YSE Beauty Last Call Retinol Serum
A serum with 42 ingredients, including AHA, retinoid, and niacinamide.
Overview
What it is
Serum with 42 ingredients that contains AHA, hyaluronic acid, niacinamide, retinoid and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any common allergens, parabens or sulfates
Fun facts
YSE Beauty is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningTetradecane
PerfumingPropanediol
SolventCaprylic/Capric Triglyceride
MaskingPentylene Glycol
Skin ConditioningDimethicone
EmollientCetearyl Alcohol
EmollientNiacinamide
SmoothingRetinol
Skin ConditioningSodium Hyaluronate
HumectantGlycerin
HumectantHelianthus Annuus Seed Oil
EmollientAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingTridecane
PerfumingHumulus Lupulus Extract
AntimicrobialSodium Carboxymethyl Beta-Glucan
CleansingCitric Acid
BufferingGlyceryl Stearate
EmollientDimethicone Crosspolymer
Emulsion StabilisingJojoba Esters
EmollientEthyl Ferulate
AntioxidantLinoleic Acid
CleansingPhospholipids
Skin ConditioningPhytosterols
Skin ConditioningGlycolic Acid
BufferingSodium Stearoyl Glutamate
CleansingAlcohol Denat.
AntimicrobialCaprylyl Glycol
EmollientAcacia Senegal Gum
Masking1,2-Hexanediol
Skin ConditioningCopernicia Cerifera Wax
Polyglycerin-3
HumectantTocopherol
AntioxidantTetrasodium Glutamate Diacetate
Helianthus Annuus Seed Wax
Skin ConditioningPhenoxyethanol
PreservativeSodium Hydroxide
BufferingXanthan Gum
EmulsifyingEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingPolysorbate 20
EmulsifyingSodium Cocoamphoacetate
CleansingWater, Tetradecane, Propanediol, Caprylic/Capric Triglyceride, Pentylene Glycol, Dimethicone, Cetearyl Alcohol, Niacinamide, Retinol, Sodium Hyaluronate, Glycerin, Helianthus Annuus Seed Oil, Ammonium Polyacryloyldimethyl Taurate, Tridecane, Humulus Lupulus Extract, Sodium Carboxymethyl Beta-Glucan, Citric Acid, Glyceryl Stearate, Dimethicone Crosspolymer, Jojoba Esters, Ethyl Ferulate, Linoleic Acid, Phospholipids, Phytosterols, Glycolic Acid, Sodium Stearoyl Glutamate, Alcohol Denat., Caprylyl Glycol, Acacia Senegal Gum, 1,2-Hexanediol, Copernicia Cerifera Wax, Polyglycerin-3, Tocopherol, Tetrasodium Glutamate Diacetate, Helianthus Annuus Seed Wax, Phenoxyethanol, Sodium Hydroxide, Xanthan Gum, Ethylhexylglycerin, Hexylene Glycol, Polysorbate 20, Sodium Cocoamphoacetate
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterTetradecane is a fragrance.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglyceridePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl AlcoholNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHelianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.
Sunflower seed oil contains many fatty acids. The fatty acids found in sunflower seeds include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.
These fatty acids help the skin create ceramides. Ceramides play a role in repairing the skin barrier.
Helianthus Annuus Seed Oil helps moisturize the skin. This in turn helps the skin look more rejuvenated and smoother.
Sunflowers are rich in vitamin E.
Historians believe Indigenous cultures of North America domesticated sunflowers before corn. Thus they relied on sunflower oil for a variety of uses. One such use is moisturizing skin and hair.
Sunflower seed oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Helianthus Annuus Seed OilAmmonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product. This ingredient is stable over a wide pH range.
Due to its ability to absorb water, it can help thicken the texture of a product. As an emulsion stabilizer, this ingredient is stabilizes other ingredients to create a consistent texture.
According to a manufacturer, it helps create a "smooth, light and fresh" texture.
Learn more about Ammonium Polyacryloyldimethyl TaurateTridecane is a lightweight emollient and fragrancing ingredient. It is a paraffin and often called a silicone alternative.
According to official INCI guidelines, this ingredient is used to give a light odor to raw materials. It is often used as a starter ingredient to create parfum.
This ingredient can be derived from palm oil, or coconut oil. It is also naturally found in certain species of organisms.
