Mediheal Derma 365 Mask Madecassoside

Mediheal Derma 365 Mask

Type: Madecassoside
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Overview

What it is

Sheet mask with 58 ingredients that contains hyaluronic acid and niacinamide

Cool Features

It is vegan and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

It doesn't contain any harsh alcohols, parabens, silicones or sulfates

Fun facts

Mediheal is from South Korea.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

35
14
9

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Dipropylene Glycol

Humectant

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Hydroxyacetophenone

Antioxidant
Antioxidant IconHelps reduce irritation Icon

Aminobutyric Acid

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Ethylhexylglycerin

Skin Conditioning

Styrene/Acrylates Copolymer

Xanthan Gum

Emulsifying

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Carbomer

Emulsion Stabilising
1 / 0

Pantolactone

Humectant
Helps hydrate Dry Skin Icon

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Polyglyceryl-4 Laurate

Emulsifying
Not safe for Fungal Acne Icon

Disodium EDTA

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Glyceryl Glucoside

Humectant
Helps hydrate Dry Skin Icon

Pearl Extract

Antioxidant
Antioxidant Icon

Juniperus Virginiana Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Rosa Damascena Flower Water

Masking
Helps reduce irritation Icon

Glutamic Acid

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Mel Extract

Moisturising

Iris Florentina Root Extract

Masking

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Cymbopogon Schoenanthus Extract

Skin Conditioning

Simmondsia Chinensis Seed Oil

Emollient
0-2 / 0 Oil IconHelps hydrate Dry Skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Tranexamic Acid

Astringent
Helps reduce irritation IconGood for Dark Spots IconGood for Scar Healing Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Hedera Helix Leaf/Stem Extract

Antimicrobial

Bambusa Vulgaris Leaf Extract

Skin Conditioning

Linum Usitatissimum Seed Extract

Perfuming
Fragrance Icon

Tremella Fuciformis Polysaccharide

Emulsion Stabilising
Helps hydrate Dry Skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Pantothenic Acid

Skin Conditioning

Sodium Polyacrylate

Absorbent
Helps hydrate Dry Skin Icon

Pogostemon Cablin Leaf Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Sodium Chloride

Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon

Artemisia Vulgaris Oil

Perfuming
Fragrance IconOil Icon

Rosmarinus Officinalis Leaf Oil

Masking
Oil Icon

Histidine

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Serine

Masking
Helps hydrate Dry Skin Icon

Alanine

Masking

Proline

Skin Conditioning

Threonine

Helps hydrate Dry Skin Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Magnesium Chloride

Calcium Chloride

Astringent

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Asiatic Acid

Skin Conditioning

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

It is a humectant and helps add texture to products. It can make your product thicker.

As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.

Learn more about Glycereth-26
Humectant, Masking, Solvent

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the โ€˜goodโ€™ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservativesย 
Antioxidant

Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.

This ingredient is not irritating or sensitizing.

Aminobutyric Acid is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies have shown Gamma-Aminobutyric Acid may reduce hyperpigmentation.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

We don't have a description for Styrene/Acrylates Copolymer yet.

Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Humectant, Skin Conditioning

Pantolactone is a synthetically created humectant.

As a humectant, Pantolactone helps draw moisture to the skin. It can help add hydration to your skin.

Masking, Skin Conditioning

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Skin Conditioning

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.

Polyglyceryl-10 Laurate may not be fungal acne safe.

Learn more about Polyglyceryl-10 Laurate
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract

Polyglyceryl-4 Laurate isn't fungal acne safe.

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Learn more about Trehalose
Humectant, Skin Conditioning

Glyceryl Glucoside is made from glycerol and glucose.

It is a humectant. Humectants help hydrate your skin by drawing moisture to it from the air.

Some foods that contain glyceryl glucoside include sake, miso, and wines.

Learn more about Glyceryl Glucoside
Antioxidant

Pearl Extract comes from, well, pearls. Pearls are harvested from oysters.

Pearls are rich in amino-acids, magnesium, potassium, calcium, and antioxidant compounds.

Two antioxidants found in pearls include: superoxide dismutase (SOD) and glutathione. Antioxidants aid in reducing the signs of aging.

Studies show pearls can aid in wound healing.

Pearls are harvested from oysters. To be vegan, an ingredient cannot be from an animal source.

Learn more about Pearl Extract
Masking, Tonic

Juniperus Virginiana Oil is the volatile oil obtained from the fruits and leaves of the Red Cedar tree. This tree is native to North America.

Skin Conditioning

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.

Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.

The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.

Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.

This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Leaf Extract
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Buffering, Skin Conditioning

This ingredient is an amino acid that helps build proteins and moisturizes skin. It is already present in our skin as our bodies produce them naturally.

Glycine already plays a role in helping keep our skin moisturized as amino acids transport moisture throughout our skin.

As collagen is made up of glycine and other amino acids, it is believed glycine may help our skin produce more collagen.

Learn more about Glycine
Masking, Skin Conditioning, Skin Protecting

Rosa Damascena Flower Water comes from the Damask rose. It is a dilluted version of the Rose Essential oil.

The Damask Roses' petals have antioxidant, antimicrobial, and fragrance compounds. Though antioxidants are great for soothing skin, the fragrance compounds can irritate it.

