Updated on December 28, 2023
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 16 ingredients in common
Cool Features
They both contain hyaluronic acid and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MediCube Age-R Glutathione Glow Serum 43 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
At a glance
Click on any of the items below to learn more
MediCube Age-R Glutathione Glow Serum 43 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
Notable Ingredients
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Benefits
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.
Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.
Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Aroma refers to an ingredient, or mixture of ingredients, that impart or mask a flavor.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.
Cyanocobalamin is the manufactured version of vitamin B12. Our bodies use B12 for cell production.
Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Soluble Collagen can help to reduce the effects of aging.
4 Benefits May cause irritation
Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
Sodium Stearoyl Glutamate is an emulsifier and helps condition the skin. It is amino acid-based.
Water, Glycerin, Peg-8, Niacinamide, Butylene Glycol, Methylpropanediol, 1,2-Hexanediol, Betaine, Glycereth-26, Bis-Peg-18 Methyl Ether Dimethyl Silane, Polyglyceryl-10 Laurate, Bifida Ferment Lysate, Methyl Gluceth-20, Panthenol, Squalane, Glucosylrutin, Hydrogenated Lecithin, Carbomer, Caprylic/Capric Triglyceride, Tromethamine, Xanthan Gum, Propanediol, Aroma, Ethylhexylglycerin, Glutathione, Adenosine, Ceramide NP, Sodium Phytate, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Dextrin, Theobroma Cacao Extract, Beta-Glucan, Cyanocobalamin, Sodium Hyaluronate Crosspolymer, Tocopherol, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Soluble Collagen, Hyaluronic Acid, Sodium Acetylated Hyaluronate, Sodium Stearoyl Glutamate
Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Not safe for Fungal Acne
Galactomyces Ferment Filtrate (GFF) is a yeast traditionally used to make the Japanese alcoholic beverage, sake.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Alteromonas Ferment Extract is derived from a bacteria from in deep sea water.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Polyglyceryl-3 Distearate isn't fungal acne safe.
Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.
Polyglyceryl-3 Methylglucose Distearate is created from the diester of stearic acid and the condensation product of methylglucose and Polyglycerin-3.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Bifida Ferment Lysate 42%, Galactomyces Ferment Filtrate 21%, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, Peg-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Ferment Extract, Silk Extract, Goat Milk Extract, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Ethylhexylglycerin, Caprylyl Glycol, Tropolone, Disodium EDTA
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.
Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.
Learn more about Bifida Ferment LysateMethyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
It is created by combining polyethylene glycol with glucose.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
This ingredient is also referred to as pro-vitamin B5 or dexpanthenol in dermatology.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
Learn more about PanthenolSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneCarbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.
Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about TromethamineXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateIngredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
MediCube Age-R Glutathione Glow Serum 43 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
Reviews
Here's what our community thinks
MediCube Age-R Glutathione Glow Serum 43 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
cgi
numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish...
numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish serum.
i've only been using this since march of last year and it has been a game-changer ever since. i feel a bit dramatic when i say this, but i genuinely have seen a big difference in my skin using this compared to any other serum i've ever used. it blended in with my routine sooo unbelievably well. i don't know what type of witchcraft or sorcery is in this, but this product is a blessing and it's money VERY well-spent. beautiful bottle, it's like glass or something. it's a bit expensive, but you get so much product that'll last you way longer than a year. like i've had this since MARCH, and i still have over half the bottle left even though i use 3 drops every single night religiously.
it's hydrating, makes my skin very smooth (as it should), and has gone above and beyond in improving my skin texture. it miraculously decreased so many of the little bumps i get. it also absorbs very well under my base, literally just cleared my skin and boosted the glass skin look. i love this serum please buy it.
anniec
I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it...
I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it didn't fix was the stubborn closed comedones on my jaw and chin which wont go away no matter what.
