Versus

Sunday Riley A+ High-Dose Retinol Serum Versus Biossance Squalane + Phyto-Retinol Serum

Serum
Serum
American Brand
American Brand

Updated on June 03, 2025

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 6 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any parabens or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
A+ High-Dose Retinol Serum

Water

Skin Conditioning

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Dimethyl Isosorbide

Solvent

Triheptanoin

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Pentylene Glycol

Skin Conditioning

Hexyldecanol

Emollient

Disiloxane

Skin Conditioning
Silicon Icon

Cetyl PEG/PPG-10/1 Dimethicone

Emulsifying
Silicon Icon

Diheptyl Succinate

Emollient

Propylene Carbonate

Solvent

Hydroxypinacolone Retinoate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

PPG-24-Glycereth-24

Emulsifying

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Ubiquinone

Antioxidant
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

Honey Extract

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Algae Extract

Emollient
May worsen Oily Skin Icon

Zingiber Officinale Extract

Skin Conditioning

Opuntia Ficus-Indica Fruit Extract

Skin Conditioning

Bisabolol

Masking
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Phospholipids

Skin Conditioning
Helps hydrate Dry Skin Icon

Saccharomyces Cerevisiae Extract

Skin Conditioning

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Sodium Acrylates Copolymer

Hydrogenated Polyisobutene

Emollient
1 / 2

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

4-T-Butylcyclohexanol

Masking
Fragrance IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Polyglyceryl-10 Stearate

Skin Conditioning
Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Cetylhydroxyproline Palmitamide

Skin Conditioning

Polysilicone-11

Benzoic Acid

Masking
Preservative IconMay worsen Eczema Icon

Dehydroacetic Acid

Preservative
Preservative Icon

Sodium Phytate

Glyceryl Polyacrylate

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Hydroxyphenyl Propamidobenzoic Acid

Skin Conditioning

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Brassica Campestris Sterols

Emollient
Not safe for Fungal Acne Icon

Pvp

Emulsion Stabilising
0 / 0

Capryloyl Glycerin/Sebacic Acid Copolymer

Skin Conditioning

Sodium Benzoate

Masking
Preservative Icon

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Potassium Phosphate

Buffering

Decyl Glucoside

Cleansing

Phenoxyethanol

Preservative
Preservative Icon

Hexylene Glycol

Emulsifying
0-2 / 0-1

Potassium Sorbate

Preservative
Preservative Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsifying, Skin Conditioning, Solvent

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.

As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.

Hexylene Glycol has a small molecular weight.

Learn more about Hexylene Glycol
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Learn more about Lecithin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

We don't have a description for Sodium Acrylates Copolymer yet.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

170 Routines
5% use in am
95% use in pm
70% use every day
When to use See routines that use it ->
34 Routines
21% use in am
79% use in pm
79% use every day
When to use See routines that use it ->

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