Missha Time Revolution Night Repair Ampoule 5x Versus Rejuran Advanced Anti-Aging Retinol + C-PDRN Serum
This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging serum is formulated around Retinol and Palmitoyl Tripeptide-38 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Bifida Ferment Lysate
Skin Conditioning
Butylene Glycol
Humectant
1,2-Hexanediol
Skin Conditioning
Glycerin
Humectant
Betaine
Humectant
Propanediol
Solvent
Water
Skin ConditioningChondrus Crispus Extract
Skin Conditioning
Saccharum Officinarum Extract
MoisturisingPentylene Glycol
Skin Conditioning
Niacinamide
Smoothing
Polyquaternium-51
Skin Conditioning
Diethoxyethyl Succinate
SolventSqualane
Emollient
Panthenol
Skin Conditioning
Polyglyceryl-10 Laurate
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Carbomer
Emulsion StabilisingLactobacillus Ferment
Skin Conditioning
Lactobacillus Ferment Lysate
Skin Conditioning
Leuconostoc/Radish Root Ferment Filtrate
Antimicrobial
Lactococcus Ferment
Skin ConditioningLactobacillus/Acerola Cherry Ferment
Skin ProtectingLactobacillus/Soybean Ferment Extract
Skin ConditioningLactobacillus/Punica Granatum Fruit Ferment Extract
Antioxidant
Lactococcus Ferment Lysate
Skin Conditioning
Bifida Ferment Filtrate
Skin Conditioning
Tromethamine
BufferingSolanum Melongena Fruit Extract
Skin ConditioningDaucus Carota Sativa Root Extract
Skin Conditioning
Brassica Oleracea Capitata Leaf Extract
Skin ConditioningBeta Vulgaris Root Extract
Skin ConditioningVaccinium Angustifolium Fruit Extract
Skin Protecting
Ethylhexylglycerin
Skin ConditioningXanthan Gum
EmulsifyingAspergillus Ferment
Skin ConditioningSwiftlet Nest Extract
Skin ConditioningDextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningAdenosine
Skin Conditioning
Citrus Aurantium Bergamia Fruit Oil
Masking
Pelargonium Graveolens Flower Oil
Masking
Citrus Aurantium Dulcis Peel Oil
Masking
Lavandula Angustifolia Oil
Masking
Anthemis Nobilis Flower Oil
Masking
Santalum Album Oil
Masking
Limonene
Perfuming
Disodium EDTA
Sodium Hyaluronate
Humectant
Helianthus Annuus Seed Oil
Emollient
Lupinus Albus Seed Extract
Skin ConditioningTocopherol
Antioxidant
Ceramide NP
Skin Conditioning
Cholesterol
Emollient
Bifida Ferment Lysate, Butylene Glycol, 1,2-Hexanediol, Glycerin, Betaine, Propanediol, Water, Chondrus Crispus Extract, Saccharum Officinarum Extract, Pentylene Glycol, Niacinamide, Polyquaternium-51, Diethoxyethyl Succinate, Squalane, Panthenol, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Carbomer, Lactobacillus Ferment, Lactobacillus Ferment Lysate, Leuconostoc/Radish Root Ferment Filtrate, Lactococcus Ferment, Lactobacillus/Acerola Cherry Ferment, Lactobacillus/Soybean Ferment Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Lactococcus Ferment Lysate, Bifida Ferment Filtrate, Tromethamine, Solanum Melongena Fruit Extract, Daucus Carota Sativa Root Extract, Brassica Oleracea Capitata Leaf Extract, Beta Vulgaris Root Extract, Vaccinium Angustifolium Fruit Extract, Ethylhexylglycerin, Xanthan Gum, Aspergillus Ferment, Swiftlet Nest Extract, Dextrin, Theobroma Cacao Extract, Adenosine, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Citrus Aurantium Dulcis Peel Oil, Lavandula Angustifolia Oil, Anthemis Nobilis Flower Oil, Santalum Album Oil, Limonene, Disodium EDTA, Sodium Hyaluronate, Helianthus Annuus Seed Oil, Lupinus Albus Seed Extract, Tocopherol, Ceramide NP, Cholesterol
Aloe Barbadensis Leaf Juice
Skin Conditioning
Rubus Villosus Fruit Extract
AstringentVaccinium Angustifolium Fruit Extract
Skin Protecting
Morus Nigra Leaf Extract
Skin ConditioningCucumis Sativus Fruit Extract
Emollient
Daucus Carota Sativa Root
Skin ConditioningCalendula Officinalis Flower
Skin Conditioning
Caprylic/Capric Triglyceride
Masking
Citrus Aurantium Dulcis Peel Extract
Emulsion Stabilising
Borago Officinalis Seed Oil
Emollient
Panthenol
Skin Conditioning
Glycerin
Humectant
Argania Spinosa Kernel Oil
Emollient
Sodium Ascorbyl Phosphate
Antioxidant
Allantoin
Skin Conditioning
Hydrolyzed DNA
Skin ConditioningAdenosine
Skin Conditioning
Retinol
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Xanthan Gum
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingCarbomer
Emulsion StabilisingDimethicone
Emollient
1,2-Hexanediol
Skin Conditioning
Ethylhexylglycerin
Skin ConditioningAloe Barbadensis Leaf Juice, Rubus Villosus Fruit Extract, Vaccinium Angustifolium Fruit Extract, Morus Nigra Leaf Extract, Cucumis Sativus Fruit Extract, Daucus Carota Sativa Root, Calendula Officinalis Flower, Caprylic/Capric Triglyceride, Citrus Aurantium Dulcis Peel Extract, Borago Officinalis Seed Oil, Panthenol, Glycerin, Argania Spinosa Kernel Oil, Sodium Ascorbyl Phosphate, Allantoin, Hydrolyzed DNA, Adenosine, Retinol, Palmitoyl Tripeptide-38, Xanthan Gum, Hydroxyethylcellulose, Carbomer, Dimethicone, 1,2-Hexanediol, Ethylhexylglycerin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolThis extract comes from the blueberry native to North America. It has great antioxidant and skin soothing properties.
The antioxidant properties from blueberries come from its polyphenolic and vitamin C content. Polyphenols are a compound famous for their antioxidant properties and are commonly found in fruits.
A 2023 study found blueberries to protect skin from UV-B related inflammation. However, this ingredient should not replace your sunscreen.
Learn more about Vaccinium Angustifolium Fruit ExtractXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