According to the NOAA, this ingredient can cause skin sensitivity with prolonged use. However, this warning is taken from the Coast Guard and no studies have been done on this in relation to cosmetics.
Tridecane is not water soluble.
Learn more about TridecaneWe don't have a description for Humulus Lupulus Extract yet.
We don't have a description for Sodium Carboxymethyl Beta-Glucan yet.
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateDimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.
This ingredient has high oxidative stability, meaning it doesn't break down when exposed to oxygen.
Its similarity to our skin's natural oils makes it a great emollient. Emollients help soften and soothe our skin by creating a barrier on top. This barrier helps trap moisture in, keeping skin hydrated.
It is created using either the hydrogenation or transesterification processes on jojoba oil.
Learn more about Jojoba EstersEthyl ferulate is an antioxidant derived from ferulic acid and ethyl alcohol. You'll most likely see this ingredient in sunscreens.
One study from 2014 found a concentration of 10% showed a similar SPF to Benzimidazole. Though this is considered a chemical UV filter, this ingredient is not listed as so. This is due to regulatory loopholes. You'll likely find this ingredient in "100% mineral" sunscreens.
This ingredient is typically found in concentrations between 0.5-1%. It is usually created synthetically or from rice bran oil.
Learn more about Ethyl FerulateLinoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties. Our top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.
Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing. Needless to say, linoleic acid is crucial for having a strong skin barrier.
One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.
Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.
Acne-prone skin tends to have linoleic acid and high levels of oleic acid.
Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.
This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.
Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.
Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.
Learn more about Linoleic AcidPhospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.
Due to their hygroscopic nature, they act as both humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in.
The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin.
Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.
This ingredient is non-occlusive.
Some types of phospholipids:
Learn more about PhospholipidsPhytosterols come from plants, nuts, and whole grains. These compounds have skin soothing and moisturizing properties.
Fun fact: They are similar to cholesterol and can help lower cholesterol levels.
Glycolic Acid is arguably the most famous AHA with a ton of research to back up its benefits.
Its main role is to remove the top layer of dead skin cells, allowing newer skin cells to emerge.
Specifically, AHAs work by breaking down the structural "glue" holding the old skin cells in place. Getting rid of the old skin cells allows skin to regenerate newer skin cells in its place. A build up of dead skin cells can lead to tired and dull looking skin.
Due to this, glycolic acid helps with:
Fun fact: Glycolic acid increases skin hydration by playing a role in creating molecules that create hyaluronic acid naturally.
When starting glycolic Acid, it is normal to feel slight stinging.
The pH value and concentration of glycolic acid play a role in the effectiveness of the product. Concentrations between 5-20% glycolic acid have been shown to be effective in clinical studies.
Recent studies have shown Glycolic Acid may protect the skin against UV damage. However, you should always wear SPF, especially when using exfoliants.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidSodium Stearoyl Glutamate is an emulsifier and helps condition the skin. It is amino acid-based.
In higher amounts, it may act as a cleansing agent.
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Other types of astringent alcohols include:
Learn more about Alcohol Denat.Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolAcacia Senegal Gum has skin soothing, thickening, and formulation stabilizing properties. It comes from the Acacia tree that is native to sub-Saharan Africa.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Copernicia Cerifera Wax comes from a palm tree native to Brazil; another name for this ingredient is Carnauba Wax.
This ingredient is used to thicken texture and also leaves behind a film when applied.
Fun fact: This wax has the highest melting point of all natural waxes and low solubility.
Learn more about Copernicia Cerifera WaxPolyglycerin-3 is a 3-unit glycerin polymer.
Like glycerin, this ingredient is a humectant. Humectants help hydrate your skin by drawing water to it.
Having moisturized skin helps improve the skin barrier. Your skin barrier helps protect against irritants and bacteria.
Learn more about Polyglycerin-3Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolTetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Helianthus Annuus Seed Wax is created from the common sunflower.
Sunflower seed wax is made up of long chain non-glyceride esters, a small amount of fatty alcohols, and fatty acids.
This ingredient is often used to enhance the texture of products. The fatty acid properties also help hydrate the skin.
Learn more about Helianthus Annuus Seed WaxPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.
As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.
Hexylene Glycol has a small molecular weight.
Learn more about Hexylene GlycolPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20We don't have a description for Sodium Cocoamphoacetate yet.
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Where it's from
YSE Beauty is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published September 15, 2025