

MediCube PDRN Pink Caffeine Overnight Wrapping Mask
A cruelty-free overnight mask that contains hyaluronic acid, niacinamide and peptides.
Overview
What it is
Overnight mask with 28 ingredients that contains hyaluronic acid, niacinamide and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
Fun facts
MediCube is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Glycereth-26
HumectantNiacinamide Glycolate
Skin ConditioningC12-14 Alketh-12
EmulsifyingAllantoin
Skin ConditioningSynthetic Fluorphlogopite
Ethylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningCyanocobalamin
Skin ConditioningRosa Damascena Flower Oil
MaskingAscorbyl Tocopheryl Acetate
Skin ConditioningChondrus Crispus Extract
Skin ConditioningHydrolyzed Sodium Hyaluronate
Skin ConditioningGlutamic Acid
HumectantSodium Hyaluronate
HumectantPotassium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantSodium Hyaluronate Crosspolymer
HumectantAspartic Acid
MaskingSodium Hyaluronate Dimethylsilanol
HumectantSodium Behenoyl/Cocoyl (Arginine/Glutamic Acid/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Threonine/Valine)
CleansingCaprylyl Glycol
EmollientMethionine
Skin ConditioningAcetyl Hexapeptide-8
HumectantCI 77400
Cosmetic ColorantPalmitoyl Tripeptide-1
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningNonapeptide-29 Hexapeptide-8
Glycereth-26, Niacinamide Glycolate, C12-14 Alketh-12, Allantoin, Synthetic Fluorphlogopite, Ethylhexylglycerin, Adenosine, Cyanocobalamin, Rosa Damascena Flower Oil, Ascorbyl Tocopheryl Acetate, Chondrus Crispus Extract, Hydrolyzed Sodium Hyaluronate, Glutamic Acid, Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Aspartic Acid, Sodium Hyaluronate Dimethylsilanol, Sodium Behenoyl/Cocoyl (Arginine/Glutamic Acid/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Threonine/Valine), Caprylyl Glycol, Methionine, Acetyl Hexapeptide-8, CI 77400, Palmitoyl Tripeptide-1, Tripeptide-1, Palmitoyl Pentapeptide-4, Nonapeptide-29 Hexapeptide-8
Key Ingredients
Benefits
Ingredients Explained
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26We don't have a description for Niacinamide Glycolate yet.
We don't have a description for C12-14 Alketh-12 yet.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinSynthetic Fluorphlogopite is the synthethic version of mica. It consists of fluorine, aluminum and silicate.
Synthetic Fluorphlogopite is used to add volume to products.
It is considered non-irritating on the skin.
Learn more about Synthetic FluorphlogopiteEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineCyanocobalamin is the manufactured version of vitamin B12. It has skin soothing, antioxidant, and barrier protecting properties. Topical cyanocobalamin is used to treat skin irritation and atopic dermatitis.
Rosa Damascena Flower Oil is an essential oil made from the Damask Rose. It is often used as a fragrance in cosmetics.
Rose Oil has antibacterial and antioxidant properties due to its terpene, glycoside, flavonoid, anthocyanin, and Vitamin C content.
Other major parts of Rose Oil include citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.
The downsides of this ingredient outweight the positives.
Learn more about Rosa Damascena Flower OilAscorbyl Tocopheryl Acetate can help to reduce redness and reduce large pores.
Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.
The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.
Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.
What's the difference between algae and seaweed? Algae is a broad term that includes seaweed. Not all algae is seaweed.
Learn more about Chondrus Crispus ExtractThis ingredient is created by putting sodium hyaluronate through hydrolysis.
You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.
According to studies, low molecular-weight hyaluronic acid can:
One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.
Hydrolysis is a process of changing a molecule using water or enzymes.
This ingredient is water-soluble.
Learn more about Hydrolyzed Sodium HyaluronateGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWe don't have a description for Potassium Hyaluronate yet.
Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidSodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate CrosspolymerAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
We don't have a description for Sodium Hyaluronate Dimethylsilanol yet.
We don't have a description for Sodium Behenoyl/Cocoyl (Arginine/Glutamic Acid/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Threonine/Valine) yet.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolMethionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineAcetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8We don't have a description for CI 77400 yet.
Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Tripeptide-1 is a peptide. It can help to reduce the effects of aging.
You might know this ingredients as Matrixyl, a famous peptide.
Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Thus, Matrixyl may help improve the look of wrinkles.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Nonapeptide-29 Hexapeptide-8 is a peptide.
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Where it's from
MediCube is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published June 5, 2025 • Added by sabrinaodigie