Dr. Denese SkinScience Triple Strength Wrinkle Smoother Advanced Treatment Ingredients Explained
Published on December 12, 2022
Overview
What it is
Facial treatment with 57 ingredients that contains AHA, hyaluronic acid, peptides and Vitamin E
Cool Features
It is cruelty-free
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, parabens or sulfates
Fun facts
Dr. Denese SkinScience is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
Ingredient List (57)
Water, Glycerin, Caprylic/Capric Triglyceride, Simmondsia Chinensis Seed Oil, Butylene Glycol, Glycereth-26, Squalane, Stearyl Olivate, Octyldodecyl Olivate, Di-C12-15 Alkyl Fumarate, Dimethicone, Stearic Acid, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide, Pantothenic Acid, Rhododendron Ferrugineum Leaf Cell Culture Extract, Globularia Cordifolia Callus Culture Extract, Foeniculum Vulgare Fruit Extract , Humulus Lupulus Extract, Melissa Officinalis Leaf Extract, Viscum Album Leaf Extract, Chamomilla Recutita Flower Extract, Achillea Millefolium Extract, Glycine Soja Sterols, Adenosine, Urea, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Coco-Glucoside, Mica, Titanium Dioxide, CI 77492, Lecithin, Sodium Benzoate, Lactic Acid, Polysorbate 60, Carbomer, Polysorbate 20, Polymethyl Methacrylate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrogenated Lecithin, Dimethiconol, Polyglyceryl-3 Diisostearate, Tocopheryl Acetate, Arginine, Citrus Paradisi Peel Extract, Hydroxypropyl Bislauramide Mea, Lactic Acid/Glycolic Acid Copolymer, Dextran, Disodium EDTA, Isomalt, Phenoxyethanol, Ethylhexylglycerin
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Ingredient Info
Alcohol Free
This product is free of harsh alcohols 🎉
Contains Silicon
Ingredients in this product that are types of silicon:
Contains Fragrance
Ingredients in this product that are forms of fragrance:
Sulfate Free
This product is free of sulfates 🎉
Paraben Free
This product is free of parabens 🎉
Contains Oils
Ingredients in this product that are types of oil:
Not Malassezia Safe
Ingredients in this product that are not malassezia safe:
Not Reef Safe
Ingredients in this product that are not reef safe:
EU Allergen Free
This product is free of EU allergens 🎉
Non Vegan
This product is not vegan 😥
Cruelty Free
This product is cruelty-free 🎉
Ingredients Overview
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCaprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideThis ingredient is the fixed oil extracted from seeds of the desert shrub Jojoba. It is more commonly known as jojoba oil. The seed oil is liquid wax ester from the plant. It is non-comedogenic.
Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient. Jojoba contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant. Antioxidants help protect your skin against free-radical damage. This may help in anti-aging.
Jojoba seed oil is a humectant, meaning it helps draw moisture from the air. This helps keep your skin hydrated.
While jojoba has antibacterial properties, it is only able to kill some bacteria. It has also been shown to help in wound healing. Indigenous cultures have used jojoba as a moisturizer and to help treat burns.
It is found to be similar to natural human skin sebum, so it has a great effect on dry skin. Jojoba oil may even help with regulating sebum production.
Although jojoba oil is non-comedogenic, we recommend speaking with a professional about using this ingredient if you have any concerns.
Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Jojoba is native to the southwestern US.
Learn more about Simmondsia Chinensis Seed OilButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneWe don't have a description for Di-C12-15 Alkyl Fumarate.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.
Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.
As an emollient, stearic acid helps soften skin. It aids the skin's protective barrier by preventing water loss. It also provides a gentle cleansing effect without stripping away natural oils.
Stearic acid may also be used to enhance the texture of products. It can add volume and stabilize ingredients such as water and oil. This can help water and oil ingredients from separating.
Sources of stearic acid include animal or vegetable fats/oils such as coconut or shea. It can be naturally found in butter, cocoa butter, shea butter, vegetable fats, and animal tallow.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about Stearic AcidPalmitoyl Tripeptide-38 isn't fungal acne safe and is a peptide.
Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
Palmitoyl Tripeptide-1 is a signal peptide. This means it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.
Due to the palmitic acid base, it may not be malassezia folliculitis safe.
