Advanced Clinicals Retinol Serum Anti-Wrinkle Ingredients Explained
Published on June 11, 2022 Submitted by Ethereal_21
Overview
What it is
Serum with 36 ingredients that contains exfoliants, retinoid and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, oils, parabens, silicones or sulfates
Fun facts
Advanced Clinicals is from United States. This product is used in 18 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
Ingredient List (36)
Water, Isopropyl Myristate, Glycerin, Pyrus Malus Fruit Extract, Ethylhexyl Olivate, Cetearyl Alcohol, Aloe Barbadensis Leaf Juice, Squalane, Copernicia Cerifera Cera, Retinol, Propanediol, Sodium Cocoamphoacetate, Tocopheryl Acetate, BHA, Xanthan Gum, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Extract, Tocopherol, Cyamopsis Tetragonoloba Gum , Avena Sativa Bran Extract, Citrus Aurantium Dulcis Peel Extract, Camellia Sinensis Leaf Extract, Tetrasodium Glutamate Diacetate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Citric Acid, Parfum, Phenoxyethanol, Maltodextrin, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Butylphenyl Methylpropional, Linalool, Limonene, Citronellol
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Ingredient Info
Alcohol Free
This product is free of harsh alcohols 🎉
Silicon Free
This product is free of silicons 🎉
Contains Fragrance
Ingredients in this product that are forms of fragrance:
Sulfate Free
This product is free of sulfates 🎉
Paraben Free
This product is free of parabens 🎉
Oil Free
This product is free of oils 🎉
Not Malassezia Safe
Ingredients in this product that are not malassezia safe:
Reef Safe
This product is free of ingredients that damage reefs 🎉
Contains EU Allergens
Ingredients in this product that are EU allergens:
Non Vegan
This product is not vegan 😥
Cruelty Free
This product is cruelty-free 🎉
Ingredients Overview
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIsopropyl Myristate is an emollient, thickening agent, and texture enhancer. It is created from isopropyl alcohol and myristic acid.
It is used to help other ingredients be better absorbed. It is also an emollient and may help soften and hydrate the skin.
The comedogenic rating of this ingredient depends on the concentration. Lower amounts results in a lower rating.
Isopropyl Myristate may not be fungal acne safe. It can potentially worsen acne prone skin.
Learn more about Isopropyl MyristateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.
The sugar in Apples are humectants and help hydrate the skin. On top of that, apples also contain some acids, such as malic acid. These acids may have a mild exfoliating effect.
Last, the phytochemicals found in apples are strong antioxidants. These antioxidants help with anti-aging as they protect your skin cells against oxidative damage.
Learn more about Pyrus Malus Fruit ExtractCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl AlcoholAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneCopernicia Cerifera Cera isn't fungal acne safe.
Retinol is a form of Vitamin A and proven to help with anti-aging.
It promotes collagen production, increases new cell turnoever, and protects your skin as an antioxidant.
Retinol boosts collagen production and increases cell turnover. This makes retinol effective in removing wrinkles, fading dark spots, and reducing the appearance of pores.
Retinol is less effective when exposed to sun. Be sure to look for appropriate packaging to keep your retinol potent.
Using retinol and retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolPropanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Propanediol is not likely to cause sensitivity and considered safe to use.
It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolWe don't have a description for Sodium Cocoamphoacetate.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateThis BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
In cosmetics, butylated hydroxyanisole is used as a perservative. It also has antioxidant properties. The concentrations usually used in skincare are low and do not penetrate through skin.
However, it is considered a carcinogen when ingested.
Butylated Hydroxyanisole is a synthetic and waxy petrochemical. It is used as a preservative in foods and cosmetics.
Learn more about BHAXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumOryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
Oryza Sativa Bran Extract is moisturizing. This is due to its components of polysaccharides and omega-3 fatty acids. It also contains calcium, selenium, phosphorus, iron, and zinc.
Oryza Sativa Bran Extract contains numerous antioxidants such as ferulic acid. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material.