Humectant

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Learn more about Glutamic Acid
Moisturising

We don't have a description for Mel Extract yet.

We don't have a description for Iris Florentina Root Extract yet.

Masking, Skin Conditioning

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.

Skin Conditioning, Soothing

Cymbopogon Schoenanthus Extract is created from Lemongrass. Lemongrass is native to southern Asia and northern Africa.

Lemongrass has antibacterial and antioxidant properties. However, it also contains fragrance components that may sensitize skin, limonene and citral.

Emollient, Skin Conditioning

This oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.

Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.

It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.

This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.

While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.

Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.

Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.

Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.

Learn more about Simmondsia Chinensis Seed Oil
Astringent, Skin Conditioning

Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.

Once applied, Tranexamic Acid starts decreasing inflammation from UV exposure. Tranexamic Acid also prevents our skin cells from meeting the pigment production cells.

Its brightening property makes it great at reducing the appearance of acne scars and marks.

Fun fact: Tranexamic Acid is also a medication used to reduce heavy bleeding.

This acid is derived from lysine, an amino acid.

Learn more about Tranexamic Acid
Antioxidant, Skin Conditioning

Madecassoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Madecassoside has antioxidant, anti-inflammatory, and hydrating properties. It contains fatty acids, amino acids, beta-carotene, and phytochemicals.

One study found using Madecassoside with ascorbic acid helped reduce the signs of aging and improved skin hydration.

Learn more about Madecassoside
Antimicrobial, Astringent, Skin Conditioning

We don't have a description for Hedera Helix Leaf/Stem Extract yet.

Skin Conditioning

Bambusa Vulgaris Leaf Extract comes from bamboo plant.

Bamboo leaf extract has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

A recent study found bamboo extract might interrupt the process of hyperpigmentation.

Learn more about Bambusa Vulgaris Leaf Extract
Perfuming, Skin Conditioning

Linum Usitatissimum Seed Extract is a fragrance.

Emulsion Stabilising, Skin Conditioning

Tremella Fuciformis Polysaccharide are the sugars from the snow mushroom.

Snow mushroom is rich in polysaccharides, giving it moisturizing benefits. As a humectant, snow mushroom helps draw moisture from the air to the skin. Polysaccharides are able to mimic our skin's natural carbohydrates to help the skin retain water.

Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning

Pantothenic Acid is an essential vitamin. Our bodies use it for metabolizing fatty acids, proteins, carbohydrates, and fats.

Absorbent, Emollient, Emulsion Stabilising

Sodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.

This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.

This ingredient is commonly known as Patchouli oil.

Patchouli exhibits slight antibacterial and antifungal activity from its patchoulol and alpha-patchoulene content.

However, it also contains known skin-irritating fragrances. A study from 2015 found limonene and camphor as active components of this ingredient.

Limonene and camphor are both known EU allergens.

Learn more about Pogostemon Cablin Leaf Oil
Masking

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.

This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.

You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.

There is much debate on whether this ingredient is comedogenic. The short answer - comedogenic ratings don't tell the whole story. Learn more about comegodenic ratings here.

The concensus about this ingredient causing acne seems to be divided. Research is needed to understand if this ingredient does cause acne.

Scrubs may use salt as the primary exfoliating ingredient.

Learn more about Sodium Chloride
Perfuming, Skin Conditioning

Artemisia Vulgaris Oil is a fragrance and is an oil.

Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Oil is oil expressed from the leaves of the rosemary plant.

Rosemary Leaf Oil is a fragrance and helps give your product a scent. If you are sensitive to irritating fragrances, this one contains camphor. Camphor has been found to irritate skin.

This oil also contains antioxidant and antimicrobial properties. As an antioxidant, it may protect you skin against damage. This can help slow down the signs of aging.

Learn more about Rosmarinus Officinalis Leaf Oil
Humectant, Skin Conditioning

Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.

Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.

One study found histidine and carnosine to be a dynamic duo for your skin:

Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.

Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.

Learn more about Histidine
Masking, Skin Conditioning

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine
Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Our skin uses proline as one of the building blocks for producing collagen.

In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.

Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.

Learn more about Proline

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.

We don't have a description for Magnesium Chloride yet.

Astringent

Calcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.

This ingredient is highly soluble in water, acetic acid, and ethanol.

There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.

Learn more about Calcium Chloride
Antioxidant, Skin Conditioning

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Asiaticoside is an antioxidant and helps with wound healing. It has been shown to increase antioxidant activity during the wound healing process.

Skin Conditioning, Stabilising

Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.

Studies show Asiatic Acid is able to block the pathway for skin inflammation receptors, helping to soothe skin.

As an antioxidant, asiatic acid helps protect our skin against damaging environmental factors.

Learn more about Asiatic Acid
Skin Conditioning

Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.

It is a triterpenoid, meaning it naturally acts as an antioxidant. Antioxidants protect your skin against damage from environmental factors such as pollution and UV.

Studies show Madecassic Acid helps soothe the skin due to its ability to block inflammation pathways.

Learn more about Madecassic Acid

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Where it's from

Mediheal is a Korean brand

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ยท Updated October 8, 2025 Added by AlienVal