Paula's Choice Resist Super Antioxidant Serum Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment
Updated on May 28, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 5 ingredients in common
Cool Features
They both contain ceramides, peptides, Vitamin C and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment 54 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment 54 ingredients
Key Ingredients
Benefits
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Cyclopentasiloxane
Emollient
Dimethicone
Emollient
Tetrahexyldecyl Ascorbate
Antioxidant
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide NP
Skin Conditioning
Tocotrienols
Skin ConditioningTocopherol
Antioxidant
Ubiquinone
Antioxidant
Thioctic Acid
Antioxidant
Tocopheryl Acetate
Antioxidant
Magnesium Ascorbyl Phosphate
Antioxidant
Ferulic Acid
Antimicrobial
Beta-Glucan
Skin Conditioning
Superoxide Dismutase
Antioxidant
Epigallocatechin Gallate
Antioxidant
Ergothioneine
Antioxidant
Glutathione
Xanthophylls
Skin ConditioningGlycine Soja Seed Extract
Skin Conditioning
Glycerin
Humectant
Arctostaphylos Uva Ursi Leaf Extract
Skin Conditioning
Lupinus Albus Seed Extract
Skin ConditioningCurcuma Longa Root
Skin ConditioningElaeis Guineensis Oil
Emollient
Phenoxyethanol
Preservative
Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol
Water
Skin ConditioningDimethicone
Emollient
Pentaerythrityl Tetraisostearate
Emollient
Isononyl Isononanoate
EmollientButylene Glycol
Humectant
Bakuchiol
Antimicrobial
Arachidyl Alcohol
EmollientGlyceryl Polymethacrylate
Dimethicone Crosspolymer
Emulsion StabilisingBehenyl Alcohol
Emollient
Glycerin
Humectant
PEG-75 Shea Butter Glycerides
Emulsifying
Glyceryl Stearate
Emollient
C12-15 Alkyl Benzoate
AntimicrobialPolysorbate 20
Emulsifying
Tetrahexyldecyl Ascorbate
Antioxidant
Retinol
Skin Conditioning
Ceramide Ng
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Sodium Hyaluronate
Humectant
Dipotassium Glycyrrhizate
Humectant
Glycyrrhiza Glabra Root Extract
Bleaching
Avena Sativa Kernel Extract
Abrasive
Arctium Lappa Root Extract
Skin Conditioning
Salix Alba Bark Extract
Astringent
Glycine Soja Sterols
Emollient
Lecithin
Emollient
Allantoin
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Hydrolyzed Soy Protein
Humectant
Palmitoyl Tripeptide-1
Skin Conditioning
Sodium Hydroxide
BufferingTribehenin
Emollient
Caprylyl Glycol
EmollientDipeptide-2
Skin Conditioning
Polygonum Cuspidatum Root Extract
Antioxidant
PEG-10 Phytosterol
EmulsifyingPEG-8
HumectantMagnesium Aluminum Silicate
AbsorbentArachidyl Glucoside
EmulsifyingChrysin
Skin ConditioningPentylene Glycol
Skin ConditioningSodium Acrylates Copolymer
Steareth-20
CleansingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
Emollient
Coco-Glucoside
CleansingHesperidin Methyl Chalcone
Antioxidant
N-Hydroxysuccinimide
Skin ConditioningDisodium EDTA
Phenoxyethanol
Preservative
Benzoic Acid
Masking
Ethylhexylglycerin
Skin ConditioningWater, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Paula's Choice Resist Super Antioxidant Serum 25 ingredients
Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment 54 ingredients
Reviews
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