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Sk-II R.N.A. POWER Anti-Aging Essence Serum Versus Lancôme Advanced Génifique Anti-Aging Face Serum

Serum
Serum
Japanese Brand Japan
French Brand France

Updated on June 26, 2024

Overview

What they are

These products are both serums. They have a total of 7 ingredients in common

Suited For

They're both likely to be good for dry skin, brightening skin and dark spots

Free From

They both do not contain any sulfates

What's Inside

They both contain harsh alcohols, common allergens, fragrances, oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
R.N.A. POWER Anti-Aging Essence Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Galactomyces Ferment Filtrate Humectant
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Galactomyces Ferment Filtrate (GFF) is a yeast traditionally used to make the Japanese alcoholic beverage, sake.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Phytosteryl/Octyldodecyl Lauroyl Glutamate Skin Conditioning

We don't have a description for Phytosteryl/Octyldodecyl Lauroyl Glutamate.

Unknown Full details ->
Isopropyl Isostearate Emollient, Skin Conditioning
4-5 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Isopropyl isodecanoate is a lipid created from isopropyl alcohol and isostearic acid.

4-5 Com. / 0 Irr.
Very Disliked Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Xylitol Humectant, Skin Conditioning

Xylitol is a humectant and prebiotic. It can help with dry skin.

Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer

We don't have a description for Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer.

Very Disliked Full details ->
Boron Nitride Absorbent, Skin Conditioning

Boron Nitride is compound consisting of boron and nitrogen. It is used to absorb oil and modify adherence/ slip in products.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Peg-20 Sorbitan Cocoate Emulsifying

We don't have a description for Peg-20 Sorbitan Cocoate.

Unknown Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Dimethicone/Vinyl Dimethicone Crosspolymer Skin Conditioning

Dimethicone/Vinyl Dimethicone Crosspolymer is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.

Very Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Dipentaerythrityl Tri-Polyhydroxystearate Emollient, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Dipentaerythrityl Tri-Polyhydroxystearate isn't fungal acne safe.

Unknown Full details ->
Peg-11 Methyl Ether Dimethicone Emulsifying, Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Peg-11 Methyl Ether Dimethicone is a type of silicone.

Unknown Full details ->
Aminomethyl Propanol Buffering

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Ceratonia Siliqua Fruit Extract Masking, Skin Conditioning

We don't have a description for Ceratonia Siliqua Fruit Extract.

Unknown Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Polymethylsilsesquioxane
Silicon Icon
SiliconSilicon Icon

Polymethylsilsesquioxane is a silicone used as a film forming agent.

Disliked Full details ->
Sodium Peg-7 Olive Oil Carboxylate Emulsifying
Oil Icon
OilOil Icon

Sodium Peg-7 Olive Oil Carboxylate is an oil.

Unknown Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Peg-7 Glyceryl Cocoate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-7 Glyceryl Cocoate is created from polyethylene glycol and fatty acids from coconut oil.

Very Disliked Full details ->
Acanthopanax Senticosus Root Extract Skin Conditioning, Soothing

We don't have a description for Acanthopanax Senticosus Root Extract.

Unknown Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Hydrolyzed Soy Protein Humectant, Skin Conditioning

This ingredient is a vegetable-derived protein made to mimic hydrolyzed collagen. It is created from soy, or glycine soja.

Disliked Full details ->
Cynara Scolymus Leaf Extract Skin Conditioning

We don't have a description for Cynara Scolymus Leaf Extract.

Polyquaternium-7

Polyquaternium-7 is a light to clear colored liquid. It is commonly found in haircare products for its film-forming and anti-static properties.

Unknown Full details ->
Hydrolyzed Yeast Protein Skin Conditioning

We don't have a description for Hydrolyzed Yeast Protein.

Unknown Full details ->
Palmitoyl Pentapeptide-4 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

You might know this ingredients as Matrixyl. It is a peptide.

Methylsilanol Tri-Peg-8 Glyceryl Cocoate Emulsifying, Skin Conditioning

We don't have a description for Methylsilanol Tri-Peg-8 Glyceryl Cocoate.

Unknown Full details ->
Methicone Emollient, Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Methicone is a type of silicone.

Unknown Full details ->
CI 77891 Cosmetic Colorant

Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.

Disliked Full details ->
CI 77492 Cosmetic Colorant

Ci 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.

Advanced Génifique Anti-Aging Face Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Hydroxyethylpiperazine Ethane Sulfonic Acid Buffering

We don't have a description for Hydroxyethylpiperazine Ethane Sulfonic Acid.

Ascorbyl Glucoside Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Sodium Benzoate Masking, Preservative
Preservative Icon
PreservativePreservative Icon

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Faex Extract Skin Conditioning

We don't have a description for Faex Extract.

Unknown Full details ->
Peg-20 Methyl Glucose Sesquistearate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-20 Methyl Glucose Sesquistearate isn't fungal acne safe.

Disliked Full details ->
Peg-60 Hydrogenated Castor Oil Emulsifying
Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.

Very Disliked Full details ->
Salicyloyl Phytosphingosine Skin Conditioning

We don't have a description for Salicyloyl Phytosphingosine.

Unknown Full details ->
Ammonium Polyacryloyldimethyl Taurate Emulsion Stabilising

Ammonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product.

Limonene Perfuming, Solvent
Fragrance Icon
FragranceFragrance Icon

Limonene is a fragrance that adds scent and taste to a formulation.

Very Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Octyldodecanol Emollient, Masking

Octyldodecanol is a fatty alcohol. It is primarily used to enhance the texture of products.

Disliked Full details ->
Citronellol Perfuming
Fragrance IconEU Allergen Icon
FragranceFragrance Icon EU AllergenEU Allergen Icon

Citronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".

Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting
Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Masking, Perfuming
Very Disliked

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

In the US, the alternative name for parfum is 'fragrance'.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

R.N.A. POWER Anti-Aging Essence Serum
11
5
17
11
liked
mixed
disliked
not rated
Advanced Génifique Anti-Aging Face Serum
9
1
12
2
liked
mixed
disliked
not rated

When to use

1 Routine
0% use in am
100% use in pm
100% use every day
188 Routines
45% use in am
55% use in pm
94% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Sk-II R.N.A. POWER Anti-Aging Essence Serum 44 ingredients

R.N.A. POWER Anti-Aging Essence Serum hasn't been rated yet.
Rate it now

Lancôme Advanced Génifique Anti-Aging Face Serum 24 ingredients

4.8 /5
from 5 ratings
mrsmatt12's avatar

mrsmatt12

12 months ago · Dry Skin
Review

I've been using this for years and consistently get compliments on my 58 yr old skin

deebeec's avatar

deebeec

10 months ago · Combination Skin
Review

It's just really good. Very expensive though.