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Adapalene

Explained

Adapalene is a third-generation topical retinoid and is best known for treating mild to moderate acne. It’s also commonly as for its brand name, Differin.

Adapalene has some great benefits:

  • Reduces acne by normalizing skin cell turnover and preventing clogged pores.
  • Is less irritating than older retinoids like tretinoin or tazarotene.
  • Is stable in light and air, making it more suitable for daytime use and compatible with benzoyl peroxide.
  • Especially effective for comedonal acne (blackheads and whiteheads).

You can buy over-the-counter adapalene at 0.1% gel strength. Higher concentrations require a prescription.

Oleyl adapalenate is a cosmetic-grade derivative of adapalene that does not require a prescription since it is considered a cosmetic ingredient.

See all 56 products with Adapalene

Users who like it
92%
Users who avoid it
8%

Prevalence

Less common Percentage of products that contain it
0.1%
Top categories
Treatments
Other Skincare
Masks
Position Predominant list placement
Top 25%
Concentration Concentrations we've seen
0% to 1%

References