Peter Thomas Roth Peptide Skinjection Fill + Fix Under-Eye Cream Versus MediCube PDRN Pink Peptide Eye Cream
This anti-aging eye moisturizer is formulated around Caffeine and Sodium Hyaluronate to soften the look of wrinkles and hydrate skin.
This anti-aging eye moisturizer is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
EmollientButylene Glycol
HumectantCetyl PEG/PPG-10/1 Dimethicone
EmulsifyingGlycerin
HumectantPolysilicone-11
Bellis Perennis Flower Extract
Skin ConditioningPEG/PPG-18/18 Dimethicone
EmulsifyingSh-Pentapeptide-5
Skin ConditioningHieracium Pilosella Extract
MaskingCaffeine
Skin ConditioningSodium Hyaluronate
HumectantPotassium Glutathione Isomerized Linoleate
Glucomannan
Skin ConditioningSodium Chloride
MaskingSilica
AbrasiveSilica Silylate
EmollientSodium Citrate
BufferingCitric Acid
BufferingTrihydroxystearin
Skin ConditioningEthylhexyl Palmitate
EmollientLauryl Glucoside
CleansingSodium Benzoate
MaskingEthylhexylglycerin
Skin ConditioningPotassium Chloride
Tetrasodium Glutamate Diacetate
Propylene Glycol
HumectantDecyl Glucoside
CleansingTrisiloxane
Skin ConditioningPotassium Sorbate
PreservativeSodium Dehydroacetate
Preservative1,2-Hexanediol
Skin ConditioningMica
Cosmetic ColorantTriethoxycaprylylsilane
Titanium Dioxide
Cosmetic ColorantIron Oxides
CI 77492
Cosmetic ColorantCI 77491
Cosmetic ColorantPhenoxyethanol
PreservativeWater, Dimethicone, Butylene Glycol, Cetyl PEG/PPG-10/1 Dimethicone, Glycerin, Polysilicone-11, Bellis Perennis Flower Extract, PEG/PPG-18/18 Dimethicone, Sh-Pentapeptide-5, Hieracium Pilosella Extract, Caffeine, Sodium Hyaluronate, Potassium Glutathione Isomerized Linoleate, Glucomannan, Sodium Chloride, Silica, Silica Silylate, Sodium Citrate, Citric Acid, Trihydroxystearin, Ethylhexyl Palmitate, Lauryl Glucoside, Sodium Benzoate, Ethylhexylglycerin, Potassium Chloride, Tetrasodium Glutamate Diacetate, Propylene Glycol, Decyl Glucoside, Trisiloxane, Potassium Sorbate, Sodium Dehydroacetate, 1,2-Hexanediol, Mica, Triethoxycaprylylsilane, Titanium Dioxide, Iron Oxides, CI 77492, CI 77491, Phenoxyethanol
Water
Skin ConditioningGlycerin
HumectantDipropylene Glycol
HumectantNiacinamide
SmoothingCaprylic/Capric Triglyceride
MaskingPentaerythrityl Tetraethylhexanoate
EmollientCetearyl Alcohol
EmollientGlycereth-26
HumectantButylene Glycol Dicaprylate/Dicaprate
EmollientBis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate
EmollientCetearyl Olivate
Sorbitan Olivate
EmulsifyingPropylene Glycol Dibenzoate
Skin ConditioningPullulan
1,2-Hexanediol
Skin ConditioningGlyceryl Stearate
EmollientVinyldimethicone
Hydroxyacetophenone
AntioxidantHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydrogenated Lecithin
EmulsifyingSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingSodium DNA
Skin ConditioningPolyisobutene
Butylene Glycol
HumectantEthylhexylglycerin
Skin ConditioningPropanediol
SolventMelia Azadirachta Leaf Extract
Skin ConditioningAdenosine
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningCurcuma Longa Root Extract
AntioxidantSorbitan Isostearate
EmulsifyingSorbitan Oleate
EmulsifyingCaprylyl/Capryl Glucoside
CleansingFragaria Chiloensis Fruit Extract
Skin ConditioningHedera Helix Leaf/Stem Extract
AntimicrobialCyanocobalamin
Skin ConditioningCitrus Nobilis Peel Extract
MaskingRetinol
Skin ConditioningOcimum Sanctum Leaf Extract
Skin ConditioningLespedeza Capitata Leaf/Stem Extract
Skin ConditioningCorallina Officinalis Extract
Skin ConditioningSodium Hyaluronate
HumectantCaffeine
Skin ConditioningCoffea Arabica Seed Extract
MaskingHydrolyzed Extensin
Skin ConditioningHydrolyzed Hyaluronic Acid
HumectantCopper Tripeptide-1
Skin ConditioningSodium Acetylated Hyaluronate
HumectantAcetyl Hexapeptide-8
HumectantPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningWater, Glycerin, Dipropylene Glycol, Niacinamide, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Cetearyl Alcohol, Glycereth-26, Butylene Glycol Dicaprylate/Dicaprate, Bis-Behenyl/Isostearyl/Phytosteryl Dimer Dilinoleyl Dimer Dilinoleate, Cetearyl Olivate, Sorbitan Olivate, Propylene Glycol Dibenzoate, Pullulan, 1,2-Hexanediol, Glyceryl Stearate, Vinyldimethicone, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Polyisobutene, Butylene Glycol, Ethylhexylglycerin, Propanediol, Melia Azadirachta Leaf Extract, Adenosine, Melia Azadirachta Flower Extract, Curcuma Longa Root Extract, Sorbitan Isostearate, Sorbitan Oleate, Caprylyl/Capryl Glucoside, Fragaria Chiloensis Fruit Extract, Hedera Helix Leaf/Stem Extract, Cyanocobalamin, Citrus Nobilis Peel Extract, Retinol, Ocimum Sanctum Leaf Extract, Lespedeza Capitata Leaf/Stem Extract, Corallina Officinalis Extract, Sodium Hyaluronate, Caffeine, Coffea Arabica Seed Extract, Hydrolyzed Extensin, Hydrolyzed Hyaluronic Acid, Copper Tripeptide-1, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Learn more about CaffeineEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water