MEDI-PEEL Premium 2.0 Collagen Naite Thread Neck Cream Versus Mary & May Tranexamic Acid + Glutathione Eye Cream
This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Dipeptide Diaminobutyroyl Benzylamide Diacetate to soften the look of wrinkles.
This brightening eye moisturizer is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningHydrolyzed Collagen
EmollientGlycerin
HumectantC12-15 Alkyl Benzoate
AntimicrobialCetearyl Alcohol
EmollientCetyl Ethylhexanoate
EmollientCyclohexasiloxane
Emollient1,2-Hexanediol
Skin ConditioningPrunus Amygdalus Dulcis Oil
Skin ConditioningButoxyethanol
MaskingArginine
MaskingCarbomer
Emulsion StabilisingDimethicone
EmollientGlyceryl Stearate
EmollientOlea Europaea Fruit Oil
MaskingPolysorbate 60
EmulsifyingBeeswax
Emulsion StabilisingPEG-100 Stearate
SurfactantSodium Polyacrylate
AbsorbentPalmitic Acid
EmollientStearic Acid
CleansingParfum
MaskingYeast
Skin ConditioningHydrogenated Lecithin
EmulsifyingEthylhexylglycerin
Skin ConditioningAdenosine
Skin ConditioningAnthemis Nobilis Flower Extract
MaskingDisodium EDTA
ChelatingPolyglyceryl-10 Laurate
Skin ConditioningMalt Extract
Skin ProtectingPentylene Glycol
Skin ConditioningPanthenol
Skin ConditioningHexyldecanol
EmollientCeramide NP
Skin ConditioningHydrolyzed Elastin
EmollientPalmitoyl Tripeptide-5
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningCentella Asiatica Extract
CleansingLavandula Angustifolia Extract
Skin ConditioningWater, Hydrolyzed Collagen, Glycerin, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Cetyl Ethylhexanoate, Cyclohexasiloxane, 1,2-Hexanediol, Prunus Amygdalus Dulcis Oil, Butoxyethanol, Arginine, Carbomer, Dimethicone, Glyceryl Stearate, Olea Europaea Fruit Oil, Polysorbate 60, Beeswax, PEG-100 Stearate, Sodium Polyacrylate, Palmitic Acid, Stearic Acid, Parfum, Yeast, Hydrogenated Lecithin, Ethylhexylglycerin, Adenosine, Anthemis Nobilis Flower Extract, Disodium EDTA, Polyglyceryl-10 Laurate, Malt Extract, Pentylene Glycol, Panthenol, Hexyldecanol, Ceramide NP, Hydrolyzed Elastin, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Centella Asiatica Extract, Lavandula Angustifolia Extract
Water
Skin ConditioningEthylhexyl Palmitate
EmollientGlycereth-26
HumectantGlycerin
HumectantCetearyl Alcohol
EmollientNiacinamide
SmoothingHydrogenated Poly(C6-14 Olefin)
EmollientBeeswax
Emulsion StabilisingCaprylic/Capric Triglyceride
MaskingPolyglyceryl-2 Stearate
EmulsifyingDipropylene Glycol
HumectantIsododecane
EmollientGlyceryl Stearate
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingStearyl Alcohol
EmollientGlycol Stearate Se
EmulsifyingSodium Polyacrylate
AbsorbentHydroxyacetophenone
AntioxidantStearic Acid
CleansingDimethiconol
EmollientDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningHydrogenated Polydecene
EmollientHydrogenated Lecithin
EmulsifyingTranexamic Acid
AstringentBetaine
HumectantGlutathione
Panthenol
Skin ConditioningParfum
MaskingHippophae Rhamnoides Fruit Oil
Skin ProtectingButylene Glycol
HumectantAdenosine
Skin ConditioningSorbitan Isostearate
EmulsifyingCaprylyl Glycol
EmollientTrideceth-6
Emulsifying1,2-Hexanediol
Skin ConditioningDisodium EDTA
ChelatingSodium Hyaluronate
HumectantAscorbic Acid
AntioxidantWater, Ethylhexyl Palmitate, Glycereth-26, Glycerin, Cetearyl Alcohol, Niacinamide, Hydrogenated Poly(C6-14 Olefin), Beeswax, Caprylic/Capric Triglyceride, Polyglyceryl-2 Stearate, Dipropylene Glycol, Isododecane, Glyceryl Stearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Stearyl Alcohol, Glycol Stearate Se, Sodium Polyacrylate, Hydroxyacetophenone, Stearic Acid, Dimethiconol, Dimethicone/Vinyl Dimethicone Crosspolymer, Hydrogenated Polydecene, Hydrogenated Lecithin, Tranexamic Acid, Betaine, Glutathione, Panthenol, Parfum, Hippophae Rhamnoides Fruit Oil, Butylene Glycol, Adenosine, Sorbitan Isostearate, Caprylyl Glycol, Trideceth-6, 1,2-Hexanediol, Disodium EDTA, Sodium Hyaluronate, Ascorbic Acid
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineBeeswax is natural wax produced by honey bees to build their honeycomb.
Because it forms a protective layer on your skin, it can help lock in moisture and reduce water loss. It is also widely used as a thickener and emulsifier in lip balms and lotions. Research suggests beeswax containing moisturizers can support skin barrier integrity.
In comedogenic testing, Beeswax scored a 0-2, which is on the low end. Whether or not a product clogs your pores really comes down to the formula as a whole (not any single ingredient on its own) and your skin.
Cera Alba is the white, bleached form of this ingredient.
Just so you know, beeswax is not vegan since it is animal-derived. It cannot be removed with water, but can be taken off with an oil cleanser.
People with a known Propolis allergy also report to have reactions from beeswax.
Beeswax's wax esters are derived primarily from palmitic and oleic acid (C16 and C18:1). Both of these fall within the C11-C24 feeding window.
The Malassezia yeast can potentially cleave these esters and release usable fatty acids, so this ingredient may not be fungal acne safe. However, not everyone will react to this ingredient.
Learn more about BeeswaxCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumSodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.
This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.
Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
This ingredient does have a comedogenic rating of 2-3, but this doesn't mean a formula with this ingredient will clog pores.
Human testing has proved that any finished product with this ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin.
Learn more about Stearic AcidWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water