NeoStrata Defend Sheer Hydration Sunscreen Broad Spectrum SPF 40 Versus La Roche-Posay SPF 50 Anthelios Age Correct
This chemical sunscreen covers most of the UV range, lighter on the deep UVA that drives aging.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Butyl Methoxydibenzoylmethane 3%
UV AbsorberEthylhexyl Methoxycinnamate 7.5%
UV AbsorberEthylhexyl Salicylate 5%
UV AbsorberWater
Skin ConditioningAcetyl Glucosamine
Skin ConditioningButyloctyl Salicylate
Skin ConditioningCyclopentasiloxane
EmollientDimethicone
EmollientC12-15 Alkyl Benzoate
AntimicrobialGlycerin
HumectantButylene Glycol
HumectantGlyceryl Stearate
EmollientOctyldodecyl Neopentanoate
EmollientCetyl Alcohol
EmollientPEG-100 Stearate
SurfactantCetearyl Alcohol
EmollientVitis Vinifera Seed Extract
AntimicrobialMelia Azadirachta Leaf Extract
Skin ConditioningLecithin
EmollientArctium Lappa Root Extract
Skin ConditioningTocopheryl Acetate
AntioxidantDimethicone Crosspolymer
Emulsion StabilisingPropylene Glycol
HumectantPEG-75 Stearate
SurfactantSteareth-20
CleansingXanthan Gum
EmulsifyingCeteth-20
CleansingAmmonium Hydroxide
BufferingCarbomer
Emulsion StabilisingDisodium EDTA
Caprylyl Glycol
EmollientPhenoxyethanol
PreservativeChlorphenesin
AntimicrobialSodium Bisulfite
AntioxidantButyl Methoxydibenzoylmethane 3%, Ethylhexyl Methoxycinnamate 7.5%, Ethylhexyl Salicylate 5%, Water, Acetyl Glucosamine, Butyloctyl Salicylate, Cyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate, Glycerin, Butylene Glycol, Glyceryl Stearate, Octyldodecyl Neopentanoate, Cetyl Alcohol, PEG-100 Stearate, Cetearyl Alcohol, Vitis Vinifera Seed Extract, Melia Azadirachta Leaf Extract, Lecithin, Arctium Lappa Root Extract, Tocopheryl Acetate, Dimethicone Crosspolymer, Propylene Glycol, PEG-75 Stearate, Steareth-20, Xanthan Gum, Ceteth-20, Ammonium Hydroxide, Carbomer, Disodium EDTA, Caprylyl Glycol, Phenoxyethanol, Chlorphenesin, Sodium Bisulfite
Water
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialGlycerin
HumectantOctocrylene
UV AbsorberNiacinamide
SmoothingButyl Methoxydibenzoylmethane
UV AbsorberDimethicone
EmollientEthylhexyl Triazone
UV AbsorberSilica
AbrasiveAluminum Starch Octenylsuccinate
AbsorbentVinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Terephthalylidene Dicamphor Sulfonic Acid
UV AbsorberPotassium Cetyl Phosphate
EmulsifyingDrometrizole Trisiloxane
UV AbsorberPEG-100 Stearate
SurfactantStearyl Alcohol
EmollientGlyceryl Stearate
EmollientAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingBenzyl Alcohol
PerfumingBenzyl Benzoate
AntimicrobialCapryloyl Salicylic Acid
ExfoliatingCaprylyl Glycol
EmollientHydrolyzed Hyaluronic Acid
HumectantPhenoxyethanol
PreservativePhenylethyl Resorcinol
AntioxidantPoloxamer 338
EmulsifyingTocopherol
AntioxidantTriethanolamine
BufferingTrisodium Ethylenediamine Disuccinate
Xanthan Gum
EmulsifyingParfum
MaskingWater, C12-15 Alkyl Benzoate, Glycerin, Octocrylene, Niacinamide, Butyl Methoxydibenzoylmethane, Dimethicone, Ethylhexyl Triazone, Silica, Aluminum Starch Octenylsuccinate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Terephthalylidene Dicamphor Sulfonic Acid, Potassium Cetyl Phosphate, Drometrizole Trisiloxane, PEG-100 Stearate, Stearyl Alcohol, Glyceryl Stearate, Ammonium Polyacryloyldimethyl Taurate, Benzyl Alcohol, Benzyl Benzoate, Capryloyl Salicylic Acid, Caprylyl Glycol, Hydrolyzed Hyaluronic Acid, Phenoxyethanol, Phenylethyl Resorcinol, Poloxamer 338, Tocopherol, Triethanolamine, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Parfum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Learn more about Butyl MethoxydibenzoylmethaneC12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long.
In cosmetics, it plays several roles:
The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility.
This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product.
It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own.
Overall, this ingredient is well tolerated.
This ingredient is fungal acne safe because it is an ester of benzoic acid.
Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food.
Benzoic acid is actually used as a preservative to stop yeast from growing.
The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well).
In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond.
So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth.
Learn more about C12-15 Alkyl BenzoateCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePeg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum