Versus

Differin Adapalene Gel 0.1% Acne Treatment Versus SkinBetter Science AlphaRet Overnight Cream

Facial Treatment
Night Moisturizer
American Brand United States
American Brand United States

Updated on May 16, 2024

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, common allergens, oils or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
AlphaRet Overnight Cream

Water

Skin Conditioning

Sodium Glycolate

Buffering

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Pentylene Glycol

Skin Conditioning

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

3,519 Routines
7% use in am
93% use in pm
69% use every day
When to use See routines that use it ->
115 Routines
1% use in am
99% use in pm
83% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.7 /5
from 35 ratings
Works Well (17) Absorbs Well (16) No Scent (15)
christychen's avatar

Christy C

24 days ago
Review

Honestly I was skeptical because it took my skin the FULL 12+ weeks to adjust to this. It was my first time using a retinoid and the purging was rough, but genuinely I’ve never seen my skin look so good after the purging ended. It absorbs well and a little goes a long way. I had to stop using it because I got too crazy with actives and I messed up my skin barrier super bad, but I’m hoping I can go Show more

#great value
#light
#absorbs well
#no scent
jazzzzz1's avatar

jazzzzz1

1 year ago
Review

I've been using this on and off for around 2 years. I thought this was going to help my acne, but looking back at pictures I actually think it's made my acne worse! It's made my acne areas really inflamed and red with angry spots. Think it's time to cut it out of my routine... Given it 2 stars as it soaks in pretty fast and is hydrating.

#irritating
#light
#absorbs well
#no scent

SkinBetter Science AlphaRet Overnight Cream 52 ingredients

3.3 /5
from 3 ratings
Expensive (3) Absorbs Well (2) Light (2)
carr0t's avatar

Caroline Strahan

9 months ago
Review

This is a great - albeit extremely expensive - alternative for people whose skin is too sensitive for tretonoin/retinols or who aren’t able to manage the dryness they can cause.

I’ve been using it for about a month and a half and I truly have noticed a huge difference in my pore size + fine lines. I do like to use a moisturizer afterwards just to be safe, but this could likely work as a Show more

#expensive
#light
#absorbs well
#no scent
beamayo's avatar

Bea Mayo

2 months ago
Review

Truly my holy grail product. It’s certainly pricey but it’s one of two expensive products I have in my routine and it’s worth the investment imo. One fl oz bottle lasts me ~3 months with nightly use. I’ve used this product consistently for 5 months now and have noticed my skin is brighter, more hydrated, and even toned. I was previously using .05% tret and my skin could never really handle it. Show more

#expensive
#light
#absorbs well
#no scent