Skinfix Barrier+ Triple Lipid + Collagen + Niacinamide Activating Serum Versus SkinCeuticals P-Tiox Wrinkle Modulating Peptide Serum
This barrier-repair serum is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging serum is formulated around Dipeptide Diaminobutyroyl Benzylamide Diacetate and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylyl Caprylate/Caprate
EmollientPropanediol
SolventJojoba Oil/Macadamia Seed Oil Esters
Skin ConditioningNiacinamide
SmoothingGlycerin
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Squalene
EmollientMacadamia Integrifolia Seed Oil
Skin ConditioningAmylopectin
Lecithin
EmollientPhytosteryl Macadamiate
Skin ConditioningCollagen Amino Acids
MoisturisingLithothamnion Calcareum Extract
Skin ConditioningSodium Hyaluronate
HumectantOligopeptide-3
Skin ConditioningOligopeptide-2
Skin ConditioningOligopeptide-1
Skin ConditioningHexapeptide-11
Skin ConditioningFolic Acid
Skin ConditioningBacillus/Soybean Ferment Extract
Skin ConditioningLactic Acid
BufferingPhospholipids
Skin ConditioningCeramide NP
Skin ConditioningPhytosterols
Skin ConditioningPhytosphingosine
Skin ConditioningCeramide AP
Skin ConditioningCholesterol
EmollientMyrica Cerifera Fruit Extract
HumectantAkebia Quinata Stem Extract
Skin ConditioningPrunus Lannesiana Flower Extract
Skin ConditioningSaccharomyces Lysate
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningTripeptide-1
Skin ConditioningCeramide EOP
Skin ConditioningPolyglutamic Acid
Skin ConditioningTocopheryl Acetate
AntioxidantTocopherol
AntioxidantButylene Glycol
HumectantCaprylyl Glycol
EmollientSodium Lauroyl Lactylate
EmulsifyingEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingPentylene Glycol
Skin ConditioningAcetyl Glutamine
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Leuconostoc/Radish Root Ferment Filtrate
AntimicrobialSodium Benzoate
MaskingHydroxyacetophenone
AntioxidantXanthan Gum
EmulsifyingPotassium Sorbate
PreservativeCarbomer
Emulsion Stabilising1,2-Hexanediol
Skin ConditioningDextran
Phenoxyethanol
PreservativeWater, Caprylyl Caprylate/Caprate, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Niacinamide, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Macadamia Integrifolia Seed Oil, Amylopectin, Lecithin, Phytosteryl Macadamiate, Collagen Amino Acids, Lithothamnion Calcareum Extract, Sodium Hyaluronate, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Folic Acid, Bacillus/Soybean Ferment Extract, Lactic Acid, Phospholipids, Ceramide NP, Phytosterols, Phytosphingosine, Ceramide AP, Cholesterol, Myrica Cerifera Fruit Extract, Akebia Quinata Stem Extract, Prunus Lannesiana Flower Extract, Saccharomyces Lysate, Lactobacillus Ferment Lysate, Tripeptide-1, Ceramide EOP, Polyglutamic Acid, Tocopheryl Acetate, Tocopherol, Butylene Glycol, Caprylyl Glycol, Sodium Lauroyl Lactylate, Ethylhexylglycerin, Hexylene Glycol, Pentylene Glycol, Acetyl Glutamine, Trisodium Ethylenediamine Disuccinate, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Hydroxyacetophenone, Xanthan Gum, Potassium Sorbate, Carbomer, 1,2-Hexanediol, Dextran, Phenoxyethanol
Water
Skin ConditioningNiacinamide
SmoothingGluconolactone
Skin ConditioningButylene Glycol
HumectantPEG/PPG/Polybutylene Glycol-8/5/3 Glycerin
HumectantAlcohol Denat.
AntimicrobialPentylene Glycol
Skin ConditioningMethyl Gluceth-20
HumectantGlycerin
HumectantPotassium Hydroxide
BufferingHydroxyethylcellulose
Emulsion StabilisingSalicylic Acid
MaskingChlorphenesin
AntimicrobialPhytic Acid
Adenosine
Skin ConditioningSodium Benzoate
MaskingLaminaria Digitata Extract
Skin ProtectingDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningAcetyl Hexapeptide-8
HumectantWater, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water