Purcell L-Glutathione Flexible Liposome Versus Numbuzin No.5 Vitamin Concentrated Serum
Updated on April 08, 2025
Overview
What they are
These products are both reef safe serums. They have a total of 13 ingredients in common
Cool Features
They both contain niacinamide and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Purcell L-Glutathione Flexible Liposome 21 ingredients
Numbuzin No.5 Vitamin Concentrated Serum 47 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Purcell L-Glutathione Flexible Liposome 21 ingredients
Numbuzin No.5 Vitamin Concentrated Serum 47 ingredients
Key Ingredients
Benefits
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
As an antioxidant, it prevents oxidative damage to parts of our cell.
While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.
This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.
Learn more about Glutathione1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Niacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideTranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.
Once applied, Tranexamic Acid starts decreasing inflammation from UV exposure. Tranexamic Acid also prevents our skin cells from meeting the pigment production cells.
Its brightening property makes it great at reducing the appearance of acne scars and marks.
Fun fact: Tranexamic Acid is also a medication used to reduce heavy bleeding.
This acid is derived from lysine, an amino acid.
Learn more about Tranexamic AcidTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Dipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Purcell L-Glutathione Flexible Liposome 21 ingredients
Numbuzin No.5 Vitamin Concentrated Serum 47 ingredients

Reviews
Here's what our community thinks
Purcell L-Glutathione Flexible Liposome 21 ingredients
Numbuzin No.5 Vitamin Concentrated Serum 47 ingredients
This serum is one of the best all-round anti-oxidant and dark spot serums containing:
- vitamin c
- Glutathion!!
- 5% niacinamide
- Q10
- Alpha Arbutin
(Unfortunately they removed TXA)
Skin type: combi acne prone
This is not just a dark spot serum, its a perfect anti-oxidant serum in the morning. Glutathion is a killer ingredient and the concentration of Vit C is low.
My acne Show more
This is an okay serum for brightening. I have dry, eczema and rosacea skin and didn’t have any issues with breakouts or irritation BUT I didn’t see any big improvement either and used for about 3 months. I found that it left a slightly tacky feeling no matter how long I left between steps in my routine. No smells or fragrances so that was also a plus.