Versus

Dr. Althea 345 Relief Cream Versus Centellian24 Madeca Relief Lotion

General Moisturizer
General Moisturizer
Korean Brand South Korea
Korean Brand South Korea

Updated on December 10, 2024

Overview

What they are

These products are both vegan and reef safe general moisturizers. They have a total of 20 ingredients in common

Cool Features

They both contain ceramides, hyaluronic acid, niacinamide and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
345 Relief Cream

Water

Skin Conditioning

Propanediol

Solvent

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Cyclohexasiloxane

Emollient
Silicon Icon

1,2-Hexanediol

Skin Conditioning

Caprylic/Capric Triglyceride

Masking

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Polyglycerin-3

Humectant

Polyglyceryl-10 Stearate

Skin Conditioning
Not safe for Fungal Acne Icon

Hydrogenated Poly(C6-14 Olefin)

Emollient

Hydrogenated Polydecene

Emollient

Laminaria Japonica Extract

Skin Protecting

Eclipta Prostrata Leaf Extract

Skin Conditioning

Melia Azadirachta Flower Extract

Skin Conditioning

Houttuynia Cordata Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Oenothera Biennis Flower Extract

Astringent

Curcuma Longa Root Extract

Masking
Fragrance Icon

Ocimum Sanctum Leaf Extract

Skin Conditioning

Calendula Officinalis Flower Extract

Masking
Fragrance IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Agave Tequilana Leaf Extract

Astringent

Sargassum Fulvellum Extract

Skin Conditioning

Corallina Officinalis Extract

Skin Conditioning

Lavandula Angustifolia Flower Extract

Cleansing
May cause irritation IconEU Allergen Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Opuntia Ficus-Indica Stem Extract

Skin Conditioning

Gardenia Florida Fruit Extract

Skin Conditioning

Perilla Ocymoides Leaf Extract

Tonic

Hibiscus Sabdariffa Flower Extract

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Hydrogenated Lecithin

Emulsifying

Empetrum Nigrum Fruit Juice

Skin Conditioning

Dicaprylyl Carbonate

Emollient

C14-22 Alcohols

Emulsion Stabilising

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polymethylsilsesquioxane

Silicon Icon

Dipropylene Glycol

Masking

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

C12-20 Alkyl Glucoside

Emulsifying

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Ethylhexylglycerin

Skin Conditioning

Polyquaternium-51

Skin Conditioning

Tromethamine

Buffering

Fructooligosaccharides

Humectant

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Glycine Soja Sterols

Emollient
0 / 0 Not safe for Fungal Acne Icon

PEG-40 Castor Oil

Emulsifying
0 / 0 Oil IconNot safe for Fungal Acne Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Resveratrol

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Oligopeptide-1

Skin Conditioning
Peptide Icon

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon
Madeca Relief Lotion

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking

Ethylhexyl Stearate

Emollient
Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-3 Methylglucose Distearate

Emulsifying
Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

1,2-Hexanediol

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Sodium Stearoyl Glutamate

Cleansing

Dipropylene Glycol

Masking

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Emulsion Stabilising

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Citrus Aurantium Dulcis Peel Oil

Masking
Oil Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Salvia Officinalis Leaf Water

Masking

Propanediol

Solvent

Ethylhexylglycerin

Skin Conditioning

Eclipta Prostrata Leaf Extract

Skin Conditioning

Laminaria Japonica Extract

Skin Protecting

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Hydrogenated Lecithin

Emulsifying

Disodium EDTA

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Fructooligosaccharides

Humectant

Glyceryl Stearate Se

Emulsifying
3 / 2 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Acmella Oleracea Extract

Skin Protecting

Olea Europaea Fruit Oil

Masking
0-2 / 0 Fragrance IconOil IconNot safe for Fungal Acne Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Amaranthus Caudatus Seed Extract

Skin Conditioning

Ulmus Davidiana Root Extract

Skin Conditioning

Monarda Didyma Leaf Extract

Skin Conditioning

Ficus Carica Fruit Extract

Humectant

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiaticoside

Antioxidant
Antioxidant IconGood for Scar Healing Icon

Centella Asiatica Oil

Antimicrobial
Antioxidant IconOil Icon

Asiatic Acid

Skin Conditioning

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Chrysanthemum Parthenium Extract

Skin Conditioning

Soluble Proteoglycan

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Protecting

Laminaria Japonica Extract comes from a kelp more commonly known as 'sweet kelp'. It is commonly eaten in Japan, Korea, and China.

Sweet kelp is a humectant and helps hydrate your skin. Humectants draw moisture from the air to your skin.

Studies show Laminaria Japonica has antioxidant compounds. Antioxidants may help with anti-aging. Kelp also contains magnesium and zinc, making it great for calming inflammation and redness.

Learn more about Laminaria Japonica Extract
Skin Conditioning

Eclipta Prostrata Leaf Extract comes from the false daisy plant. False daisy contains antioxidant compounds such as flavonoids.

One study found false daisy to absorb UVA and UVB radiation. However, this should not replace your sunscreen.

False daisy is used in both traditional medicines and foods throughout Southeast Asia and India.

Learn more about Eclipta Prostrata Leaf Extract
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.

Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Skin Conditioning

Fructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.

This ingredient is a prebiotic and helps to hydrate the skin. Emerging studies are also showing fructooligosaccharides to have antioxidant properties.

As a humectant, Fructooligosaccharides helps draw moisture to the skin, helping to hydrate the skin.

Bananas, onions, garlic, asparagus, jícama, and leeks also contain fructooligosaccharides.

Learn more about Fructooligosaccharides
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.

As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.

Learn more about Beta-Glucan
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP

When to use

145 Routines
47% use in am
53% use in pm
95% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Dr. Althea 345 Relief Cream 56 ingredients

2.6 /5
from 5 ratings
Hydrating (3) Broke Me Out (3) Absorbs Well (2)
sila3's avatar

Sila

2 months ago
Review

I really like how well it moisturizers my skin, but it’s not even worth the hype at all its like the Tirtir Cushion overhyped. There are definitely better moisturizers out there it broke me out so i wouldn’t recommend😐.

#broke me out
#absorbs well
glittertimes's avatar

Ryan 🩷

2 months ago
Review

The hype on this moisturizer is real! This is amazing!!! It's hydrating, absorbs well, and the ingredients have already made my acne scars begin to fade. The 3-in-1 nature moisturizes, helps with blemishes, and soothes irritation and sensitivity.

PROS:
-Hydrates extremely well
-Reduces appearance of acne scars
-Moisturization LASTS
-Non irritating (great for sensitive skin!!)
-Non oily Show more

#expensive
#hydrating
#light
#absorbs well

Centellian24 Madeca Relief Lotion 48 ingredients

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