Millefee Dewy Fit Gloss
A lip gloss with 38 ingredients, including vitamin E, hyaluronic acid, and peptides.
Overview
What it is
Lip gloss with 38 ingredients that contains hyaluronic acid, peptides and Vitamin E
Cool Features
It is vegan and cruelty-free
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, parabens or sulfates
Fun facts
Millefee is from Japan.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Polyisobutene
Pentaerythrityl Tetraisostearate
EmollientTridecyl Trimellitate
EmollientIsononyl Isononanoate
EmollientHydrogenated Polydecene
EmollientHydrogenated Styrene/Isoprene Copolymer
Phenyl Trimethicone
Skin ConditioningSilica Dimethyl Silylate
EmollientMenthol
MaskingTitanium Dioxide
Cosmetic ColorantCaprylyl Glycol
EmollientMenthone Glycerin Acetal
RefreshingMenthyl Lactate
MaskingPolyglyceryl-2 Triisostearate
EmulsifyingParfum
MaskingCI 45380
Cosmetic ColorantEthylhexylglycerin
Skin ConditioningTocopheryl Acetate
AntioxidantIron Oxides
CI 19140
Cosmetic ColorantTriethoxycaprylylsilane
Limnanthes Alba Seed Oil
Skin ConditioningRosa Canina Fruit Oil
EmollientCarum Carvi Fruit Oil
MaskingCaprylic/Capric Triglyceride
MaskingEthylhexyl Palmitate
EmollientPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantPolyhydroxystearic Acid
EmulsifyingRicinus Communis Seed Oil
MaskingAminopropyl Triethoxysilane
SurfactantSodium Hyaluronate
HumectantTribehenin
EmollientHydrogenated Castor Oil
EmollientTocopherol
AntioxidantSorbitan Isostearate
EmulsifyingCamellia Sinensis Extract
AntioxidantLactic Acid
BufferingPalmitoyl Tripeptide-1
Skin ConditioningPolyisobutene, Pentaerythrityl Tetraisostearate, Tridecyl Trimellitate, Isononyl Isononanoate, Hydrogenated Polydecene, Hydrogenated Styrene/Isoprene Copolymer, Phenyl Trimethicone, Silica Dimethyl Silylate, Menthol, Titanium Dioxide, Caprylyl Glycol, Menthone Glycerin Acetal, Menthyl Lactate, Polyglyceryl-2 Triisostearate, Parfum, CI 45380, Ethylhexylglycerin, Tocopheryl Acetate, Iron Oxides, CI 19140, Triethoxycaprylylsilane, Limnanthes Alba Seed Oil, Rosa Canina Fruit Oil, Carum Carvi Fruit Oil, Caprylic/Capric Triglyceride, Ethylhexyl Palmitate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Ricinus Communis Seed Oil, Aminopropyl Triethoxysilane, Sodium Hyaluronate, Tribehenin, Hydrogenated Castor Oil, Tocopherol, Sorbitan Isostearate, Camellia Sinensis Extract, Lactic Acid, Palmitoyl Tripeptide-1
Key Ingredients
Benefits
Concerns
Ingredients Explained
Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobutenePentaerythrityl Tetraisostearate is a synthetic emollient and "skin-feel" ingredient that spreads well and leaves a non-sticky finish with high gloss.
In makeup, it also doubles as a pigment-wetting agent for better color payoff.
It's a well-vetted ingredient for safety and does not penetrate into skin due to its large molecule size.
Because it's a long-chain fatty acid ester, this ingredient may not be fungal acne or Malassezia safe.
Learn more about Pentaerythrityl TetraisostearateTridecyl Trimellitate is a synthetic ingredient with emollient and skin conditioning properties. It also acts as a texture enhancer and helps products spread easily without feeling greasy.
As an emollient, it forms a light layer on the skin that keeps moisture in and improves water resistance. This is why you'll often find this ingredient in eye creams and other rich treatments.
This ingredient is seen as the elegant alternative to mineral oil.
Learn more about Tridecyl TrimellitateIsononyl Isononanoate is a synthetic skin-conditioner and texture enhancer. It is created from nonanoic acid, a fatty acid found in cocoa and lavender oil.
As an emollient, Isononyl Isononanoate helps keep your skin soft and smooth. This is because emollients create a barrier on the skin to trap moisture in.
Isononyl Isononanoate helps give products a velvet feel and improves spreadability.
Learn more about Isononyl IsononanoateHydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.
In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.
Learn more about Hydrogenated PolydeceneWe don't have a description for Hydrogenated Styrene/Isoprene Copolymer yet.
Phenyl Trimethicone is a silicon-based polymer. It is derived from silica.
Phenyl Trimethicone is used as an emollient and prevents products from foaming.
As an emollient, it helps trap moisture in the skin. It is considered an occlusive.
Learn more about Phenyl TrimethiconeThis silica is mainly used to thicken oils and suspend particles in oils. It is not water soluble.
According to the manufacturer, it:
The manufacturer also claims this ingredient to be useful in makeup.
