or blue light depends on things like:
In the EU's CosIng database, iron oxides are only listed as a colorant. CosIng groups ingredients by their main cosmetic role, such as colorant, preservative, or UV filter.
Though studies say iron oxides can "attenuate blue light", they're describing an optical property and not an officially recognized cosmetic function.
So CosIng isn’t contradicting the research. It’s just classifying iron oxides by what they officially are: pigments that add color.
Learn more about Iron OxidesCI 45410 is a synthetic red-pigment and dye.
It often goes by both Red 28 or Red 27; manufacturers label both ingredients as CI 45410.
This dye is commonly found in makeup because it imparts a vivid color. Some types of this dye change color based on pH level and interaction with moisture:
Your skin has a natural pH of around 4.5 - 5.5.
According to the FDA, CI 45410 is not permitted for use in eye products.
Red 27 is a flourescein dye and commonly used as a fluorescent tracer in medicine.
Learn more about CI 45410Ci 15850 is the pigment color red. It is an azo dye and created synthetically.
Azo dyes need to be thoroughly purified before use. This allows them to be more stable and longer-lasting.
This ingredient is common in foundations, lipsticks, and blushes. This color is described as brown/orangey red.
It has many secondary names such as Red 6 and Red 7. According to a manufacturer, Red 6 usually contains aluminum.
Learn more about CI 15850Ci 42090 is a synthetic dye created from petroleum. It is used to give a bright blue color to cosmetics, medicine, and food.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Learn more about CI 19140Reviews
No written reviews yet. Be the first to review this product.
Recent searches
Search reviews by skin type, ingredient, or keyword.
Where it's from
Canmake is a Japanese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated December 9, 2025 • Added by anemone