Dr.Leo Multi Effect Isolation Cream Versus L.SANIC AC Clinic Mattifying Oil-Free Fluid SPF 15
Updated on April 02, 2025
Overview
What they are
These products are both fungal acne (malassezia) safe . They have a total of 17 ingredients in common
Cool Features
They both contain hyaluronic acid, niacinamide and SPF
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils or parabens
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr.Leo Multi Effect Isolation Cream 38 ingredients
L.SANIC AC Clinic Mattifying Oil-Free Fluid SPF 15 34 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Dr.Leo Multi Effect Isolation Cream 38 ingredients
L.SANIC AC Clinic Mattifying Oil-Free Fluid SPF 15 34 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Niacinamide
Smoothing
Sodium Hyaluronate
Humectant
Bifida Ferment Lysate
Skin Conditioning
Tremella Fuciformis Sporocarp Extract
Antioxidant
Abelmoschus Esculentus Fruit Extract
Skin ConditioningChamomilla Recutita Flower Extract
Masking
Glycyrrhiza Glabra Root Extract
Bleaching
Camellia Sinensis Leaf Extract
Antimicrobial
Cladosiphon Novae-Caledoniae Extract
HumectantPolygonum Cuspidatum Root Extract
Antioxidant
Centella Asiatica Extract
Cleansing
Sodium Acetylated Hyaluronate
Humectant
Rosmarinus Officinalis Leaf Extract
AntimicrobialScutellaria Baicalensis Root Extract
AstringentSodium Hyaluronate Crosspolymer
Humectant
Hydrolyzed Sodium Hyaluronate
Skin ConditioningCyclopentasiloxane
Emollient
Propylene Glycol
Humectant
Titanium Dioxide
Cosmetic Colorant
Cyclohexasiloxane
Emollient
Glycereth-26
HumectantPEG-10 Dimethicone
Skin Conditioning
PEG-10 Dimethicone/Vinyl Dimethicone Crosspolymer
StabilisingMagnesium Sulfate
Isononyl Isononanoate
Emollient1,2-Hexanediol
Skin ConditioningHydroxyacetophenone
Antioxidant
CI 77007
Cosmetic ColorantMagnesium Stearate
Cosmetic ColorantC12-15 Alkyl Benzoate
AntimicrobialPhenyl Trimethicone
Skin Conditioning
Butylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningCetyl PEG/PPG-10/1 Dimethicone
Emulsifying
Triethoxycaprylylsilane
Aroma
Water, Glycerin, Niacinamide, Sodium Hyaluronate, Bifida Ferment Lysate, Tremella Fuciformis Sporocarp Extract, Abelmoschus Esculentus Fruit Extract, Chamomilla Recutita Flower Extract, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Cladosiphon Novae-Caledoniae Extract, Polygonum Cuspidatum Root Extract, Centella Asiatica Extract, Sodium Acetylated Hyaluronate, Rosmarinus Officinalis Leaf Extract, Scutellaria Baicalensis Root Extract, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Cyclopentasiloxane, Propylene Glycol, Titanium Dioxide, Cyclohexasiloxane, Glycereth-26, PEG-10 Dimethicone, PEG-10 Dimethicone/Vinyl Dimethicone Crosspolymer, Magnesium Sulfate, Isononyl Isononanoate, 1,2-Hexanediol, Hydroxyacetophenone, CI 77007, Magnesium Stearate, C12-15 Alkyl Benzoate, Phenyl Trimethicone, Butylene Glycol, Pentylene Glycol, Cetyl PEG/PPG-10/1 Dimethicone, Triethoxycaprylylsilane, Aroma
Water
Skin ConditioningEthylhexyl Methoxycinnamate
UV Absorber
Ethylhexyl Salicylate
UV Absorber
Butylene Glycol
Humectant
Glycerin
Humectant
Niacinamide
Smoothing
Butyl Methoxydibenzoylmethane
UV Absorber
Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin Conditioning
Methylene Bis-Benzotriazolyl Tetramethylbutylphenol
UV Filter
Decyl Glucoside
CleansingPropylene Glycol
Humectant
Xanthan Gum
Emulsifying1,2-Hexanediol
Skin ConditioningSodium Hyaluronate
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Hydroxypropyltrimonium Hyaluronate
Pentylene Glycol
Skin ConditioningSodium Hyaluronate Crosspolymer
Humectant
Sodium Acetylated Hyaluronate
Humectant
Lavandula Angustifolia Flower Water
Skin ConditioningSalvia Sclarea Extract
AntiseborrhoeicHyacinthus Orientalis Extract
Skin ConditioningChamomilla Recutita Flower/Leaf Extract
AntimicrobialBorago Officinalis Extract
Emollient
Centaurea Cyanus Flower Extract
AstringentCentella Asiatica Extract
Cleansing
Polygonum Cuspidatum Root Extract
Antioxidant
Scutellaria Baicalensis Root Extract
AstringentCamellia Sinensis Leaf Extract
Antimicrobial
Glycyrrhiza Glabra Root Extract
Bleaching
Chamomilla Recutita Flower Extract
Masking
Rosmarinus Officinalis Leaf Extract
AntimicrobialEthylhexylglycerin
Skin ConditioningBis-Stearyl PEG/PPG-8/6 Smdi/PEG-400 Copolymer
Water, Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate, Butylene Glycol, Glycerin, Niacinamide, Butyl Methoxydibenzoylmethane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Decyl Glucoside, Propylene Glycol, Xanthan Gum, 1,2-Hexanediol, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Pentylene Glycol, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Lavandula Angustifolia Flower Water, Salvia Sclarea Extract, Hyacinthus Orientalis Extract, Chamomilla Recutita Flower/Leaf Extract, Borago Officinalis Extract, Centaurea Cyanus Flower Extract, Centella Asiatica Extract, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Ethylhexylglycerin, Bis-Stearyl PEG/PPG-8/6 Smdi/PEG-400 Copolymer
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateChamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractGlycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Learn more about Glycyrrhiza Glabra Root ExtractCamellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
This ingredient has many skin benefits:
This ingredient contains polyphenols, a strong antioxidant. Antioxidants help fight off molecules that damage skin cells.
On top of that, the antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.
Many components of tea have anti-inflammatory properties.
Polyphenols and L-theanine help soothe the skin and reduce irritation. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.
Other compounds found in tea include: Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.
Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.
Learn more about Camellia Sinensis Leaf ExtractPolygonum Cuspidatum Root Extract comes from the Japanese Knotweed plant native to Japan, Korea, and China.
This plant contains anti-inflammatory and antioxidant properties. It contains high amounts of resveratrol, a potent antioxidant.
The root of the plant has been used in traditional folk medicine throughout Asia.
Learn more about Polygonum Cuspidatum Root ExtractCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractSodium Acetylated Hyaluronate is a type of Hyaluronic Acid.
Hyaluronic Acids help moisturize, soothe, and protect the skin.
Read about common types of Hyaluronic Acid here: Sodium Hyaluronate Hydrolyzed Hyaluronic Acid Hyaluronic Acid
Learn more about Sodium Acetylated HyaluronateRosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.
Rosemary Leaf Extract can help protect your skin against damage from free-radical molecules. It contains many antioxidants such as rosmarinic acid and caffeic acid.
Rosemarinic acid has been found to help soothe skin conditions such as eczema and acne.
Learn more about Rosmarinus Officinalis Leaf ExtractScutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.
In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.
Learn more about Scutellaria Baicalensis Root ExtractSodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate CrosspolymerPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene Glycol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolIngredient Ratings
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