In lipstick formulations, this ingredient improves color payoff, reduces pigment settling, and reduces oil bleeding. This ingredient also improves the grip of powder products such as dry shampoos.
Learn more about Silica Dimethyl SilylateMenthol is a compound found in mint plants, such as peppermint. In its pure form, it is a clear crystalline substance.
Menthol is known for its cooling sensation; however, the cooling is actually from your skin being sensitized. Menthol can worsen rosacea. We recommend speaking with a professional if you have concerns.
Menthol also has antimicrobial properties.
Learn more about MentholTitanium dioxide is a mineral UV filter widely used in sunscreens and cosmetics.
It is one of only two UV filters officially classified as âmineralâ by regulatory agencies, the other being zinc oxide.
Titanium dioxide provides broad-spectrum protection mostly in the UVB and UVAII range, with some protection in the UVAI range.
While its UVA protection isnât as strong as zinc oxideâs, the difference is minor.
A common myth is that mineral UV filters reflect UV light. However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).
Thanks to its non-irritating nature, titanium dioxide is suitable for sensitive, acne-prone, or redness-prone skin. It is unlikely to cause "eye sting" like other sunscreen ingredients.
A major drawback of this ingredient is its white cast and thick texture. This is why mineral sunscreens often leave a white cast and are less cosmetically elegant than chemical/hybrid sunscreens.
To improve white cast and spreadability, micronized or nano-sized titanium dioxide is often used.
There are ongoing concerns surrounding nano-titanium oxide's impact on marine ecosystems.
There is no conclusive evidence that any form of titanium oxide (or any other sunscreen ingredients) will cause harm to marine ecosystems or coral reefs. The science is still developing but many consumers are keeping a close eye on this issue.
Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.
Nano mineral sunscreens once raised safety concerns about absorption into skin.
Extensive research has shown that they do not penetrate healthy or damaged skin; they remain safely on the surface and the top layer of dead skin (stratum corneum).
You'll likely find titanium dioxide bundled with alumina, silica, or dimethicone. These ingredients help make titanium dioxide highly photostable; this prevents it from interacting with other formula components under UV light.
Learn more about Titanium DioxideCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolMenthone Glycerin Acetal can worsen rosacea.
Menthyl lactate is an ester of menthol and lactic acid. It is often used as a cooling agent and fragrance.
When applied topically, this ingredient leaves a refreshing sensation like menthol, but is less irritating.
Polyglyceryl-2 Triisostearate is a plant-derived emulsifier and pigment-dispersing agent with a non-sticky skin feel.
It helps products glide on smoothly and prevents oil and water from separating in a formula, making it suitable for sunscreen and makeup formulations.
The EU inventory of cosmetics has no use restrictions on this ingredient and it is considered well-tolerated.
This ingredient may not be fungal acne safe because it is derived from isostearic acid.
Learn more about Polyglyceryl-2 TriisostearateParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of âFRAGRANCEâ or âPARFUMâ according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumCi 45380 is a synthetic dye that comes from coal or tar sources. Due to this, it is often used in small quantities.
A common name for this dye is Red 22. Red 22 imparts a warm reddish color.
Similar to Red 27, this dye changes color based on pH and moisture levels.
This dye is colorless when dry but turns pink between pH levels 0.0 to ~3.0.
Learn more about CI 45380Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateThis ingredient is a combination of red, black, and yellow iron oxide pigments. This combination of colors is usually found in foundation, because it results in a "skin" color.
The EU typically uses CI numbers for colorants when applicable, such as CI 77489. In the US, iron oxides are regulated as color additives and "iron oxides" is the most commonly used name in US cosmetic practice.
A 2021 paper looked at skincare formulations containing iron oxides and found that they reduced transmission of blue light when measured optically. In simple terms, the pigment particles helped block or scatter part of the visible light spectrum in lab testing and the authors suggest this could translate into better protection against blue-light-related skin effects.
There is also clinical and experimental research showing that tinted products containing iron oxides can reduce visible light-induced pigmentation:
Please note, whether a product reduces visible or blue light depends on things like:
In the EU's CosIng database, iron oxides are only listed as a colorant. CosIng groups ingredients by their main cosmetic role, such as colorant, preservative, or UV filter.
Though studies say iron oxides can "attenuate blue light", they're describing an optical property and not an officially recognized cosmetic function.
So CosIng isnât contradicting the research. Itâs just classifying iron oxides by what they officially are: pigments that add color.
Learn more about Iron OxidesCI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Learn more about CI 19140Triethoxycaprylylsilane is a silicon-based surface modifier that makes sunscreens feel silky and makeup stay put.
Its main job is to coat mineral particles like titanium dioxide, zinc oxide, and color pigments in a thin, oily layer so they spread smoothly, don't clump, and stick to skin better.
This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).
Learn more about TriethoxycaprylylsilaneLimnanthes Alba Seed Oil is from the seeds of the meadowfoam plant. It is a skin conditioning agent and emollient that sits on top of skin to soften and hydrate it.
Over 98% of the oil is made up of long-chain fatty acids, mostly aachidic acid (61%), docosenoic acid (~16%), and docosadienoic acid (~18%).
