Versus

Skintific Retinol Pro+ Advanced Renew Regenerating Moisturizer Versus Dr. Althea 345 Relief Cream

Night Moisturizer
General Moisturizer
Chinese Brand China
Korean Brand South Korea

Updated on April 29, 2025

Overview

What they are

These products are both cruelty-free . They have a total of 10 ingredients in common

Cool Features

They both contain hyaluronic acid, niacinamide, peptides and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol Pro+ Advanced Renew Regenerating Moisturizer

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Pentylene Glycol

Skin Conditioning

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Isononyl Isononanoate

Emollient

C12-20 Acid PEG-8 Ester

Emulsifying
Not safe for Fungal Acne Icon

Nylon-12

Non-Reef-Safe Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

1,2-Hexanediol

Skin Conditioning

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Hydroxyacetophenone

Antioxidant
Antioxidant Icon

Hydroxyethylpiperazine Ethane Sulfonic Acid

Buffering

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Emulsion Stabilising

Sodium Polyacryloyldimethyl Taurate

Emulsion Stabilising

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Hydroxydecyl Ubiquinone

Antioxidant
Antioxidant Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Potassium Cetyl Phosphate

Emulsifying

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Hydrogenated Polydecene

Emollient

Sophora Flavescens Root Extract

Antioxidant
Antioxidant Icon

Coco-Glucoside

Cleansing

Hydroxypropyl Cyclodextrin

Masking

Tribulus Terrestris Fruit Extract

Skin Conditioning

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Dipropylene Glycol

Masking

Cornus Officinalis Fruit Extract

Skin Conditioning

Fullerenes

Antimicrobial

Copper Tripeptide-1

Skin Conditioning
Peptide IconGood for Skin Texture IconHelps with Anti-Aging Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning

Pinus Densiflora Leaf Extract

Antimicrobial
Antioxidant Icon

Disodium EDTA

Trideceth-10

Cleansing

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Lactobacillus Ferment

Skin Conditioning

BHT

Antioxidant
Antioxidant Icon

Quaternium-73

BHA

Antioxidant
Antioxidant Icon

Tetrapeptide-4

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-8

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Phytol

Emollient
Fragrance Icon

Arginine/Lysine Polypeptide

Skin Conditioning
Peptide Icon

Pvp

Emulsion Stabilising
0 / 0
345 Relief Cream

Water

Skin Conditioning

Propanediol

Solvent

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Cyclohexasiloxane

Emollient
Silicon Icon

1,2-Hexanediol

Skin Conditioning

Caprylic/Capric Triglyceride

Masking

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Polyglycerin-3

Humectant

Polyglyceryl-10 Stearate

Skin Conditioning
Not safe for Fungal Acne Icon

Hydrogenated Poly(C6-14 Olefin)

Emollient

Hydrogenated Polydecene

Emollient

Laminaria Japonica Extract

Skin Protecting

Eclipta Prostrata Leaf Extract

Skin Conditioning

Melia Azadirachta Flower Extract

Skin Conditioning

Houttuynia Cordata Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Oenothera Biennis Flower Extract

Astringent

Curcuma Longa Root Extract

Masking
Fragrance Icon

Ocimum Sanctum Leaf Extract

Skin Conditioning

Calendula Officinalis Flower Extract

Masking
Fragrance IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Agave Tequilana Leaf Extract

Astringent

Sargassum Fulvellum Extract

Skin Conditioning

Corallina Officinalis Extract

Skin Conditioning

Lavandula Angustifolia Flower Extract

Cleansing
May cause irritation IconEU Allergen Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Opuntia Ficus-Indica Stem Extract

Skin Conditioning

Gardenia Florida Fruit Extract

Skin Conditioning

Perilla Ocymoides Leaf Extract

Tonic

Hibiscus Sabdariffa Flower Extract

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Hydrogenated Lecithin

Emulsifying

Empetrum Nigrum Fruit Juice

Skin Conditioning

Dicaprylyl Carbonate

Emollient

C14-22 Alcohols

Emulsion Stabilising

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polymethylsilsesquioxane

Silicon Icon

Dipropylene Glycol

Masking

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

C12-20 Alkyl Glucoside

Emulsifying

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Ethylhexylglycerin

Skin Conditioning

Polyquaternium-51

Skin Conditioning

Tromethamine

Buffering

Fructooligosaccharides

Humectant

Adenosine

Skin Conditioning
Good for Minimizing Pores IconGood for Scar Healing Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Glycine Soja Sterols

Emollient
0 / 0 Not safe for Fungal Acne Icon

PEG-40 Castor Oil

Emulsifying
0 / 0 Oil IconNot safe for Fungal Acne Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Resveratrol

Antioxidant
Antioxidant IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Oligopeptide-1

Skin Conditioning
Peptide Icon

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Emollient, Masking, Skin Conditioning

Hydrogenated Polydecene is an emollient. It creates a non-occlusive film on the skin that offers extra protection for your skin barrier.

The texture of Hydrogenated Polydecene ranges from light and silky to rich.

Hydrogenated Polydecene is the end compound of controlled hydrogenation of Polydecene.

Learn more about Hydrogenated Polydecene
Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

When to use

147 Routines
47% use in am
53% use in pm
95% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Skintific Retinol Pro+ Advanced Renew Regenerating Moisturizer 48 ingredients

Retinol Pro+ Advanced Renew Regenerating Moisturizer hasn't been rated yet.
Rate it now

Dr. Althea 345 Relief Cream 56 ingredients

2.6 /5
from 5 ratings
Hydrating (3) Broke Me Out (3) Absorbs Well (2)
sila3's avatar

Sila

2 months ago
Review

I really like how well it moisturizers my skin, but it’s not even worth the hype at all its like the Tirtir Cushion overhyped. There are definitely better moisturizers out there it broke me out so i wouldn’t recommend😐.

#broke me out
#absorbs well
glittertimes's avatar

Ryan 🩷

2 months ago
Review

The hype on this moisturizer is real! This is amazing!!! It's hydrating, absorbs well, and the ingredients have already made my acne scars begin to fade. The 3-in-1 nature moisturizes, helps with blemishes, and soothes irritation and sensitivity.

PROS:
-Hydrates extremely well
-Reduces appearance of acne scars
-Moisturization LASTS
-Non irritating (great for sensitive skin!!)
-Non oily Show more

#expensive
#hydrating
#light
#absorbs well