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Curology Custom Formula (Tretinoid 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%) Ingredients Explained

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Published on April 29, 2023 Submitted by JonsTheJonsIsBackOffical_143

Overview

What it is

Prescription with 31 ingredients that contains retinoid, Vitamin C and Vitamin E

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

Fun facts

Curology is from United States. This product is used in 2 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

You should know

Here's our breakdown of the notable ingredients, benefits, and concerns we determined from the ingredients in this product. Click any item to learn more.

Notable Ingredients

Retinoid
Vitamin C
Vitamin E

Benefits

Redness Reducing (3)
Reduces Irritation
Skin Texture
Reduces Large Pores
Anti-Aging (2)
Dark Spots (2)
Scar Healing (2)
Acne Fighting (2)
Brightening (3)

Concerns

May Worsen Oily Skin (2)
Acne Trigger
Irritating
Rosacea
Eczema (2)

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

Ingredients Overview

Here's our quick-to-read summary of the ingredients in this product. Keep scrolling if you'd like to learn more about what each ingredient does!
Ingredient
Features
1
Retinoid IconMay cause irritation IconHelps with Anti-Aging IconHelps fight Acne IconMay worsen Rosacea IconHelps brighten skin Icon
2
3
Buffering, Masking
Helps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon
4
Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
5
Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
6
Masking, Skin Conditioning
7
Skin Conditioning, Solvent
8
Emulsifying
9
Preservative
Preservative Icon
10
11
Antioxidant, Skin Conditioning
0 / 0
Vitamin E IconAntioxidant IconHelps brighten skin Icon
12
Masking, Perfuming
Fragrance Icon
13
Emollient, Emulsifying, Emulsion Stabilising
2 / 1
Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
14
Emulsifying
Not safe for Fungal Acne Icon
15
Emollient, Skin Conditioning, Solvent
16
Emollient, Solvent
17
Solvent
18
Emollient, Emulsifying
1 / 0
Not safe for Fungal Acne Icon
19
Not safe for Fungal Acne Icon
20
21
22
Emulsifying
0 / 0
Not safe for Fungal Acne Icon
23
24
Emollient, Skin Conditioning
Not safe for Fungal Acne Icon
25
Emollient, Emulsifying, Emulsion Stabilising, Masking
2 / 2
Fatty Alcohol Icon
26
Antioxidant, Buffering, Masking, Skin Conditioning
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
27
Antioxidant, Preservative
Antioxidant IconPreservative Icon
28
Masking, Preservative
Preservative IconMay worsen Eczema Icon
29
Preservative
Preservative IconMay worsen Eczema Icon
30
Antioxidant, Masking
Antioxidant Icon
31
Solvent

Ingredients Explained

This product contains 31 ingredients. Click on any ingredient to learn more about it
1
What it does:
Community Rating: Loved

Tretinoin is a form of Vitamin A. It is stronger than retinol and only available with a prescription in many countries.

Research on tretinoin has found it to be effective in anti-aging the skin. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles.

Tretinoin has also been found to be an effective acne treatment by reducing sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster. Due to its strength, it can cause irritation, redness, and dry skin. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about Retinol

Learn more about Tretinoin
2
What it does:
Community Rating: Loved

Clindamycin Phosphate is a perscription ingredient used to treat acne.

3
What it does: Buffering, Masking
Community Rating: Loved

Azelaic acid is a naturally occurring acid that is derived from grains. However, the lab-created form is typically used within cosmetic products as it has better shelf-stability.

It has been shown to be effective in the treatment of acne, rosacea, and other skin conditions. Azelaic acid helps reduce the growth of bacteria that cause acne and helps to reduce inflammation.

It also helps to improve the appearance of skin by reducing the production of sebum and unclogging pores.

Azelaic Acid also has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people. It is also non-comedogenic, meaning that it will not clog pores.

Learn more about Azelaic Acid
4
What it does: Skin Conditioning
Community Rating: Liked

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.

Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.

It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

Learn more about Aloe Barbadensis Leaf Juice
5
What it does: Emollient, Solvent
Community Rating: Very Disliked

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.

C13-14 Isoparaffin may not be fungal-acne safe.

