This brightening serum is formulated around Niacinamide and Tranexamic Acid to fade the look of dark spots and brighten dull-looking skin.
This anti-aging serum is formulated around Tetrahexyldecyl Ascorbate and Palmitoyl Tripeptide-5 to soften the look of wrinkles and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Vaccinium Vitis-Idaea Fruit Extract
Antioxidant
Butylene Glycol
Humectant
Niacinamide
Smoothing
Panthenol
Skin Conditioning
Tranexamic Acid
Astringent
Water
Skin Conditioning1,2-Hexanediol
Skin Conditioning
Neopentyl Glycol Dicaprate
EmollientCaprylic/Capric Triglyceride
Masking
Sorbitol
Humectant
Bifida Ferment Lysate
Skin Conditioning
Chondrus Crispus Extract
Skin Conditioning
Butyrospermum Parkii Butter
Skin Conditioning
Saccharum Officinarum Extract
MoisturisingAlpha-Arbutin
Antioxidant
Sodium Hyaluronate
Humectant
Melia Azadirachta Flower Extract
Skin ConditioningOcimum Sanctum Leaf Extract
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningCurcuma Longa Root Extract
Antioxidant
Corallina Officinalis Extract
Skin Conditioning
Tremella Fuciformis Extract
Humectant
Pentylene Glycol
Skin Conditioning
Glycerin
Humectant
3-O-Ethyl Ascorbic Acid
Skin Conditioning
Bisabolol
Antioxidant
Tromethamine
BufferingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Allantoin
Skin Conditioning
Glutathione
Ceramide NP
Skin Conditioning
Beta-Glucan
Skin Conditioning
Dipotassium Glycyrrhizate
Humectant
Tocopherol
Antioxidant
Ascorbic Acid
Antioxidant
Ascorbyl Glucoside
Antioxidant
Tocopheryl Acetate
Antioxidant
Hydroxypropyl Cyclodextrin
MaskingUbiquinone
Antioxidant
Thioctic Acid
Antioxidant
Potassium Hydroxide
BufferingBehenyl Alcohol
Emollient
Carbomer
Emulsion StabilisingXanthan Gum
EmulsifyingDisodium EDTA
ChelatingVaccinium Vitis-Idaea Fruit Extract, Butylene Glycol, Niacinamide, Panthenol, Tranexamic Acid, Water, 1,2-Hexanediol, Neopentyl Glycol Dicaprate, Caprylic/Capric Triglyceride, Sorbitol, Bifida Ferment Lysate, Chondrus Crispus Extract, Butyrospermum Parkii Butter, Saccharum Officinarum Extract, Alpha-Arbutin, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Tremella Fuciformis Extract, Pentylene Glycol, Glycerin, 3-O-Ethyl Ascorbic Acid, Bisabolol, Tromethamine, Ethylhexylglycerin, Adenosine, Hydrogenated Lecithin, Allantoin, Glutathione, Ceramide NP, Beta-Glucan, Dipotassium Glycyrrhizate, Tocopherol, Ascorbic Acid, Ascorbyl Glucoside, Tocopheryl Acetate, Hydroxypropyl Cyclodextrin, Ubiquinone, Thioctic Acid, Potassium Hydroxide, Behenyl Alcohol, Carbomer, Xanthan Gum, Disodium EDTA
Cyclopentasiloxane
Emollient
Dimethicone
Emollient
Tetrahexyldecyl Ascorbate
Antioxidant
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide NP
Skin Conditioning
Tocotrienols
Skin Conditioning
Tocopherol
Antioxidant
Ubiquinone
Antioxidant
Thioctic Acid
Antioxidant
Tocopheryl Acetate
Antioxidant
Magnesium Ascorbyl Phosphate
Antioxidant
Ferulic Acid
Antimicrobial
Beta-Glucan
Skin Conditioning
Superoxide Dismutase
Antioxidant
Epigallocatechin Gallate
Antioxidant
Ergothioneine
Antioxidant
Glutathione
Xanthophylls
Skin ConditioningGlycine Soja Seed Extract
Skin Conditioning
Glycerin
Humectant
Arctostaphylos Uva Ursi Leaf Extract
Skin Conditioning
Lupinus Albus Seed Extract
Skin ConditioningCurcuma Longa Root
Skin ConditioningElaeis Guineensis Oil
Emollient
Phenoxyethanol
Preservative
Cyclopentasiloxane, Dimethicone, Tetrahexyldecyl Ascorbate, Palmitoyl Tripeptide-5, Ceramide NP, Tocotrienols, Tocopherol, Ubiquinone, Thioctic Acid, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Ferulic Acid, Beta-Glucan, Superoxide Dismutase, Epigallocatechin Gallate, Ergothioneine, Glutathione, Xanthophylls, Glycine Soja Seed Extract, Glycerin, Arctostaphylos Uva Ursi Leaf Extract, Lupinus Albus Seed Extract, Curcuma Longa Root, Elaeis Guineensis Oil, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Beta-Glucan is a soluble polysaccharide (a chain of glucose sugars) sourced from the cells walls of oats, baker's yeast, mushrooms, and seaweed.
