Versus

MediCube PDRN Pink Collagen Exosome Shot 2000 Versus VT Cosmetics PDRN Reedle Shot 100

Facial Treatment
Facial Treatment
Korean Brand South Korea
Korean Brand South Korea

Updated on February 06, 2025

Overview

What they are

These products are both reef safe facial treatments. They have a total of 23 ingredients in common

Cool Features

They both contain hyaluronic acid, niacinamide, peptides and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, fragrances or parabens

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
PDRN Pink Collagen Exosome Shot 2000

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dipropylene Glycol

Masking

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Sodium Polyacrylate

Absorbent

1,2-Hexanediol

Skin Conditioning

Caprylyl Glycol

Emollient

Cetearyl Olivate

Not safe for Fungal Acne Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Hydrolyzed Sponge

Skin Conditioning

Glyceryl Acrylate/Acrylic Acid Copolymer

Humectant

Ethylhexylglycerin

Skin Conditioning

Calcium Aluminum Borosilicate

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Disodium EDTA

Pvm/Ma Copolymer

Emulsion Stabilising

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Rosa Damascena Callus Extracellular Vesicles

Skin Conditioning

Cyanocobalamin

Skin Conditioning

Sodium Dna

Skin Conditioning

Milk Exosomes

Emollient

Collagen Extract

Skin Conditioning
Helps with Anti-Aging Icon

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Hydrogenated Lecithin

Emulsifying

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

PEG-5 Rapeseed Sterol

Cleansing
Not safe for Fungal Acne Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Ceteth-3

Emulsifying

Ceteth-5

Emulsifying

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Hydrolyzed Elastin

Emollient

Potassium Cetyl Phosphate

Emulsifying

Hydroxypropyltrimonium Hyaluronate

Acetyl Tetrapeptide-5

Humectant
Peptide Icon

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning
PDRN Reedle Shot 100

Water

Skin Conditioning

Dicaprylyl Carbonate

Emollient

Caprylic/Capric Triglyceride

Masking

Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate

Emulsifying
Not safe for Fungal Acne Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Polyglyceryl-4 Isostearate

Emulsifying
Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Butylene Glycol Dicaprylate/Dicaprate

Emollient

Magnesium Sulfate

Sulfate Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Dipropylene Glycol

Masking

Polyurethane-15

1,2-Hexanediol

Skin Conditioning

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Diisostearyl Malate

Emollient

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Synthetic Beeswax

Emulsion Stabilising
Not safe for Fungal Acne Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Ethylhexylglycerin

Skin Conditioning

Hippophae Rhamnoides Fruit Oil

Skin Protecting
Oil IconNot safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Disodium EDTA

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Glutathione

Good for Dark Spots Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Rosa Damascena Callus Extracellular Vesicles

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Panax Ginseng Root Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Sucrose

Humectant

Hexapeptide-9

Skin Conditioning
Peptide Icon

Copper Tripeptide-1

Skin Conditioning
Peptide IconGood for Skin Texture IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Hydroxypropyltrimonium Hyaluronate

Palmitoyl Pentapeptide-4

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Sodium Dna

Skin Conditioning

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Mineral Salts

Skin Conditioning
Can worsen Dry Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Propolis Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing IconHelps fight Acne Icon

Asiaticoside

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Asiatic Acid

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Emulsifying

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Due to its olive oil base, this ingredient may not be fungal-acne safe.

Learn more about Sorbitan Olivate
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

We don't have a description for Rosa Damascena Callus Extracellular Vesicles yet.

Skin Conditioning

Sodium DNA is an emerging anti-aging ingredient.

It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.

The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.

You have probably seen this ingredient in anti-aging skincare. But what is it?

DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.

The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.

PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.

PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.

Studies show PDRN has the following properties:

Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).

When using this ingredient, is is best to ask a brand about the source of their Sodium DNA. You'll want to find products where the Sodium DNA is sourced from fish. Some Sodium DNA is derived from calf / cow thymus.

Learn more about Sodium Dna
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.

Polyglyceryl-10 Laurate may not be fungal acne safe.

Learn more about Polyglyceryl-10 Laurate

This form of hyaluronic acid is produced through fermentation.

According to a manufacturer, it has a positive charge by ionic binding to help moisturize and give hair a smooth feel. This is why you'll find this ingredient in shampoos and body washes.

Skin Conditioning

You might know this ingredients as Matrixyl, a famous peptide.

Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine

This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Thus, Matrixyl may help improve the look of wrinkles.

Read more about other common types of peptides here:

Learn more about Palmitoyl Pentapeptide-4

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hyaluronic Acids help moisturize, soothe, and protect the skin.

Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Humectant, Skin Conditioning

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate Crosspolymer
Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Learn more about Hydrolyzed Sodium Hyaluronate
Skin Conditioning

We don't have a description for Potassium Hyaluronate yet.

When to use

15 Routines
27% use in am
73% use in pm
73% use every day
27 Routines
7% use in am
93% use in pm
74% use every day
When to use See routines that use it ->