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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of Biossance Squalane + Retinol Night Serum versus Medik8 Crystal Retinal 3 .

Published on January 29, 2023

Overview

What they are

These products are both vegan and cruelty-free serums. They have a total of 10 ingredients in common

Cool Features

They both contain exfoliants, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum American Brand United States
Serum British Brand United Kingdom

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Price

Shop

Buy Squalane + Retinol Night Serum

Starts at $72.00
Shop

Buy Crystal Retinal 3

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Retinoid (2)
Vitamin E
Exfoliators

Benefits

Hydrating (3)
Good For Oily Skin (2)
Redness Reducing
Reduces Irritation
Skin Texture (2)
Reduces Large Pores (2)
Anti-Aging (3)
Dark Spots (2)
Scar Healing (4)
Acne Fighting (2)
Brightening (3)

Concerns

Drying (2)
May Worsen Oily Skin
Acne Trigger
Irritating (3)
Rosacea
Eczema

Notable Ingredients

Retinoid
Vitamin C (2)
Vitamin E
Exfoliators
Hyaluronic Acid

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing (2)
Skin Texture (3)
Reduces Large Pores
Anti-Aging (3)
Dark Spots (3)
Scar Healing (2)
Acne Fighting
Brightening (2)

Concerns

Drying
May Worsen Oily Skin
Acne Trigger (2)
Irritating
Rosacea
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Biossance Squalane + Retinol Night Serum contains this as ingredient number 1.

Medik8 Crystal Retinal 3 contains this as ingredient number 1.

2
What it does: Emollient, Skin Conditioning
Community Rating: Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane

Biossance Squalane + Retinol Night Serum contains this as ingredient number 2.

Medik8 Crystal Retinal 3 contains this as ingredient number 11.

3
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

Biossance Squalane + Retinol Night Serum contains this as ingredient number 3.

Medik8 Crystal Retinal 3 contains this as ingredient number 3.

4
What it does: Masking, Skin Conditioning
Community Rating: Mixed

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

Biossance Squalane + Retinol Night Serum contains this as ingredient number 4.

Medik8 Crystal Retinal 3 contains this as ingredient number 2.

5
What it does:
Community Rating: Disliked

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

As an emulsifier, it is used to prevent oils and waters from separating. It can also

Manufacturers use the name Olivem 1000. This ingredient has been found to preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria. This ingredient is grouped with Sorbitan Olivate under the name Olivem 1000.

Learn more about Cetearyl Olivate

Biossance Squalane + Retinol Night Serum contains this as ingredient number 5.

Medik8 Crystal Retinal 3 contains this as ingredient number 7.

6
What it does: Emulsifying
Community Rating: Very Disliked

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Sorbitan Olivate is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.

Manufacturers sell sorbitan olivate under the name OliveM 1000. OliveM 1000 a multifunctional ingredient. It is self-emulsifying. According to a manufacturer, OliveM 1000 does not disrupt natural skin biome.

Learn more about Sorbitan Olivate

Biossance Squalane + Retinol Night Serum contains this as ingredient number 6.

Medik8 Crystal Retinal 3 contains this as ingredient number 9.

7
What it does: Skin Conditioning
Community Rating: Liked

Retinal is a form of retinoid. Retinoids are a group of vitamin A compounds with anti-aging and acne fighting benefits.

Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.

Studies show retinal may work at a faster rate than retinol due to its structure. Retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.

Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient daily. It is best to avoid mixing other active ingredients if you have sensitive skin.

Learn more about Retinal

Biossance Squalane + Retinol Night Serum contains this as ingredient number 8.

Medik8 Crystal Retinal 3 contains this as ingredient number 13.

8
What it does: Emollient, Emulsifying, Emulsion Stabilising
Community Rating: Very Disliked

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol

Biossance Squalane + Retinol Night Serum contains this as ingredient number 15.

Medik8 Crystal Retinal 3 contains this as ingredient number 6.

9
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Biossance Squalane + Retinol Night Serum contains this as ingredient number 21.

Medik8 Crystal Retinal 3 contains this as ingredient number 30.

10
What it does: Skin Conditioning
Community Rating: Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Biossance Squalane + Retinol Night Serum contains this as ingredient number 22.

Medik8 Crystal Retinal 3 contains this as ingredient number 17.

Here's what our community thinks of the ingredients in these two products.

39% are loved or liked
22% have mixed ratings
22% are disliked or very disliked
17% have no rating yet
31% are loved or liked
15% have mixed ratings
36% are disliked or very disliked
18% have no rating yet

Usage

Here's some more info on how this product is used by our community.

When to use

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Reviews

Here's what our community thinks

Biossance Squalane + Retinol Night Serum 23 ingredients

5.0 /5
from 1 review

Medik8 Crystal Retinal 3 39 ingredients

5.0 /5
from 2 reviews

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Our Dupe Finder has found 6 potential alternatives that have similar ingredients to Medik8 Crystal Retinal 3.

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