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Some By Mi Retinol Intense Reactivating Serum Versus Differin Adapalene Gel 0.1% Acne Treatment

Serum
Facial Treatment
Korean Brand South Korea
American Brand United States

Updated on August 07, 2024

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne and anti aging

Free From

They both do not contain any harsh alcohols, common allergens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol Intense Reactivating Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Cyclohexasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Disliked Full details ->
Dicaprylyl Carbonate Emollient, Skin Conditioning

Dicaprylyl Carbonate comes from carbonic acid and caprylyl alcohol, a fatty alcohol. It is an emollient and gives skin a velvet feel. The sources of Dicaprylyl Carbonate may be synthetic or from animals.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Methylpropanediol Solvent

Methylpropanediol is a synthetic solvent and humectant.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Hydrogenated Polyisobutene Emollient, Skin Conditioning
1 / 2

Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.

1 Com. / 2 Irr.
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Piper Methysticum Leaf/Root/Stem Extract Skin Conditioning

We don't have a description for Piper Methysticum Leaf/Root/Stem Extract.

Unknown Full details ->
Centella Asiatica Extract Cleansing, Skin Conditioning, Smoothing
Helps reduce Skin Redness IconHelps reduce irritation Icon
2 Benefits

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Panax Ginseng Berry Extract Skin Conditioning, Skin Protecting

We don't have a description for Panax Ginseng Berry Extract.

Glycyrrhiza Glabra Root Extract Bleaching, Emollient, Skin Conditioning
Good for Dark Spots Icon
Good for Dark SpotsGood for Dark Spots Icon

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

Ficus Carica Fruit Extract Humectant

Ficus Carica Fruit Extract comes from the fruit known as the fig. Figs are rich in antioxidants and helps hydrate the skin.

Centella Asiatica Leaf Extract Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Centella Asiatica Root Extract Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Centella Asiatica Root Extract can help to reduce redness.

Melaleuca Alternifolia Leaf Extract Perfuming, Skin Conditioning
Fragrance IconGood for Oily Skin Icon
FragranceFragrance Icon Good for Oily SkinGood for Oily Skin Icon

Melaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.

Artemisia Capillaris Extract

We don't have a description for Artemisia Capillaris Extract.

Eclipta Prostrata Extract Skin Conditioning

We don't have a description for Eclipta Prostrata Extract.

Melia Azadirachta Leaf Extract Skin Conditioning

Melia Azadirachta Leaf Extract is extract from the neem plant.

Elaeis Guineensis Oil Emollient
Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Elaeis Guineensis Oil comes from the African Palm tree. This tree is native to Western and Southwestern Africa.

Very Disliked Full details ->
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Bakuchiol Antimicrobial, Antioxidant, Emollient
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots IconHelps brighten skin Icon
AntioxidantAntioxidant Icon 3 Benefits

Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.

Palmitic Acid Emollient, Emulsifying
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Palmitic Acid is a fatty acid found in our skin. In cosmetics, it is usually derived from palm oil. It is a cleanser, emollient, and emulsifier.

2 Com. / 0 Irr.
Very Disliked Full details ->
Sodium Polyacrylate Absorbent, Emollient, Emulsion Stabilising

Sodium Polyacrylate is the sodium salt of polyacrylic acid.

Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Polyquaternium-51 Skin Conditioning

Polyquaternium-51 is a polymer salt. It helps hydrate the skin by creating a film on top. This film traps moisture in, keeping your skin soft and hydrated.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Cetyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

2 Com. / 2 Irr.
Very Disliked Full details ->
BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant and preservative.

Very Disliked Full details ->
Collagen Moisturising, Skin Conditioning
Helps with Anti-Aging Icon
Helps with Anti-AgingHelps with Anti-Aging Icon

Collagen is the most abundant type of structural protein found in your body. It is an effective skin moisturizer.

Myristic Acid Cleansing, Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon
2 Concerns

Myristic Acid is a saturated fatty acid. It is naturally found in milk fat. Other sources include palm oil, coconut oil, and butter fat.

