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This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.

One thing to note:
People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.

The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.

This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.

Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.

This ingredient can be found in makeup, sun care, and skincare.

The FDA requires batch-to-batch certification for this ingredient that is held to a pretty rigorous standard. That means the CI 17200 in your cosmetics has been tested and approved before it ever reaches you.

Contact allergy to cosmetic-grade dyes used at low concentrations are uncommon but has been documented before.

This ingredient also goes by the name D&C RED NO. 33.

CI 17200 has a comedogenic rating of 1 and an irritancy rating of 2 on a scale of 0-5. This is based on peer-reviewed research from the man who invented the comedogenic scale.

A 1 on the comedogenic scale is about as low as it gets without being a flat zero, and makes sense for CI 17200.

It's a water-soluble dye used at very small concentrations (typically 0.001-0.1%), so it dissolves into the water phase of a formula rather than sitting on your skin the way an oil or wax would.

The irritancy rating of 2 reflects that, like most synthetic dyes, there's a small possibility of mild irritation ( particularly for people with existing dye sensitivities).

For the vast majority of people, it's a non-issue at typical use levels.

It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.

Just so you know, the FDA ban on Red Dye No. 3 refers to CI 45430, not this ingredient. CI 45430 and CI 17200 are different chemical compounds with distinct safety and regulatory histories.

It's also worth noting that Red No. 3 (CI 45430) was already banned from cosmetics back in 1990, so the 2025 action just extended the ban to food and oral drugs. CI 17200 was never part of any of this.