Updated on June 26, 2024
Overview
What they are
These products are both reef safe serums. They have a total of 12 ingredients in common
Cool Features
They both contain hyaluronic acid, peptides and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils or parabens
What's Inside
They both contain sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
DRMTLGY Needle-Less Serum 29 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
At a glance
Click on any of the items below to learn more
DRMTLGY Needle-Less Serum 29 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
Notable Ingredients
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Benefits
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This product contains 16 ingredients that may have this attribute:
- Tripeptide-10 Citrulline
- Acetyl Octapeptide-3
- Palmitoyl Hexapeptide-12
- Acetyl Tetrapeptide-11
- Acetyl Hexapeptide-8
- Acetyl Hexapeptide-1
- Palmitoyl Oligopeptide
- Acetyl Tetrapeptide-9
- Acetyl Tetrapeptide-2
- Tripeptide-1
- Palmitoyl Tetrapeptide-7
- Hexapeptide-11
- Dipeptide Diaminobutyroyl Benzylamide Diacetate
- Palmitoyl Tripeptide-5
- Trifluoroacetyl Tripeptide-2
- Palmitoyl Tripeptide-1
Benefits
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Not safe for Fungal Acne
Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.
Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Isopropyl Myristate is an emollient, thickening agent, and texture enhancer. It is created from isopropyl alcohol and myristic acid.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Natto Gum is created by fermenting a soy protein using Bacillus natto (a bacteria). It is used as a texture enhancer.
Acetyl Octapeptide-3 is a synthetic peptide. It is often called a botox alternative due to its ability to restrict the movement of muscles, and thus reduce the appearance of fine-lines.
Not safe for Fungal Acne
Palmitoyl Hexapeptide-12 isn't fungal acne safe and is a peptide.
Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Not safe for Fungal Acne
Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.
Not safe for Fungal Acne
Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
7 Benefits 3 Concerns
Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.
Antioxidant 6 Benefits
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
This ingredient is a vegetable-derived protein made to mimic hydrolyzed collagen. It is created from soy, or glycine soja.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Pseudoalteromonas Ferment Extract isn't fungal acne safe.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.
Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. Leuconostoc comes from lactic acid. This bacteria is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.
We don't have a description for Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
Octyldodecanol is a fatty alcohol. It is primarily used to enhance the texture of products.
2 Concerns
Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Sodium Propoxyhydroxypropyl Thiosulfate Silica is a type of sulfate.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, Peg-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePalmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
Palmitoyl Tripeptide-1 is a signal peptide. This means it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetatePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
DRMTLGY Needle-Less Serum 29 ingredients
Peter Thomas Roth Peptide 21 Wrinkle Resist Serum 56 ingredients
Reviews
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