3 Com. / 0 Irr.
Very Disliked Full details ->
BHA Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.

Leuconostoc/Radish Root Ferment Filtrate Antimicrobial

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. Leuconostoc comes from lactic acid. This bacteria is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Ceramide NP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NP is a type of ceramide.

Saccharomyces Ferment Skin Conditioning

Saccharomyces Ferment is created from fermenting and filtering saccharomyces, a group of fungus that includes yeasts. It is a humectant and helps hydrate the skin.

Retinal Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 7 Benefits 3 Concerns

Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Asiaticoside Antioxidant, Skin Conditioning
Antioxidant Icon
AntioxidantAntioxidant Icon

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Glyceryl Polymethacrylate

We don't have a description for Glyceryl Polymethacrylate.

Madecassoside Antioxidant, Skin Conditioning
Antioxidant IconHelps reduce irritation Icon
AntioxidantAntioxidant Icon Helps reduce irritationHelps reduce irritation Icon

Madecassoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Polyglyceryl-10 Oleate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Oleate isn't fungal acne safe.

Disliked Full details ->
Glycolipids Skin Conditioning

We don't have a description for Glycolipids.

Glycine Soja Peptide Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Glycine Soja Peptide is a peptide.

Unknown Full details ->
Resveratrol Antioxidant, Skin Protecting
Antioxidant Icon
AntioxidantAntioxidant Icon

Resveratrol is a famous emerging antioxidant. It is a good alternative for sensitive skin types who cannot tolerate retinoids.

Sucrose Distearate Emollient, Emulsifying, Skin Conditioning
0 / 2 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sucrose Distearate is made up of the sucrose (sugar) esthers of stearic acid. It is an emollient and emulsifier.

0 Com. / 2 Irr.
Disliked Full details ->
Asiatic Acid Skin Conditioning, Stabilising

Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.

Madecassic Acid Skin Conditioning

Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Moringa Oleifera Seed Oil Emollient, Skin Conditioning
Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Moringa Oleifera Seed Oil is the oil expressed from the seeds of Moringa oleifera plant. It is more commonly known as Moringa seed oil.

Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Adapalene Gel 0.1% Acne Treatment
Adapalene
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 2 Benefits 2 Concerns

Adapalene is a type of retinoid and common acne treatment.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Poloxamer 182 Emulsifying

We don't have a description for Poloxamer 182.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Solvent
Disliked

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may deliver a rash when using this ingredient.

Learn more about Propylene Glycol

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Retinol Intense Reactivating Serum
37
10
16
2
liked
mixed
disliked
not rated
Adapalene Gel 0.1% Acne Treatment
2
1
4
1
liked
mixed
disliked
not rated

When to use

320 Routines
3% use in am
97% use in pm
60% use every day
When to use See routines that use it ->
1,942 Routines
8% use in am
92% use in pm
75% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Some By Mi Retinol Intense Reactivating Serum 65 ingredients

4.5 /5
from 2 ratings
Absorbs Well (1) Drying (1) Great Value (1)
YSLDave's avatar

YSLDave

9 months ago · Oily Skin
Review

Great for beginers
if you never used retinol Serum, buy this, is a Great Serum, absorb really quick and is perfect for oily skin

Alaa_ysf's avatar

Alaa Ali

3 months ago · Combination Skin
Review

Every retinol that I have used caused my skin to be irritated and I wasn't able to continue using it, but this one is amazing. It's good for...

Every retinol that I have used caused my skin to be irritated and I wasn't able to continue using it, but this one is amazing. It's good for sensitive skin it's safe to use.

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.8 /5
from 18 ratings
Absorbs Well (5) Works Well (5) Light (4)
BrittBrine's avatar

BrittBrine

9 months ago · Sensitive Skin
Review

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest...

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest time. My skin looks and feels so much better and I've only been using it for about 2-3 months now.

jojoswrld_'s avatar

johari 🪽

7 months ago · Unsure Skin
Review

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin,...

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin, but it clears over time and leaves the skin incredibly firm and smooth. It’s the only not cruelty-free product I use just because it’s benefitted me so greatly and, in my opinion, is indisputably the best prescription-grade retinoid especially for sensitive skin.