ZO Skin Health 10% Vitamin C Self-Activating Versus SkinBetter Science AlphaRet Overnight Cream
Updated on August 28, 2023
Overview
What they are
These products are both reef safe . They have a total of 7 ingredients in common
Cool Features
They both contain Vitamin C and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ZO Skin Health 10% Vitamin C Self-Activating 12 ingredients
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
ZO Skin Health 10% Vitamin C Self-Activating 12 ingredients
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningSodium Glycolate
BufferingGlycolic Acid
Buffering
Cetearyl Olivate
Pentylene Glycol
Skin ConditioningCyclopentasiloxane
Emollient
Isohexadecane
EmollientSorbitan Olivate
Emulsifying
Tetrahexyldecyl Ascorbate
Antioxidant
Glycerin
Humectant
Ceresin
Emulsion StabilisingGlycol Palmitate
Emulsifying
Butylene Glycol
Humectant
Niacinamide
Smoothing
Squalane
Emollient
Methyl Gluceth-20
HumectantEthyl Lactyl Retinoate
Abrasive
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide NP
Skin Conditioning
Hyaluronic Acid
Humectant
Ubiquinone
Antioxidant
Tocopherol
Antioxidant
Bisabolol
Masking
Tocopheryl Acetate
Antioxidant
Superoxide Dismutase
Antioxidant
Butyrospermum Parkii Butter
Skin Conditioning
Allantoin Glycyrrhetinic Acid
Skin ProtectingSodium PCA
HumectantPanthenol
Skin Conditioning
Camellia Sinensis Leaf Extract
Antimicrobial
Portulaca Oleracea Extract
Skin ConditioningLinoleic Acid
Cleansing
Cholesterol
Emollient
Linolenic Acid
Cleansing
Magnesium Aluminum Silicate
AbsorbentDimethyl Isosorbide
SolventDimethicone
Emollient
Glyceryl Stearate
Emollient
PEG-100 Stearate
Steareth-2
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingAcacia Senegal Gum
MaskingXanthan Gum
EmulsifyingHydrated Silica
Abrasive
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Tromethamine
BufferingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
CI 77891
Cosmetic ColorantWater, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii Butter, Allantoin Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, CI 77891
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneTetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinonePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
ZO Skin Health 10% Vitamin C Self-Activating 12 ingredients
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
Reviews
Here's what our community thinks
ZO Skin Health 10% Vitamin C Self-Activating 12 ingredients
SkinBetter Science AlphaRet Overnight Cream 52 ingredients
This is a great - albeit extremely expensive - alternative for people whose skin is too sensitive for tretonoin/retinols or who aren’t able to manage the dryness they can cause.
I’ve been using it for about a month and a half and I truly have noticed a huge difference in my pore size + fine lines. I do like to use a moisturizer afterwards just to be safe, but this could likely work as a Show more
Truly my holy grail product. It’s certainly pricey but it’s one of two expensive products I have in my routine and it’s worth the investment imo. One fl oz bottle lasts me ~3 months with nightly use. I’ve used this product consistently for 5 months now and have noticed my skin is brighter, more hydrated, and even toned. I was previously using .05% tret and my skin could never really handle it. Show more
