Lifecell All-In-One Anti-Aging Treatment Versus Perricone MD High Potency Classics Face Finishing & Firming Tinted Moisturizer SPF 30
This anti-aging treatment is formulated around Avena Sativa Kernel Extract and Thioctic Acid to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging day moisturizer is formulated around Tetrahexyldecyl Ascorbate and Thioctic Acid to soften the look of wrinkles and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialAvena Sativa Kernel Extract
AbrasiveButyrospermum Parkii Butter
Skin ConditioningCetearyl Alcohol
EmollientSilica
AbrasiveTitanium Dioxide
Cosmetic ColorantGlycerin
Humectant2-Dimethylamino Ethanol
Cetearyl Glucoside
EmulsifyingSclerotium Gum
Emulsion StabilisingIron Oxides
Thioctic Acid
AntioxidantTetrahydrobisdemethoxydiferuloylmethane
AntioxidantSpilanthes Acmella Flower Extract
Skin ConditioningRetinol
Skin ConditioningMalus Domestica Fruit Cell Culture Extract
Skin ConditioningMagnesium Ascorbyl Phosphate
AntioxidantGlycine Soja Oil
EmollientMagnesium Carbonate Hydroxide
BufferingCaprylic/Capric Triglyceride
MaskingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPhenoxyethanol
PreservativeTribehenin
EmollientAcrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingCeramide Ns
Skin ConditioningEthylhexylglycerin
Skin ConditioningPalmitoyl Oligopeptide
CleansingPalmitoyl Tetrapeptide-7
Skin ConditioningRetinyl Palmitate
Skin ConditioningPEG-10 Rapeseed Sterol
CleansingHesperidin Methyl Chalcone
AntioxidantSteareth-20
CleansingPalmitoyl Tripeptide-5
Skin ConditioningAcetyl Hexapeptide-8
HumectantDipeptide-2
Skin ConditioningCholecalciferol
Ubiquinone
AntioxidantTocopherol
AntioxidantTocopheryl Acetate
AntioxidantSodium Hyaluronate
HumectantZea Mays Oil
EmulsifyingAscorbyl Palmitate
AntioxidantWater, C12-15 Alkyl Benzoate, Avena Sativa Kernel Extract, Butyrospermum Parkii Butter, Cetearyl Alcohol, Silica, Titanium Dioxide, Glycerin, 2-Dimethylamino Ethanol, Cetearyl Glucoside, Sclerotium Gum, Iron Oxides, Thioctic Acid, Tetrahydrobisdemethoxydiferuloylmethane, Spilanthes Acmella Flower Extract, Retinol, Malus Domestica Fruit Cell Culture Extract, Magnesium Ascorbyl Phosphate, Glycine Soja Oil, Magnesium Carbonate Hydroxide, Caprylic/Capric Triglyceride, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Tribehenin, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Ceramide Ns, Ethylhexylglycerin, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Retinyl Palmitate, PEG-10 Rapeseed Sterol, Hesperidin Methyl Chalcone, Steareth-20, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Dipeptide-2, Cholecalciferol, Ubiquinone, Tocopherol, Tocopheryl Acetate, Sodium Hyaluronate, Zea Mays Oil, Ascorbyl Palmitate
Titanium Dioxide 4.2%
Cosmetic ColorantWater
Skin ConditioningGlycerin
HumectantCyclopentasiloxane
EmollientDimethicone
EmollientPentylene Glycol
Skin ConditioningEthylhexyl Methoxycrylene
Skin ConditioningPolyester-8
Skin ConditioningPolyglyceryl-3 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingBenzyl Alcohol
PerfumingAluminum Hydroxide
EmollientStearic Acid
CleansingCI 77491
Cosmetic ColorantCI 77492
Cosmetic ColorantCI 77499
Cosmetic ColorantDiethylhexyl Syringylidenemalonate
Skin ProtectingHydrogenated Lecithin
EmulsifyingCI 77891
Cosmetic ColorantIsohexadecane
EmollientBisabolol
AntioxidantMica
Cosmetic ColorantTetrahexyldecyl Ascorbate
AntioxidantPhenoxyethanol
PreservativeSilica Dimethyl Silylate
EmollientPolyester-1
Polysilicone-11
Polysorbate 60
EmulsifyingCaprylic/Capric Triglyceride
MaskingSodium Benzoate
MaskingPotassium Sorbate
PreservativeParfum
MaskingXanthan Gum
EmulsifyingHydrogenated Phosphatidylcholine
EmulsifyingCitronellol
PerfumingThioctic Acid
AntioxidantGeraniol
PerfumingAstaxanthin
Skin ConditioningHydroxycitronellal
PerfumingButylphenyl Methylpropional
PerfumingTitanium Dioxide 4.2%, Water, Glycerin, Cyclopentasiloxane, Dimethicone, Pentylene Glycol, Ethylhexyl Methoxycrylene, Polyester-8, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Benzyl Alcohol, Aluminum Hydroxide, Stearic Acid, CI 77491, CI 77492, CI 77499, Diethylhexyl Syringylidenemalonate, Hydrogenated Lecithin, CI 77891, Isohexadecane, Bisabolol, Mica, Tetrahexyldecyl Ascorbate, Phenoxyethanol, Silica Dimethyl Silylate, Polyester-1, Polysilicone-11, Polysorbate 60, Caprylic/Capric Triglyceride, Sodium Benzoate, Potassium Sorbate, Parfum, Xanthan Gum, Hydrogenated Phosphatidylcholine, Citronellol, Thioctic Acid, Geraniol, Astaxanthin, Hydroxycitronellal, Butylphenyl Methylpropional
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolThioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.