This combination is not really found in any other plant oil and is the reason this is one of the most stable botanical oils available.
Some studies show it to be more stable than jojoba oil, helps a product resist going rancid, and can help extend the shelf life of a formula.
It also naturally contains vitamin E and phytosterols that give it a mild antioxidant benefit.
This ingredient is typically used from around 1% to fairly high levels since it's gentle; it's well-tolerated and low on the irritation scale.
Learn more about Limnanthes Alba Seed OilRosehip Oil is a non-fragrant plant oil. Rosehips are a fruit from a rose bush and are edible. This oil has skin conditioning and hydrating properties.
Rosehip contains Vitamin C, Vitamin E, fatty acids and linolenic acids. These nourish your skin barrier. Having hydrated skin may help reduce the appearance of fine-lines and wrinkles.
Another great component of Rosehip Oil is Vitamin A, or retinol. Vitamin A encourages your skin to create more collagen.
Rosehip oil may help with reducing pigmentation. The lycopene and beta-carotene have skin-lightening properties. However, more studies are needed to confirm this.
Learn more about Rosa Canina Fruit OilCarum Carvi Fruit Oil is a fragrance and is an oil.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredientâs final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideEthylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.
In cosmetics, it plays many roles:
One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.
For most people, this is a well-tolerated and lightweight ingredient.
This ingredient may not be fungal acne safe because it is a fatty acid ester.
Learn more about Ethylhexyl PalmitatePentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
It is used to help stabilize other antioxidants or prevent the color from changing in a product.
As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.
This ingredient is oil-soluble.
Learn more about Pentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamatePolyhydroxystearic Acid is a vegetable-derived soft wax made from castor oil. It's an emulsion stabilizer, thickener, and film former.
You'll likely see it in sunscreens because it helps disperse pigments and UV-reflecting minerals like titanium dioxide and zinc oxide evenly.
Depending on the concentration, it can drastically change the texture of a product from pasty solid (like lipstick) to sprayable liquid.
The CIR Expert Panel for Cosmetic Ingredient Safety has concluded this ingredient to be safe in cosmetics. The highest reported use concentration is 14.2% in lipsticks.
Learn more about Polyhydroxystearic AcidThis ingredient is also known as castor oil. It is a skin conditioning ingredient.
The star component of castor oil is ricinoleic acid, an unusual fatty acid that makes up ~80-92% of its composition.
In skincare, it is an emollient that dries down to a solid film with water-binding properties. This helps keep skin hydrated and helps reduce transepidermal water loss (TEWL).
A 2026 dermatology review pulls together its broader uses:
Human clinical testing found this ingredient to be non-irritating and non-sensitizing.
Because castor oil contains fatty acids in the C11-24 range, this ingredient may not be fungal acne safe.
At this time, the literature does not support castor oil in regrowing hair. A 2022 systematic review found no strong evidence that it supports hair growth and only weak evidence that it improves hair shine.
Castor oil itself carries "perfuming" and "masking" function tags according to the official CosIng database. This is because of its mild odor and odor-dampening properties.
Learn more about Ricinus Communis Seed OilWe don't have a description for Aminopropyl Triethoxysilane yet.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateTribehenin is the triglyceride of glycerin and behenic acid. It is an emollient that helps soften and condition skin.
Safety-wise, this is a well-vetted ingredient. Repeated-insult patch tests of 0.38% tribehenin did not trigger sensitization.
This ingredient may not be fungal acne safe because behenic acid falls into the chain-length range that Malassezia yeasts can feed on.
Learn more about TribeheninHydrogenated Castor Oil (aka "castor wax") is what you get when castor oil is turned into a wax.
Its dominant fatty acid is ricinoleic acid, giving it both emollient and mild humectant properties.
According to EU CosIng, this ingredient helps soften skin, keep oil and water stay mixed, and thickens products.
Hydrogenated castor oil at 30% did not trigger a positive patch-test reaction and is well-tolerated.
Since this ingredient is based on an 18-carbon fatty acid, it falls into the chain-length range that Malassezia can feed on and may not be fungal acne safe.
Learn more about Hydrogenated Castor OilTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolSorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Learn more about Sorbitan IsostearateCamellia Sinensis Extract is from the oil in tea plant leaves. The leaves give us various types of tea: green, black, oolong, and white.
Camellia Sinensis leaves have many benefits. It contains polyphenols, a strong antioxidant. Antioxidants help fight off free-radical molecules that damage skin cells. The antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.
Many components of tea have anti-inflammatory and antimicrobial properties. Polyphenols and L-theanine help soothe the skin and reduce irritation. L-theanine is an amino acid that makes up most of the amino acids found in tea leaves. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.
Tea leaves also contain Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.
Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.
Learn more about Camellia Sinensis ExtractLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the âglueâ that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they donât penetrate as deeply. This means theyâre less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skinâs microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the productâs pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPalmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
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Where it's from
Millefee is a Japanese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated February 10, 2026 • Added by anemone