It's a rare ingredient that pulls double-duty as a heavy-duty hydrator and skin-soothing repair agent.
On the surface, it acts as a humectant that holds water in place and reduces moisture loss for a plumper, smoother feel, while its anti-inflammatory and antioxidant properties make it a great pick for calming redness or sensitive skin
The more interesting story is underneath:
Despite its large molecular size, oat beta-glucan has been shown to penetrate the epidermis and reach the dermis by slipping between skin cells. Here, it interacts with fibroblasts and macrophages to nudge collagen synthesis and support wound repair.
A small 2005 split-face clinical study of 27 subjects found topical beta-glucan produced measurable reductions in wrinkle depth, height, and roughness after 8 weeks of use.
It is worth noting the trial was small and the penetration testing used frozen, irradiated skin so the anti-aging data is encouraging rather than definitive.
This ingredient gets along with pretty much everything and is typically used around 0.1-1%.
Fungal acne: This ingredient is not a food source for the Malassezia yeast because it is a glucose polysaccharide with no fatty acid or ester component.
Learn more about Beta-GlucanCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPGlutathione is a tiny protein-like molecule (a "tripeptide" build from 3 amino acids: glycine, cysteine, and glutamic acid) that your body already makes on its own.
Inside your body, it acts as one of the skin's main antioxidants that help fight against free radicals.
In skincare, it's best known as a brightening ingredient that slows down tyrosinase, the key enzyme that makes skin pigment. It also nudges the skin toward making a lighter type of pigment instead of a darker one.
This is why you'll see it in products aimed at dark spots and uneven tone.
A small number of real human trials have found a topical glutathione lotion:
The honest caveat is that the current evidence is still thin (few studies, small groups, short timelines). Glutathione also doesn't absorb into skin very easily so results tend to be modest and fade if you stop using it.
One thing worth clearing up:
The scary side effects you may have heard about come from glutathione injected intravenously, which has real safety concerns. Applying it topically is a completely different thing and has a clean track record.
Most human studies used it around 2% (as Glutathione or Glutathione Disulfide) and a 2% oxidized glutathione lotion and a 2% S-acyl glutathione cream are the concentrations with actual clinical data behind them.
There's no established "ideal" percentage yet but 1-2% is the evidence-backed range.
Allergy-wise, there is very low risk for this ingredient; it was well-tolerated across the topical trials. Only one participant had mild temporary redness that cleared up on its own and another study reported no adverse reactions at all.
One trial had ~10% of users drop out for irritation was using a combination cream that also had 10% azelaic acid so the irritation likely wasn't from the glutathione. There's no notable contact-allergy signal for topical glutathione in the literature but patch-testing before first use is still sensible for those with sensitive skin.
Learn more about GlutathioneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.
Alpha Lipoic Acid can be naturally found in the mitochondria of every cell.
Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. The antioxidants in Alpha Lipoic Acid have been shown to fight damage from cigarette smoke.
Studies also show Alpha Lipoic Acid plays a role in wound healing.
Thioctic Acid will break down when exposed to sunlight.
Many foods contain thioctic acid, including tomato, brussel sprouts, spinach, and broccoli.
Learn more about Thioctic AcidTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about Ubiquinone
