Neutrogena Hydro Boost Hydrating Fluid SPF 50 Versus La Roche-Posay Anthelios UVMune 400 Anti Dark-Spot Fluid SPF 50+
This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialEthylhexyl Triazone
UV AbsorberDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterCaprylyl Methicone
Skin ConditioningDiisopropyl Adipate
EmollientAluminum Starch Octenylsuccinate
AbsorbentMethylene Bis-Benzotriazolyl Tetramethylbutylphenol
UV FilterNiacinamide
SmoothingDimethicone
EmollientDiisopropyl Sebacate
EmollientGlycerin
HumectantGlyceryl Stearate
EmollientPEG-100 Stearate
SurfactantHydroxyacetophenone
AntioxidantBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningPotassium Cetyl Phosphate
EmulsifyingTriacontanyl Pvp
HumectantDecyl Glucoside
CleansingDimethicone Crosspolymer
Emulsion StabilisingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydrolyzed Jojoba Esters
Skin ConditioningTitanium Dioxide
Cosmetic ColorantSodium Ascorbyl Phosphate
AntioxidantDisodium EDTA
Tocopheryl Acetate
AntioxidantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPentylene Glycol
Skin ConditioningPanthenol
Skin ConditioningSilica
AbrasiveSodium Hyaluronate
HumectantJojoba Esters
EmollientSodium Hydroxide
BufferingPropylene Glycol
HumectantPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingXanthan Gum
EmulsifyingWater, C12-15 Alkyl Benzoate, Ethylhexyl Triazone, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Caprylyl Methicone, Diisopropyl Adipate, Aluminum Starch Octenylsuccinate, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Niacinamide, Dimethicone, Diisopropyl Sebacate, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Hydroxyacetophenone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Potassium Cetyl Phosphate, Triacontanyl Pvp, Decyl Glucoside, Dimethicone Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Jojoba Esters, Titanium Dioxide, Sodium Ascorbyl Phosphate, Disodium EDTA, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Pentylene Glycol, Panthenol, Silica, Sodium Hyaluronate, Jojoba Esters, Sodium Hydroxide, Propylene Glycol, Polysorbate 60, Sorbitan Isostearate, Xanthan Gum
Water
Skin ConditioningAlcohol Denat.
AntimicrobialSilica
AbrasiveDiisopropyl Adipate
EmollientDiisopropyl Sebacate
EmollientEthylhexyl Triazone
UV AbsorberButyl Methoxydibenzoylmethane
UV AbsorberBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningDicaprylyl Carbonate
EmollientGlycerin
HumectantPropanediol
SolventC12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer
StabilisingDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterC12-15 Alkyl Benzoate
AntimicrobialMethoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
StabilisingPerlite
AbsorbentDrometrizole Trisiloxane
UV AbsorberAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCitric Acid
BufferingDisodium Phosphate
BufferingHydroxyacetophenone
AntioxidantHydroxyethylcellulose
Emulsion Stabilising2-Mercaptonicotinoyl Glycine
Skin ConditioningPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantPentylene Glycol
Skin ConditioningPolysorbate 60
EmulsifyingSodium Phosphate
BufferingSodium Thiosulfate
Terephthalylidene Dicamphor Sulfonic Acid
UV AbsorberTocopherol
AntioxidantTriethanolamine
BufferingTrisodium Ethylenediamine Disuccinate
Water, Alcohol Denat., Silica, Diisopropyl Adipate, Diisopropyl Sebacate, Ethylhexyl Triazone, Butyl Methoxydibenzoylmethane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Dicaprylyl Carbonate, Glycerin, Propanediol, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Diethylamino Hydroxybenzoyl Hexyl Benzoate, C12-15 Alkyl Benzoate, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate, Perlite, Drometrizole Trisiloxane, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Citric Acid, Disodium Phosphate, Hydroxyacetophenone, Hydroxyethylcellulose, 2-Mercaptonicotinoyl Glycine, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Pentylene Glycol, Polysorbate 60, Sodium Phosphate, Sodium Thiosulfate, Terephthalylidene Dicamphor Sulfonic Acid, Tocopherol, Triethanolamine, Trisodium Ethylenediamine Disuccinate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerThis ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.
It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.
Another pro?
It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.
That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.
Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).
On maximum concentrations:
In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineC12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long.
In cosmetics, it plays several roles:
The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility.
This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product.
It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own.
Overall, this ingredient is well tolerated.
This ingredient is fungal acne safe because it is an ester of benzoic acid.
Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food.
Benzoic acid is actually used as a preservative to stop yeast from growing.
The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well).
In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond.
So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth.
Learn more about C12-15 Alkyl BenzoateDiethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).
DHHB is well-liked for:
DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.
This ingredient is soluble in oils, fats, and lipids.
Learn more about Diethylamino Hydroxybenzoyl Hexyl BenzoateDiisopropyl Adipate comes from isopropyl alcohol and Adipic Acid.
It is a solvent and emollient. As a solvent, it is used to help other ingredients dissolve into the solution. It is also often used to soften hard ingredients.
Emollients help hydrate the skin by creating a thin barrier. This thin barrier prevents moisture from escaping.
Learn more about Diisopropyl AdipateWe don't have a description for Diisopropyl Sebacate yet.
Ethylhexyl Triazone (aka Octyl Triazone) is an oil-soluble organic UVB filter. It has peak absorption around 314 nm, right in the middle of the UVB range.
This ingredient is described as one of the most effective UVB filters available and small concentrations are enough to deliver a high SPF thanks to its strong UV absorbing power.
Formulators love it for its stability; its ability to filter UV stays practically unchanged even under intense radiation and it can also help boost the photostability of less stable filters like avobenzone.
It's also a great pick for water resistant products because it's insoluble in water and has a good affinity for keratin.
Because it's a big, heavy molecule, the European Scientific Committee has found to to have very low dermal penetration and negative results for allergenicity.
In vitro testing also showed a low absorption rate and clean results on irritation.
Typical use levels are 1-5% with 5% being the maximum in the EU, Japan, and other markets that allow it. However, this ingredient is not approved yet in the US or Canada.
Learn more about Ethylhexyl TriazoneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenonePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water