Curology Custom Formula (Tretinoid 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%) Versus Dermatica Custom Formula (Tretinoin 0.015% And Niacinimide Lotion)
Updated on February 05, 2024
Overview
What they are
These products are both reef safe prescription. They have a total of 14 ingredients in common
Cool Features
They both contain retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Curology Custom Formula (Tretinoid 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%) 31 ingredients
Dermatica Custom Formula (Tretinoin 0.015% And Niacinimide Lotion) 28 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Curology Custom Formula (Tretinoid 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%) 31 ingredients
Dermatica Custom Formula (Tretinoin 0.015% And Niacinimide Lotion) 28 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Tretinoin 0.09%
Skin Conditioning
Clindamycin Phosphate 1%
Azelaic Acid 5%
Buffering
Aloe Barbadensis Leaf Juice
Skin Conditioning
C13-14 Isoparaffin
Emollient
Caprylic/Capric Triglyceride
MaskingWater
Skin ConditioningLaureth-7
EmulsifyingPhenoxyethanol
Preservative
Polyacrylamide
Tocopheryl Acetate
Antioxidant
Triethylene Glycol
Masking
Cetearyl Alcohol
Emollient
Polysorbate 60
Emulsifying
Isohexadecane
EmollientIsododecane
EmollientC13-15 Alkane
SolventGlyceryl Stearate
Emollient
PEG-75 Stearate
Polyacrylate-13
Polyisobutene
Polysorbate 20
Emulsifying
Polyurethane-39
Stearyl Behenate
Emollient
Cetyl Alcohol
Emollient
Ascorbic Acid
Antioxidant
Sodium Bisulfite
Antioxidant
Benzoic Acid 0.09%
Masking
Sorbic Acid 0.09%
Preservative
BHT
Antioxidant
Propanediol
SolventTretinoin 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%, Aloe Barbadensis Leaf Juice, C13-14 Isoparaffin, Caprylic/Capric Triglyceride, Water, Laureth-7, Phenoxyethanol, Polyacrylamide, Tocopheryl Acetate, Triethylene Glycol, Cetearyl Alcohol, Polysorbate 60, Isohexadecane, Isododecane, C13-15 Alkane, Glyceryl Stearate, PEG-75 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Stearyl Behenate, Cetyl Alcohol, Ascorbic Acid, Sodium Bisulfite, Benzoic Acid 0.09%, Sorbic Acid 0.09%, BHT, Propanediol
Tretinoin
Skin Conditioning
Niacinamide 4%
Smoothing
Water
Skin ConditioningPropylene Glycol
Humectant
Glycerin
Humectant
Panthenol
Skin Conditioning
Cetyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Isohexadecane
EmollientIsododecane
EmollientC13-15 Alkane
SolventDimethicone
Emollient
Propanediol
SolventPolyacrylate-13
Polyisobutene
Polysorbate 20
Emulsifying
Polyurethane-39
Phenoxyethanol 0.6%
Preservative
Tocopheryl Acetate
Antioxidant
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Ceramide NP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Cholesterol
Emollient
Sodium Lauroyl Lactylate
EmulsifyingXanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingSodium Hyaluronate
Humectant
Tretinoin, Niacinamide 4%, Water, Propylene Glycol, Glycerin, Panthenol, Cetyl Alcohol, Glyceryl Stearate, Isohexadecane, Isododecane, C13-15 Alkane, Dimethicone, Propanediol, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Phenoxyethanol 0.6%, Tocopheryl Acetate, Ceramide AP, Ceramide EOP, Ceramide NP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Xanthan Gum, Carbomer, Sodium Hyaluronate
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.
All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.
This is why tretinoin is so effective; it gets to work immediately on the skin.
Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.
Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.
It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Read about a form of retinoid you can purchase at the store, retinol.
Learn more about TretinoinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateIsohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.
Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.
Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.
Learn more about IsohexadecaneIsododecane is a fragrance, emollient, and solvent.
As an emollient, it helps your skin stay soft and hydrated. Emollients help trap moisture into your skin.
Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.
Isododecane is not absorbed into skin.
Learn more about IsododecaneC13-15 Alkane is a group of alkanes with 13 to 15 carbon atoms in the alkyl chain.
It is a solvent and texture enhancer. Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
Glyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePolyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.
Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers
Learn more about Polyacrylate-13Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobutenePolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20We don't have a description for Polyurethane-39 yet.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolIngredient Ratings
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