Ipse Cosmetic Botonix Age-Defying Ampoule Versus SKIN1004 Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++
This anti-aging ampoule is formulated around Adenosine and Panax Ginseng Root Extract to soften the look of wrinkles and hydrate skin.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Cyclopentasiloxane
Emollient
Butylene Glycol
Humectant
Glycol
HumectantAlcohol Denat.
Antimicrobial
Betaine
Humectant
Cyclohexasiloxane
Emollient
Methyl Gluceth-20
Humectant
Dipropylene Glycol
HumectantGlycereth-26
Humectant
Silica
Abrasive
Octyldodeceth-16
EmulsifyingPEG-60 Hydrogenated Castor Oil
Emulsifying
Polyacrylate-13
Polyisobutene
Chlorphenesin
Antimicrobial
Dimethiconol
Emollient
Caprylyl Glycol
Emollient
Ethylhexylglycerin
Skin ConditioningArgania Spinosa Kernel Oil
Emollient
Carbomer
Emulsion StabilisingParfum
Masking
Arginine
Masking
Xanthan Gum
EmulsifyingHexanediol
Solvent1,2-Hexanediol
Skin Conditioning
Adenosine
Skin Conditioning
Polysorbate 20
Emulsifying
Sorbitan Isostearate
Emulsifying
Caramel
Cosmetic ColorantDisodium EDTA
ChelatingDipotassium Glycyrrhizate
Humectant
Sodium Hyaluronate
Humectant
Cyclotetrasiloxane
Emollient
Artemisia Vulgaris Extract
Skin Conditioning
Gold
Cosmetic ColorantCitrus Aurantifolia Fruit Extract
Skin ConditioningTripropylene Glycol
Antioxidant
Propylene Glycol
Humectant
Panax Ginseng Root Extract
Emollient
Acetyl Octapeptide-3
Humectant
Water, Glycerin, Cyclopentasiloxane, Butylene Glycol, Glycol, Alcohol Denat., Betaine, Cyclohexasiloxane, Methyl Gluceth-20, Dipropylene Glycol, Glycereth-26, Silica, Octyldodeceth-16, PEG-60 Hydrogenated Castor Oil, Polyacrylate-13, Polyisobutene, Chlorphenesin, Dimethiconol, Caprylyl Glycol, Ethylhexylglycerin, Argania Spinosa Kernel Oil, Carbomer, Parfum, Arginine, Xanthan Gum, Hexanediol, 1,2-Hexanediol, Adenosine, Polysorbate 20, Sorbitan Isostearate, Caramel, Disodium EDTA, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Cyclotetrasiloxane, Artemisia Vulgaris Extract, Gold, Citrus Aurantifolia Fruit Extract, Tripropylene Glycol, Propylene Glycol, Panax Ginseng Root Extract, Acetyl Octapeptide-3
Water
Skin ConditioningDibutyl Adipate
EmollientPropanediol
Solvent
Diethylamino Hydroxybenzoyl Hexyl Benzoate
UV Filter
Polymethylsilsesquioxane
Ethylhexyl Triazone
UV Absorber
Methylene Bis-Benzotriazolyl Tetramethylbutylphenol
UV Filter
Niacinamide
Smoothing
Coco-Caprylate/Caprate
Emollient
Caprylyl Methicone
Skin Conditioning
Diethylhexyl Butamido Triazone
UV Absorber
Glycerin
Humectant
1,2-Hexanediol
Skin Conditioning
Butylene Glycol
Humectant
Pentylene Glycol
Skin Conditioning
Behenyl Alcohol
Emollient
Poly C10-30 Alkyl Acrylate
Emulsion StabilisingPolyglyceryl-3 Methylglucose Distearate
Emulsifying
Decyl Glucoside
Cleansing
Tromethamine
BufferingCarbomer
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingSodium Stearoyl Glutamate
CleansingPolyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Xanthan Gum
EmulsifyingCentella Asiatica Extract
Cleansing
T-Butyl Alcohol
Perfuming
Sodium Hyaluronate
Humectant
Betula Platyphylla Japonica Bark Extract
Skin ConditioningTocopherol
Antioxidant
Hydrolyzed Hyaluronic Acid
Humectant
Camellia Sinensis Leaf Extract
Antimicrobial
Ginkgo Biloba Leaf Extract
Skin Conditioning
Brassica Oleracea Italica Sprout Extract
EmollientCamellia Japonica Leaf Extract
Skin ConditioningEruca Sativa Leaf Extract
Skin ConditioningMedicago Sativa Extract
TonicTriticum Vulgare Sprout Extract
Skin ConditioningInositol
Humectant
Hyaluronic Acid
Humectant
Water, Dibutyl Adipate, Propanediol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Polymethylsilsesquioxane, Ethylhexyl Triazone, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Niacinamide, Coco-Caprylate/Caprate, Caprylyl Methicone, Diethylhexyl Butamido Triazone, Glycerin, 1,2-Hexanediol, Butylene Glycol, Pentylene Glycol, Behenyl Alcohol, Poly C10-30 Alkyl Acrylate, Polyglyceryl-3 Methylglucose Distearate, Decyl Glucoside, Tromethamine, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Glutamate, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Xanthan Gum, Centella Asiatica Extract, T-Butyl Alcohol, Sodium Hyaluronate, Betula Platyphylla Japonica Bark Extract, Tocopherol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Extract, Ginkgo Biloba Leaf Extract, Brassica Oleracea Italica Sprout Extract, Camellia Japonica Leaf Extract, Eruca Sativa Leaf Extract, Medicago Sativa Extract, Triticum Vulgare Sprout Extract, Inositol, Hyaluronic Acid
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
