Mesoestetic Melan Tran3x Concentrate Versus Paula's Choice RESIST Advanced Smoothing Treatment 10% AHA
This brightening treatment is formulated around Niacinamide and Mandelic Acid to fade the look of dark spots and brighten dull-looking skin.
This smoothing treatment is formulated around Glycolic Acid and Lactic Acid to refine skin texture and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBis-PEG-12 Dimethicone
Emollient
Butylene Glycol
Humectant
Hydroxyethyl Urea
Humectant
Niacinamide
Smoothing
Mandelic Acid
Antimicrobial
Polymethylsilsesquioxane
Tranexamic Acid
Astringent
Lactic Acid
Buffering
Sodium Citrate
BufferingSodium Hydroxide
BufferingKojic Acid
Antioxidant
Plankton Extract
Skin ConditioningBacillus Ferment
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Skin ConditioningGlycogen
HumectantEthylhexylglycerin
Skin ConditioningPropylene Glycol
Humectant
Glycerin
Humectant
Salicylic Acid
Masking
Citric Acid
Buffering
Xanthan Gum
EmulsifyingPolyacrylate Crosspolymer-11
Emulsion StabilisingAminoethylphosphinic Acid
Skin ConditioningDisodium EDTA
Sclerotium Gum
Emulsion StabilisingLecithin
Emollient
Pullulan
Pentylene Glycol
Skin Conditioning
Sodium Hyaluronate Crosspolymer-2
HumectantSilica
Abrasive
Potassium Sorbate
Preservative
Sodium Metabisulfite
Antioxidant
Phenoxyethanol
Preservative
Parfum
Masking
Water, Bis-PEG-12 Dimethicone, Butylene Glycol, Hydroxyethyl Urea, Niacinamide, Mandelic Acid, Polymethylsilsesquioxane, Tranexamic Acid, Lactic Acid, Sodium Citrate, Sodium Hydroxide, Kojic Acid, Plankton Extract, Bacillus Ferment, Acetyl Glycyl Beta-Alanine, Glycogen, Ethylhexylglycerin, Propylene Glycol, Glycerin, Salicylic Acid, Citric Acid, Xanthan Gum, Polyacrylate Crosspolymer-11, Aminoethylphosphinic Acid, Disodium EDTA, Sclerotium Gum, Lecithin, Pullulan, Pentylene Glycol, Sodium Hyaluronate Crosspolymer-2, Silica, Potassium Sorbate, Sodium Metabisulfite, Phenoxyethanol, Parfum
Water
Skin ConditioningButylene Glycol
Humectant
Glycolic Acid
Buffering
Glycerin
Humectant
Lactic Acid
Buffering
Caprylic/Capric Triglyceride
Masking
Malic Acid
Buffering
Tartaric Acid
Buffering
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide Ng
Skin Conditioning
Salicylic Acid
Masking
Glycyrrhiza Glabra Root
Skin ConditioningCamellia Sinensis Leaf Extract
Antimicrobial
Punica Granatum Extract
AstringentLycium Barbarum Fruit Extract
Astringent
Vitis Vinifera Seed Extract
Antimicrobial
Sambucus Nigra Fruit Extract
AstringentCamellia Oleifera Leaf
MaskingChamomilla Recutita Flower Extract
Masking
Peucedanum Graveolens Extract
TonicAllantoin
Skin Conditioning
Adenosine
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Bisabolol
Antioxidant
Polyquaternium-10
Xanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Sodium Bicarbonate
Abrasive
Sodium Hydroxide
BufferingAminomethyl Propanol
BufferingPhenoxyethanol
Preservative
Benzyl Alcohol
Perfuming
Water, Butylene Glycol, Glycolic Acid, Glycerin, Lactic Acid, Caprylic/Capric Triglyceride, Malic Acid, Tartaric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Ng, Salicylic Acid, Glycyrrhiza Glabra Root, Camellia Sinensis Leaf Extract, Punica Granatum Extract, Lycium Barbarum Fruit Extract, Vitis Vinifera Seed Extract, Sambucus Nigra Fruit Extract, Camellia Oleifera Leaf, Chamomilla Recutita Flower Extract, Peucedanum Graveolens Extract, Allantoin, Adenosine, Hydrogenated Lecithin, Bisabolol, Polyquaternium-10, Xanthan Gum, Carbomer, Polysorbate 20, Sodium Bicarbonate, Sodium Hydroxide, Aminomethyl Propanol, Phenoxyethanol, Benzyl Alcohol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