Learn more about C13-14 Isoparaffin
6
What it does: Masking, Skin Conditioning
Community Rating: Mixed

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
7
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
8
What it does: Emulsifying
Community Rating: Very Disliked

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Laureth-7 is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

9
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

10
What it does:
Community Rating: Disliked

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Learn more about Polyacrylamide
11
What it does: Antioxidant, Skin Conditioning
Community Rating: Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
12
What it does: Masking, Perfuming

Triethylene Glycol is a fragrance.

13
What it does: Emollient, Emulsifying, Emulsion Stabilising
Community Rating: Very Disliked

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol
14
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.

In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.

Polysorbates are commonly used in medicine and foods.

Learn more about Polysorbate 60
15
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Mixed

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Learn more about Isohexadecane
16
What it does: Emollient, Solvent
Community Rating: Disliked

Isododecane is a fragrance, emollient, and solvent.

As an emollient, it helps your skin stay soft and hydrated. Emollients help trap moisture into your skin.

Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.

Isododecane is not absorbed into skin.

Learn more about Isododecane
17
What it does: Solvent

C13-15 Alkane is a group of alkanes with 13 to 15 carbon atoms in the alkyl chain.

It is a solvent and texture enhancer. Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.

18
What it does: Emollient, Emulsifying
Community Rating: Disliked

Glyceryl Stearate is a mix of glycerin and stearic acid.

Glyceryl Stearate is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced. The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
19
What it does:

Peg-75 Stearate isn't fungal acne safe.

20
What it does:

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.

Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers

Learn more about Polyacrylate-13
21
What it does:
Community Rating: Very Disliked

Polyisobutene is a synthetic polymer made from isobutene.

It is a film-forming agent and helps bind ingredients together.

Polyisobutene is not absorbed by the skin.

Learn more about Polyisobutene
22
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
23
What it does:

We don't have a description for Polyurethane-39.

24
What it does: Emollient, Skin Conditioning

Stearyl Behenate isn't fungal acne safe.

25
What it does: Emollient, Emulsifying, Emulsion Stabilising, Masking
Community Rating: Very Disliked

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Cetyl Alcohol is not related to SD alcohol, denatured alcohol, or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

26
What it does: Antioxidant, Buffering, Masking, Skin Conditioning
Community Rating: Loved

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
27
What it does: Antioxidant, Preservative

Sodium Bisulfite is an antioxidant and is a preservative.

28
What it does: Masking, Preservative
Community Rating: Disliked

Benzoic Acid is used to preserve and adjust the pH of products.

The antimicrobial property of Benzoic Acid helps elongate a product's shelf life. Its main role is to reduce fungi growth and is not found to be effective at fighting bacteria. Therefore Benzoic Acid is always added along with other preservatives.

In its pure form, Benzoic Acid looks like a white crystalline solid. It has slight solubility in water.

The name of Benzoic Acid comes from gum benzoin, which used to be the sole source of deriving this ingredient. Benzoic Acid is the most simple aromatic carboxylic acid.

Benzoic Acid is naturally occuring in strawberries, mustard, cinnamon, and cloves. It has a slight scent but is not considered to be a fragrance.

Learn more about Benzoic Acid
29
What it does: Preservative
Community Rating: Very Disliked

Sorbic Acid is a preservative. It is the most commonly used food preservative in the world.

Sorbic Acid is a natural antibiotic and highly effective at preventing the growth of fungus. It is less effective against bacteria.

Potassium Sorbate, another commonly-used preservative, is the potassium salt of Sorbic Acid.

Sorbic Acid may worsen eczema. We recommend speaking with a professional if you have any concerns.

Potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

Learn more about Sorbic Acid
30
What it does: Antioxidant, Masking
Community Rating: Very Disliked

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

BHT also helps stabilize products and prevent them from degrading. Many products are sensitive to air and light. BHT prevents them from breaking down when exposed.

31
What it does: Solvent
Community Rating: Liked

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Propanediol is not likely to cause sensitivity and considered safe to use.

It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Embed Ingredients

Here's what our community thinks of the 31 ingredients in this product ✨

26% are loved or liked
6% have mixed ratings
45% are disliked or very disliked
23% have no rating yet

When to use

Here's some more info on how this product is used by our community.

Directions

Apply product as prescribed by a professional.

Apply product as prescribed by a professional.

When to use

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Verified by SkinSort

We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.

The data we've presented on this page has been verified by a member of the SkinSort Team.

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Compared With

Here are some products that Curology Custom Formula (Tretinoid 0.09%, Clindamycin Phosphate 1%, Azelaic Acid 5%) is often compared with.

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