Alpha Lipoic Acid can be naturally found in the mitochondria of every cell.
Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. The antioxidants in Alpha Lipoic Acid have been shown to fight damage from cigarette smoke.
Studies also show Alpha Lipoic Acid plays a role in wound healing.
Thioctic Acid will break down when exposed to sunlight.
Many foods contain thioctic acid, including tomato, brussel sprouts, spinach, and broccoli.
Learn more about Thioctic AcidTitanium Dioxide (TD) is a mineral UV filter widely used in sunscreens and cosmetics.
It's one of only two UV filters officially classified as "mineral" by regulatory agencies (the other being Zinc Oxide).
A really common myth is that mineral filters work by reflecting UV light off your skin like tiny mirrors.
They don't only do that; modern research shows TD protects mostly by absorbing UV radiation, the same way chemical filters do.
When researchers measured this, reflection accounted for only about 4-5% of the protection (and less than SPF 2 on its own). The other ~95% comes from absorption: the UV photons hit the particle and their energy gets soaked up by its semiconductor band gap rather than bouncing off.
So "reflects vs. absorbs" was never really the right way to split mineral from chemical filters.
TD gives broad-spectrum protection that's strongest in the UVB and UVA-2 range and weaker in the UVA-1 range. Its UVA protection isn't quite as strong as Zinc Oxide's which is why you'll often see the two paired together.
Together, they make a solid broad-spectrum system.
TD is a great pick for sensitive, acne-prone, or redness-prone skin because it's non-irritating and chemically inert. Regulatory reviews classify it as a non-sensitizer and mild-to-non-irritant.
It's also unlikely to cause the "eye sting" some chemical filters are known for.
The main trade-off is cosmetic; TD can leave a white cast and has a thicker texture. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid formulas (and harder to shade-match on deeper skin tones).
Formulators often use micronized or nano-sized TD to cut down on white case and improve spreadability. Smaller particles scatter less visible light so the formula looks less chalky while still filtering UV.
TD is almost always bundled with coatings like Alumina, Silica, Stearic Acid, or Dimethicone. These coatings do two important jobs:
TD can be used at up to 25% in a finished sunscreen; this is the regulatory ceiling in both the US and the EU.
In practice, the amount in any given product varies a lot depending on the target SPF and whether it's paired with other UV filters.
TD is one of the most heavily vetted sunscreen ingredients out there. It is approved as a UV filter in all major markets worldwide, including the US, EU, UK, Japan, Korea, China, Australia, and Canada.
The safety evidence is solid. There was an old worry that nano particles might absorb through skin into the body but multiple studies (including on damaged, sunburned, and UV-irradiated skin) have shown that TD stays on the surface and the layer of dead skin cells on top of everything else.
There's also no evidence of carcinogenicity, mutagenicity, or reproductive toxicity from dermal exposure of this ingredient.
For those who have seen the headline about a 2022 EU ban on TD, that was on TD as a food additive (a complete separate use from topical sunscreen).
There are ongoing questions about how nano-TD might affect marine ecosystems. As of now, there has been no conclusive evidence that any form of TD (or any other sunscreen filter) harms coral reefs or marine life.
The science is still developing and it's a space worth watching rather than packing over.
However, several destinations have reef-safety sunscreen rules that restrict certain chemical filters and steer visitors toward mineral, non-nano options. If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.
Learn more about Titanium DioxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water