Versus

Synergie Skin Dermiotic Pre-Serum Elixir Versus SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule

Essence
Ampoule
Australian Brand Australia
Korean Brand South Korea

Updated on January 15, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 5 ingredients in common

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Ingredients Side-by-side

found in both products
Madagascar Centella Probio-Cica Intensive Ampoule

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Water

Skin Conditioning

Propanediol

Solvent

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Learn more about Betaine
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

When to use

5 Routines
60% use in am
40% use in pm
100% use every day
930 Routines
37% use in am
63% use in pm
90% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Synergie Skin Dermiotic Pre-Serum Elixir 20 ingredients

Dermiotic Pre-Serum Elixir hasn't been rated yet.
Rate it now

SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule 44 ingredients

4.2 /5
from 17 ratings
Works Well (13) Hydrating (11) Great Value (9)
Cheeks's avatar

Cheeks

4 months ago
Review

This has been my favourite barrier supporting ampoule/serum to date! My skin soaks this up I use this both am and pm (with a little more in the pm). I have dry, sensitive and rosacea prone skin and this hasn’t ever aggravated anything, no reactions, blends effortlessly and just gives me a hydrated glowy look! Love it! It’s a creamy ampoule but not super thick and just melts into the skin. It’s so Show more

#great value
#hydrating
#light
#absorbs well
m.evstigneev's avatar

M. Evstigneev

4 months ago
Review

Lovely texture and a good value. Unfortunately, my skin reacted violently to it, it was very irritating, especially around my cheekbones. It is ironic because it’s marketed as soothing and calming for sensitive skin, and I’m not even that sensitive. My suspicion is that I can’t tolerate fermented ingredients because it happened with some other fermented products as well.

#great value
#irritating
#light
#no scent