Drunk Elephant Protini Polypeptide Cream - US Versus Stratia Interface Cream
Updated on March 19, 2025
Overview
What they are
These products are both cruelty-free general moisturizers. They have a total of 18 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens or sulfates
What's Inside
They both contain oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Stratia Interface Cream 35 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Stratia Interface Cream 35 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDicaprylyl Carbonate
EmollientGlycerin
Humectant
Cetearyl Alcohol
Emollient
Cetearyl Olivate
Sorbitan Olivate
Emulsifying
Sclerocarya Birrea Seed Oil
Humectant
Bacillus/Folic Acid Ferment Filtrate Extract
Antioxidant
Nymphaea Alba Root Extract
Skin ConditioningSh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Alanine
MaskingArginine
Masking
Glycine
Buffering
Histidine
Humectant
Isoleucine
Skin ConditioningPhenylalanine
Masking
Proline
Skin ConditioningSerine
Masking
Threonine
Valine
MaskingAcetyl Glutamine
Skin ConditioningCoconut Alkanes
Emollient
Coco-Caprylate/Caprate
Emollient
Sodium Hyaluronate
Humectant
Aspartic Acid
Masking
Linoleic Acid
Cleansing
Linolenic Acid
Cleansing
Lecithin
Emollient
Butylene Glycol
Humectant
Polyvinyl Alcohol
Sodium Lactate
BufferingSodium PCA
Humectant
PCA
Humectant
Sorbitan Isostearate
Emulsifying
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Polysorbate 60
Emulsifying
Lactic Acid/Glycolic Acid Copolymer
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingXanthan Gum
EmulsifyingIsomalt
Humectant1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
EmollientChlorphenesin
Antimicrobial
Phenoxyethanol
Preservative
Tocopherol
Antioxidant
Sodium Benzoate
Masking
Phenylpropanol
Masking
Glyceryl Caprylate
EmollientSymphytum Officinale Callus Culture Extract
Skin ConditioningWater, Dicaprylyl Carbonate, Glycerin, Cetearyl Alcohol, Cetearyl Olivate, Sorbitan Olivate, Sclerocarya Birrea Seed Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Nymphaea Alba Root Extract, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Alanine, Arginine, Glycine, Histidine, Isoleucine, Phenylalanine, Proline, Serine, Threonine, Valine, Acetyl Glutamine, Coconut Alkanes, Coco-Caprylate/Caprate, Sodium Hyaluronate, Aspartic Acid, Linoleic Acid, Linolenic Acid, Lecithin, Butylene Glycol, Polyvinyl Alcohol, Sodium Lactate, Sodium PCA, PCA, Sorbitan Isostearate, Carbomer, Polysorbate 20, Polysorbate 60, Lactic Acid/Glycolic Acid Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Isomalt, 1,2-Hexanediol, Caprylyl Glycol, Chlorphenesin, Phenoxyethanol, Tocopherol, Sodium Benzoate, Phenylpropanol, Glyceryl Caprylate, Symphytum Officinale Callus Culture Extract
Water
Skin ConditioningGlycerin
Humectant
Squalane
Emollient
Hydrogenated Polydecene
EmollientPanthenol
Skin Conditioning
Ethoxydiglycol
HumectantDimethicone
Emollient
Rosa Canina Fruit Oil
Emollient
Cetearyl Alcohol
Emollient
Acetyl Glutamine
Skin ConditioningSh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Polypeptide-11
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Glycyrrhiza Glabra Root Extract
Bleaching
Allantoin
Skin Conditioning
Caprylyl Glycol
EmollientButylene Glycol
Humectant
Sodium Hyaluronate
Humectant
Glycolic Acid
Buffering
Lactic Acid/Glycolic Acid Copolymer
Skin ConditioningDisodium EDTA
Polyacrylamide
Potassium Sorbate
Preservative
Sodium Benzoate
Masking
C13-14 Isoparaffin
Emollient
Polyvinyl Alcohol
Methylparaben
Preservative
Propylparaben
Preservative
Laureth-7
EmulsifyingDiazolidinyl Urea
Preservative
Xanthan Gum
EmulsifyingWater, Glycerin, Squalane, Hydrogenated Polydecene, Panthenol, Ethoxydiglycol, Dimethicone, Rosa Canina Fruit Oil, Cetearyl Alcohol, Acetyl Glutamine, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Glycyrrhiza Glabra Root Extract, Allantoin, Caprylyl Glycol, Butylene Glycol, Sodium Hyaluronate, Glycolic Acid, Lactic Acid/Glycolic Acid Copolymer, Disodium EDTA, Polyacrylamide, Potassium Sorbate, Sodium Benzoate, C13-14 Isoparaffin, Polyvinyl Alcohol, Methylparaben, Propylparaben, Laureth-7, Diazolidinyl Urea, Xanthan Gum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl Alcoholsh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
This peptide is the copper salt and formed by reacting palmitic acid and heptapeptide-14.
This uses a high-tech delivery system called The Cosmetic Drone, where the peptide is enclosed in a shell made from Lactic Acid/Glycolic Acid Copolymer and Polyvinyl Alcohol. Another peptide on the outside guides the capsule to fibroblast cells, the collagen-producing cells in the skin.
Once it reaches the fibroblasts, Copper Palmitoyl Heptapeptide-14 boosts the production of collagen and elastin.
This advanced system works at an incredibly low concentration of just 0.001%.
Learn more about Copper Palmitoyl Heptapeptide-14Heptapeptide-15 Palmitate isn't fungal acne safe and is a peptide.
We don't have a description for Acetyl Glutamine yet.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolWe don't have a description for Polyvinyl Alcohol yet.
This ingredient is a combination of two AHAs, lactic acid and glycolic acid. It has exfoliating properties
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Drunk Elephant Protini Polypeptide Cream 58 ingredients
Stratia Interface Cream 35 ingredients
Reviews
Here's what our community thinks
Drunk Elephant Protini Polypeptide Cream 58 ingredients
for the price point of this moisturizer i feel like i expected a lot more?
i mostly used this moisturizer at night paired with my tretinoin and i found that the 2 worked well with each other. it’s a really nice almost gel-like cream texture with a light fragrance. i found it a little hard to blend while my face was still damp which is when i usually apply moisturizer. i don’t feel like it did Show more
My HG facial moisturizer. It makes my face feel so soft and velvety. It dries quickly, is gentle even when my face is on fire and it has a slight "chemical" smell that I tend to like. I love the pump as well. I use this when I need a good hit of luxury.
Stratia Interface Cream 35 ingredients
I’ve only purchased this product once, and while I like it, it didn’t make the cut because I’ve since made changes to my regular routine and I already had something similar. That said, I enjoyed its lightweight moisturizing formula—it layered perfectly under makeup and was great when applied over Retinal, which my skin loved.
The downside for me is the packaging. The pump container makes it Show more