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl OligopeptidePantothenic Acid is an essential vitamin. Our bodies use it for metabolizing fatty acids, proteins, carbohydrates, and fats.
We don't have a description for Rhododendron Ferrugineum Leaf Cell Culture Extract.
We don't have a description for Globularia Cordifolia Callus Culture Extract.
We don't have a description for Foeniculum Vulgare Fruit Extract.
We don't have a description for Humulus Lupulus Extract.
We don't have a description for Melissa Officinalis Leaf Extract.
We don't have a description for Viscum Album Leaf Extract.
Chamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractAchillea Millefolium Extract comes from the yarrow plant. Yarrow is rich in antioxidants and fatty acids.
Glycine Soja Sterols is derived from the soybean plant. Sterols are an organic compound and technically an alcohol.
Unlike solvent alcohols, glycine soja sterols have emollient properties and help hydrate the skin.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Sterols can be found in plants, animals, and fungi.
Learn more about Glycine Soja SterolsAdenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineUrea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.
Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.
In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.
Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.
Learn more about UreaAllantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWe don't have a description for Hydroxypropyl Cyclodextrin.
Coco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.
Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away. Coco-Glucoside is considered gentle and non-comedogenic.
This ingredient is a known skin-irritant.
Learn more about Coco-GlucosideMica refers to a group of silicate minerals. Mica crystals are easily split to give products a shimmer. These crystals are able to reflect light to temporarily give your skin a glowy look.
Mica is found to be safe. Trace amounts of heavy metals may be found in mica, but these metals are not harmful in our personal products.
Mica has been used since prehistoric times throughout the world. Ancient Egyptian, Indian, Greek, Roman, Aztec, and Chinese civilizations have used mica.
Mica can be naturally found throughout the world. However, some sources of mica may be controversial. In 2016, mica mined in the Jharkhand state in India was found to be using child labor. However, companies are able to source ethical mica affiliated with international organizations that monitor the mica supply chain.
Learn more about MicaTitanium dioxide is known for its UVA and UVB protection properties. It is non-comedogenic and non-irritating. Titanium Dioxide is a physical sunscreen. Physical sunscreens reflect light and prevent it from reaching your skin.
Protecting your skin against UV radiation can prevent the signs of aging. Sun damage is associated with fine-lines, wrinkles, loss of firmness, and hyperpigmentation. Titanium dioxide can help prevent premature aging.
With modern production, nano-scale or fine-grade titanium dioxide can be easily produced for cosmetics. In sunscreen, titanium dioxide absorbs UV light. Our skin is not able to absorb Titanium dioxide, even nanoparticles.
Titanium itself is the 9th most common element in the Earth's crust. Titanium dioxide is formed when oxygen is introduced and can be found in ores, dust, sand, and soil.
Pure titanium dioxide is a white powder that is used in many products to add or change color.
Learn more about Titanium DioxideCi 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77492Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Lecithin is an emollient. Emollients help soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.
Learn more about LecithinSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
Sodium Benzoate is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateLactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
Benefits of Lactic Acid are that it can help to reduce large pores and reduce the effects of aging. Some potential downsides are that it can be bad for dry skin, cause irritation, worsen eczema, and worsen rosacea.
Not only does it help exfoliate the skin, it helps strengthen the skin's barrier. When applied, lactic acid helps the skin create ceramides.
Lactic acid is an over-the-counter chemical exfoliant that comes from the fermentation of lactose — a carbohydrate found in milk.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20We don't have a description for Polymethyl Methacrylate.
This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Hydrogenated Lecithin is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within.
The phospholipids in Hydrogenated Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier to be better absorbed.
As an emulsifier, it prevents oil and water ingredients from separating.
Learn more about Hydrogenated LecithinDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Polyglyceryl-3 Diisostearate is an emulsifer and emollient. It comes from Isostearic Acid and Polyglycerin-3.
As an emulsifier, it helps stabilize products by preventing oils and water from separating.
This ingredient may not be Malassezia folliculitis, or fungal acne safe.
Learn more about Polyglyceryl-3 DiisostearateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateArginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineCitrus Paradisi Peel Extract is a fragrance.
We don't have a description for Hydroxypropyl Bislauramide Mea.
We don't have a description for Lactic Acid/Glycolic Acid Copolymer.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
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