Learn more about Oryza Sativa Bran ExtractRosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, this component is usually removed in the leaf extract.
Rosemary Leaf Extract can help protect your skin against damage from free-radical molecules. It contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid has been found to help soothe skin conditions such as eczema and acne.
Learn more about Rosmarinus Officinalis Leaf ExtractHelianthus Annuus Extract comes from the common sunflower.
Sunflowers are rich in vitamin E. Studies show sunflowers contain antimicrobial and antioxidant properties.
The fatty acids found in sunflowers include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.
These fatty acids hydrate your skin. Emollients create a film on the skin to prevent moisture from escaping.
Learn more about Helianthus Annuus ExtractTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolGuar gum is made from the guar bean, a plant native to India. It is considered a form of polysaccharide and naturally contains sugar.
This ingredient is often used to thicken a product or create a gel-like consistency.
It also has emulsion properties to help keep ingredients together.
Learn more about Cyamopsis Tetragonoloba GumAvena Sativa Bran Extract comes from oatmeal. The bran is the shell covering the oat.
This ingredient is an abrasive, meaning it exfoliates the top layer of your skin.
Citrus Aurantium Dulcis Peel Extract comes from the peels of the bitter orange. This orange is native to Southeast Asia. It is commonly used in foods such as marmalade.
Citrus peels are often made up of mainly limonene. Limonene is a fragrance with a citrus scent. They also contain flavonoids, which have anti-inflammatory properties.
Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
Camellia Sinensis Leaf Extract has many benefits. It contains polyphenols, a strong antioxidant. Antioxidants help fight off free-radical molecules that damage skin cells. The antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.
Many components of tea have anti-inflammatory properties. Polyphenols and L-theanine help soothe the skin and reduce irritation. L-theanine is an amino acid that makes up most of the amino acids found in tea leaves. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.
Camellia Sinensis Leaf Extract also contains Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.
Camellia Sinensis Leaf Extract also has antimicrobial properties.
Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.
Learn more about Camellia Sinensis Leaf ExtractTetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
AAVC is able to increase the consistency and viscosity of products due to its large molecule size. It also prevents ingredients from separating.
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and look more even.
Read more about some other popular AHA's here:
Learn more about Citric AcidParfum is a catch-all term for an ingredient or more that is used to give aroma to products. Parfum, or fragrance, can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "Parfum" in the ingredients list is a different mixture.
In the US, the alternative name for parfum is 'fragrance'. The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance. One example is Calendula flower extract. Essential oil ingredients still impart a scent or 'fragrance'.
Depending on the blend, it can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Products use parfum often to give products a scent or cover up smells of different ingredients.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
In food, Maltodextrin is used to improve the texture and thicken a product. Due to its structure, it can help create a gel texture. As an emulsion stabilizer, it helps keep the ingredients in a product together.
As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.
Maltodextrin is water soluble and has a sweet taste.
Learn more about MaltodextrinCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.
As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.
Hexylene Glycol has a small molecular weight.
Learn more about Hexylene GlycolButylphenyl Methylpropional is a synthetic fragrance. You might know it as "lilial". The scent of this ingredient is floral-like and similar to the scent of lily flowers.
In March of 2022, the EU banned this ingredient in both rinse-off and leave-on products. This is because research found Butylphenyl Methylpropional to disrupt fertility in rats.
This ingredient is also a known EU allergen, meaning it is likely to cause an allergic reaction. Irritated skin can be damaging.
We always recommend speaking with a professional if you have any concerns or questions about this ingredient.
Learn more about Butylphenyl MethylpropionalLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Linalool has the same effect as Limonene when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
Linalool has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneCitronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
Since the Citronellol molecule is already unstable, Citronellol becomes irritating on the skin when exposed to air.
Citronellol is a modified terpene. Terpenes are unsaturated hydrocarbons found in plants. They make up the primary part of essential oils.
Citronellol is not able to be absorbed into deeper layers of the skin. It has low permeability,
Citronellol is also a natural insect repellent.
Learn more about CitronellolBeautiful widgets for your website
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