Versus

Estée Lauder Perfectionist Pro Multi-Defense UV Fluid SPF 45 Versus ISDIN Fotoprotector Fusion Fluid SPF 50+

Sunscreen
Sunscreen
American Brand United States
Spanish Brand Spain

Updated on May 26, 2025

Overview

What they are

These products are both sunscreens. They have a total of 7 ingredients in common

Cool Features

They both contain exfoliants, hyaluronic acid, SPF, Vitamin C and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, oils, parabens or sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Perfectionist Pro Multi-Defense UV Fluid SPF 45

Titanium Dioxide 6.3%

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Zinc Oxide 4%

Cosmetic Colorant
1 / 0 Mineral UV Filter IconHelps fight Acne IconNon-Reef-Safe Icon

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Butyloctyl Salicylate

Skin Conditioning
Non-Reef-Safe Icon

C12-15 Alkyl Benzoate

Antimicrobial

Methyl Trimethicone

Skin Conditioning
Silicon Icon

Isononyl Isononanoate

Emollient

Diethylhexyl Succinate

Emollient
2 / 0

Neopentyl Glycol Diheptanoate

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dipentaerythrityl Tri-Polyhydroxystearate

Emollient
Not safe for Fungal Acne Icon

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Skin Conditioning
Silicon Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Trimethylsiloxysilicate

Emollient
Silicon Icon

Cetyl PEG/PPG-10/1 Dimethicone

Emulsifying
Silicon Icon

Hydroxyapatite

Abrasive
Exfoliant Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Hordeum Vulgare Extract

Emollient

Triticum Vulgare Germ Extract

Skin Conditioning

Thermus Thermophillus Ferment

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Tuna Extract

Skin Conditioning

Lilium Tigrinum Extract

Skin Conditioning

Algae Extract

Emollient
May worsen Oily Skin Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Anthemis Nobilis Flower Extract

Masking
Fragrance IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Ergothioneine

Antioxidant
Antioxidant IconHelps reduce irritation IconGood for Dark Spots Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dimethicone Silylate

Silicon Icon

Hydrolyzed Wheat Protein/Pvp Crosspolymer

Dimethicone Crosspolymer-3

Skin Conditioning
Silicon Icon

Glyceryl Behenate/Eicosadioate

Emollient
Not safe for Fungal Acne Icon

Stearalkonium Hectorite

Gel Forming

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Isostearic Acid

Cleansing
Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyhydroxystearic Acid

Emulsifying
Not safe for Fungal Acne Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Dipropylene Glycol

Humectant

Triethoxycaprylylsilane

Silicon Icon

Ethylbisiminomethylguaiacol Manganese Chloride

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps with Anti-Aging IconGood for Dark Spots Icon

Cyclodextrin

Absorbent

Dimethicone/PEG-10/15 Crosspolymer

Silicon Icon

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Propylene Carbonate

Solvent

BHT

Antioxidant
Antioxidant Icon

Phenoxyethanol

Preservative
Preservative Icon

CI 45410

Cosmetic Colorant
2 / 0

CI 42090

Cosmetic Colorant

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Abrasive, Absorbent

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Cosmetic Colorant, UV Absorber, UV Filter

Titanium dioxide is a mineral UV filter widely used in sunscreens and cosmetics.

It is one of only two UV filters officially classified as “mineral” by regulatory agencies, the other being zinc oxide.

Titanium dioxide provides broad-spectrum protection mostly in the UVB and UVAII range, with some protection in the UVAI range.

While its UVA protection isn’t as strong as zinc oxide’s, the difference is minor.

A common myth is that mineral UV filters reflect UV light. However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).

Thanks to its non-irritating nature, titanium dioxide is suitable for sensitive, acne-prone, or redness-prone skin. It is unlikely to cause "eye sting" like other sunscreen ingredients.

A major drawback of this ingredient is its white cast and thick texture. This is why mineral sunscreens often leave a white cast and are less cosmetically elegant than chemical/hybrid sunscreens.

To improve white cast and spreadability, micronized or nano-sized titanium dioxide is often used.

There are ongoing concerns surrounding nano-titanium oxide's impact on marine ecosystems.

There is no conclusive evidence that any form of titanium oxide (or any other sunscreen ingredients) will cause harm to marine ecosystems or coral reefs. The science is still developing but many consumers are keeping a close eye on this issue.

Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.

Nano mineral sunscreens once raised safety concerns about absorption into skin.

Extensive research has shown that they do not penetrate healthy or damaged skin; they remain safely on the surface and the top layer of dead skin (stratum corneum).

You'll likely find titanium dioxide bundled with alumina, silica, or dimethicone. These ingredients help make titanium dioxide highly photostable; this prevents it from interacting with other formula components under UV light.

Learn more about Titanium Dioxide
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

1 Routine
100% use in am
0% use in pm
100% use every day